Gonadotropins: From Bench Side to Bedside - 1st Edition - ISBN: 9780128010587, 9780128012666

Gonadotropins: From Bench Side to Bedside, Volume 143

1st Edition

Authors: Rajendra Kumar
eBook ISBN: 9780128012666
Hardcover ISBN: 9780128010587
Imprint: Academic Press
Published Date: 1st July 2016
Page Count: 230
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Table of Contents

  • Contributors
    • Preface
      • Chapter One: Mouse Models of Gonadotrope Development
        • Abstract
        • 1. Introduction
        • 2. Signaling Pathways
        • 3. Transcription Factors
        • 4. CRE Mice for Targeting Gonadotropes
        • 5. Concluding Remarks
      • Chapter Two: Mouse Models for the Study of Synthesis, Secretion, and Action of Pituitary Gonadotropins
        • Abstract
        • 1. Introduction
        • 2. α-Glycoprotein Hormone Subunit
        • 3. LHβ Subunit
        • 4. FSHβ Subunit
        • 5. Transforming Growth Factor-β Superfamily Members and Gonadotropins
        • 6. Other Mouse Models
        • 7. Conclusions and Future Directions
        • Acknowledgments
      • Chapter Three: Clinical Applications of Gonadotropins in the Female: Assisted Reproduction and Beyond
        • Abstract
        • 1. Introduction
        • 2. Molecular Biology of the Ovarian Response
        • 3. Gonadotropins in Assisted Reproduction
        • 4. Ovarian Stimulation Protocols in ART
        • 5. Adverse Events in Ovarian Stimulation
        • 6. Gonadotropins Beyond ART
        • 7. Conclusions
        • Acknowledgments
      • Chapter Four: Clinical Applications of Gonadotropins in the Male
        • Abstract
        • 1. Introduction
        • 2. Structural Features of the Gonadotropins
        • 3. Regulation of the Synthesis and Secretion of the Pituitary Gonadotropins
        • 4. Gonadotropin Secretion
        • 5. Pharmacokinetics of Gonadotropins
        • 6. Gonadotropin Formulations Available for Treating Hypogonadotropic Hypogonadism and Infertility in Men
        • 7. Treatment with Gonadotropins in the Male
        • 8. Concluding Remarks
        • Acknowledgments
      • Chapter Five: Beyond Reproduction: Pituitary Hormone Actions on Bone
        • Abstract
        • 1. Evolutionary Considerations
        • 2. Epidemiology Suggests an FSH–Bone Connection
        • 3. FSH Directly Affects the Skeleton
        • 4. FSH Signals Through FSHRs on Bone Cells
        • 5. FSH Antibody Rescues Hypogonadal Bone Loss
        • 6. Oxytocin is Anabolic to Bone
        • 7. Oxytocin and Skeletal Regulation During Reproduction
        • 8. Prolactin and Bone
      • Chapter Six: Gonadotrope Tumors
        • Abstract
        • 1. Introduction
        • 2. Gonadotropes in the Normal Pituitary
        • 3. Gonadotrope Hyperplasia
        • 4. Gonadotrope Tumors
        • 5. Conclusions
      • Index

        Description

        Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, from research to treatment.

        Key Features

        • Contains contributions from leading authorities on the topic
        • Publishes cutting-edge reviews in molecular biology
        • Informs and updates on all the latest developments available regarding the research of gonadotropins

        Readership

        Students, researchers, microbiologists, molecular biologists


        Details

        No. of pages:
        230
        Copyright:
        © Academic Press 2016
        Published:
        Imprint:
        Academic Press
        eBook ISBN:
        9780128012666
        Hardcover ISBN:
        9780128010587

        Reviews

        Praise for the Series:
        "Maintains the tradition and set-up of the previous volumes and certainly provides up-to-date data on varied aspects of cytology... a valuable acquisition to any library." --The Nucleus


        About the Authors

        Rajendra Kumar Author

        Professor T. Rajendra Kumar works at the Department of Obstetrics & Gynecology, University of Colorado Denver.

        Affiliations and Expertise

        Department of Obstetrics & Gynecology, University of Colorado Denver, Aurora, CO, USA