Glycoconjugate Research

Glycoconjugate Research

Proceedings of the Interior Symposium on Glycoconjugates

1st Edition - January 1, 1979

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  • Editor: John Gregory
  • eBook ISBN: 9780323145329

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Description

Glycoconjugate Research, Volume II contains the proceedings of the Fourth International Symposium on Glycoconjugates held in Woods Hole, Massachusetts in 1977. The papers explore the biosynthesis and regulation of glycoconjugates, particularly those of cell membranes, and glycolipid storage diseases. This volume is comprised of 95 chapters divided into three sections. After reviewing the regulatory mechanisms underlying glycoprotein synthesis, it turns to enzymic modifications of sialic acids in the course of glycoconjugate biosynthesis. The following chapters focus on the biosynthesis and characterization of lipid-linked sugars in the outer membrane of liver mitochondria; effect of bacitracin on the biosynthesis of dolichol derivatives in calf pancreas microsomes; secretion of proteoglycans by chondrocytes; and heterogeneity of arterial proteoglycans. The biosynthesis of elastin by chondroblasts in monolayer cultures is also considered, along with the phosphorylation of proteoglycans in human articular cartilage. The final chapter describes a double-antibody radioimmunoassay for soluble and cell-surface blood group Ii antigens. This book will be a useful resource for biochemists.

Table of Contents


  • Contents of Volume

    Biosynthesis and Regulation

    The Control of Glycoprotein Synthesis

    Enzymic Modifications of Sialic Acids in the Course of Glycoconjugate Biosynthesis

    Role of Lipid-Saccharide Intermediates in Glycoprotein Biosynthesis

    Distinction and Partial Characterization of Two Galactosyltransferase Activities in Normal Human Serum

    Characterization of Two Highly Purified Fucosyltransferases

    Purification by Affinity Chromatography and Properties of Microsomal Galactosyltransferase from Pig Thyroid

    Sheep Brain Glycoprotein Fucosyltransferase

    The Incorporation of [14C]Glucosamine into Glycosaminoglycans and the Influence of Corneal Epithelium onThis Process

    Biosynthesis of Blood Group N- and M-Specific Haptenic Structures by Human Serum Glycosyltransferases

    Biosynthesis and Characterization of Lipid-Linked Sugars in Outer Membrane of Liver Mitochondria

    Incorporation of N-Acetylglucosamine and Mannose in Rat Liver Rough Microsomes: Stimulation by GTP after Treatment with Pyrophosphate

    Release of Complex Carbohydrates into Culture Medium by Cultured Hamster Cells

    On the Biosynthesis of Carboxypeptidase Y(CY)

    Metabolism of Free Sialic Acid, CMP-Sialic Acid, and Bound Sialic Acid in Rat Brain

    Effect of Bacitracin on the Biosynthesis of Dolichol Derivatives in Calf Pancreas Microsomes

    Biosynthesis of Dolichol Derivatives Containing D-Galactose in Calf Pancreas Microsomes

    Sulfogalactosyl Glycerides (SGG) from Rat Brain Myelin

    Complex Formation by Sequential Glycosyltransferases

    Biosynthesis of Heparin: Tritium Incorporation into Chemically Modified Heparin Catalyzed by C-5-Uronosylepimerase

    Serum Glycosyltransferase Enzymes in Normal and Leukemic Subjects: Experiences with Low-Molecular-Weight Acceptors

    Transfer of Glucose to Phenolic Steroids and Possible Physiological Role of the Glucosides

    Secretion of Proteoglycans by Chondrocytes. Influence of Colchicine, Cytochalasin B, and β-D-Xyloside

    Glycosyl Transfer to Bovine Rhodopsin

    Changes in Glycoproteins and Glycolipids of the Ghosh-Lai Rat Stomach following Perfusions with Ethanol

    Heterogeneity of Arterial Proteoglycans

    Structural Changes of Sulfated Proteoglycans of the Growth Cartilage of Rats during Endochondral Calcification

