Gonadotropins: From Bench Side to Bedside

Gonadotropins: From Bench Side to Bedside

1st Edition - July 1, 2016

Write a review

  • Author: Rajendra Kumar
  • eBook ISBN: 9780128012666
  • Hardcover ISBN: 9780128010587

Purchase options

Purchase options
DRM-free (Mobi, EPub, PDF)
Available
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, from research to treatment.

Key Features

  • Contains contributions from leading authorities on the topic
  • Publishes cutting-edge reviews in molecular biology
  • Informs and updates on all the latest developments available regarding the research of gonadotropins

Readership

Students, researchers, microbiologists, molecular biologists

Table of Contents

  • Chapter One: Mouse Models of Gonadotrope Development

    • Abstract
    • 1. Introduction
    • 2. Signaling Pathways
    • 3. Transcription Factors
    • 4. CRE Mice for Targeting Gonadotropes
    • 5. Concluding Remarks

    Chapter Two: Mouse Models for the Study of Synthesis, Secretion, and Action of Pituitary Gonadotropins

    • Abstract
    • 1. Introduction
    • 2. α-Glycoprotein Hormone Subunit
    • 3. LHβ Subunit
    • 4. FSHβ Subunit
    • 5. Transforming Growth Factor-β Superfamily Members and Gonadotropins
    • 6. Other Mouse Models
    • 7. Conclusions and Future Directions
    • Acknowledgments

    Chapter Three: Clinical Applications of Gonadotropins in the Female: Assisted Reproduction and Beyond

    • Abstract
    • 1. Introduction
    • 2. Molecular Biology of the Ovarian Response
    • 3. Gonadotropins in Assisted Reproduction
    • 4. Ovarian Stimulation Protocols in ART
    • 5. Adverse Events in Ovarian Stimulation
    • 6. Gonadotropins Beyond ART
    • 7. Conclusions
    • Acknowledgments

    Chapter Four: Clinical Applications of Gonadotropins in the Male

    • Abstract
    • 1. Introduction
    • 2. Structural Features of the Gonadotropins
    • 3. Regulation of the Synthesis and Secretion of the Pituitary Gonadotropins
    • 4. Gonadotropin Secretion
    • 5. Pharmacokinetics of Gonadotropins
    • 6. Gonadotropin Formulations Available for Treating Hypogonadotropic Hypogonadism and Infertility in Men
    • 7. Treatment with Gonadotropins in the Male
    • 8. Concluding Remarks
    • Acknowledgments

    Chapter Five: Beyond Reproduction: Pituitary Hormone Actions on Bone

    • Abstract
    • 1. Evolutionary Considerations
    • 2. Epidemiology Suggests an FSH–Bone Connection
    • 3. FSH Directly Affects the Skeleton
    • 4. FSH Signals Through FSHRs on Bone Cells
    • 5. FSH Antibody Rescues Hypogonadal Bone Loss
    • 6. Oxytocin is Anabolic to Bone
    • 7. Oxytocin and Skeletal Regulation During Reproduction
    • 8. Prolactin and Bone

    Chapter Six: Gonadotrope Tumors

    • Abstract
    • 1. Introduction
    • 2. Gonadotropes in the Normal Pituitary
    • 3. Gonadotrope Hyperplasia
    • 4. Gonadotrope Tumors
    • 5. Conclusions

Product details

  • No. of pages: 230
  • Language: English
  • Copyright: © Academic Press 2016
  • Published: July 1, 2016
  • Imprint: Academic Press
  • eBook ISBN: 9780128012666
  • Hardcover ISBN: 9780128010587

About the Author

Rajendra Kumar

Professor T. Rajendra Kumar works at the Department of Obstetrics & Gynecology, University of Colorado Denver.

Affiliations and Expertise

Department of Obstetrics & Gynecology, University of Colorado Denver, Aurora, CO, USA

Ratings and Reviews

Write a review

There are currently no reviews for "Gonadotropins: From Bench Side to Bedside"