    Composition and Biosynthesis of Rat Glomerular Basement Membrane in Sucrose-Fed Rats

    Biosynthesis of Elastin by Chondroblasts in Monolayer Cultures

    N-Glycosylation of Asparagine Residues in Subtilisin, Lysozyme, and Synthetic Peptides by Microsomal Transferases

    Glycolipid Intermediates Involved in the Transfer of N-Acetylglucosamine to Endogenous Proteins in Yeast

    Purification and Characterization of Two Sialyltransferase Activities from Porcine Submaxillary Glands

    Mannosyl Retinyl Phosphate: Its Role as a Donor of Mannose to Glycoconjugates in Rat Liver Membranes

    Isolation and Properties of Acylneuraminate Cytidylyltransferase from Frog Liver

    Sugar-Modified Lysozyme as N-Acetylneuraminic Acid Acceptor

    2-Deoxy-D-glucose, 2-Deoxy-2-fluoro-oglucose, and 2-Deoxy-2-fluoro-D-mannose as Inhibitors of Glycosylation

    Phosphorylation of Proteoglycans in Human Articular Cartilage

    Composition of the Chondroitin Sulfate Proteoglycan Produced by β-D-Xyloside-Treated Chondrocytes

    Properties of a Mannosyltransferase from Rabbit Liver

    A Structural Glycoprotein of Elastic Tissue: Its Synthesis by Cultured Fibroblasts

    Isolation and Characterization of Rat Stomach Glycoprotein

    Intracellular Site of Glycosyl- and Sulfate-Transferases in the Surface Mucous-Cells of the Rat Stomach

    Synthesis and Metabolic Effects of Halogenated L-Fucose and D-Galactose Analogs

    Studies on Immature Articular Cartilage

    Effects of Tunicamycin on Procollagen Synthesis and Secretion

    Biochemical Studies of the Matrix of Cranio-Vertebral Chordoma and a Metastasis

    Cell-Free Synthesis of Cartilage Specific Proteins

    Sialylation of Desialylated Ovine Submaxillary Mucin by Porcine Liver Sialyltransferase In Vitro

    Chemical Synthesis of α-N-Acetylhyalobiuronic Acid Phosphate Derivatives

    Role of Synthetic Phosphate Diesters in Study of Bacterial Cell Wall

    Incorporation of N-Acetylglucosamine and Mannose in Rat Liver Microsomes: Submicrosomal Localization and Effect of the Removal of Bound Ribosomes

    Alterations in Heparan Sulfate after SV40 Transformation

    The Effect of Hyaluronic Acid on the Synthesis of Proteoglycans by Chondrocytes

    Metabolic Disorders and Degradation

    Present Status of Research in the Glycolipid Storage Diseases

    Comparative Study of α-L-Fucosidases from Three Species of Marine Molluscs: Purification and Properties

    Purification and Properties of α-L-Fucosidase from Venus mercenaria

    Regulation of Glycosphingolipid Synthesis in Cloned-Cell Strains of Nervous System Origin

    Preparation and Properties of an endo-β-Ν-Acetylglucosaminidase from Rabbit Serum

    Progress Report on the Treatment of Hurler's Disease by Enzyme Replacement Therapy

    N-Acetylglucosamine 6-Sulfate Sulfatase Deficiency: A New Mucopolysaccharidosis

    On the Mode of Participation of Hyaluronidase and Exoglycosidases in the Degradation of Hyaluronic Acid and Chondroitin 4-Sulfate with Canine Liver Lysosomes

    Levels of Two Plasma Fucosyltransferases as an Index of Disease Status in Patients with Acute Myelogenous Leukemia

    Characterization of Urinary Glycoconjugates in Mucolipidoses I-IV

    Hydrolysis of Tay-Sachs Ganglioside by ß-N-AcetylhexosaminidaseA Isolated from Human Liver

    Heterogeneity of Rat Rib Chondroitin Sulfate and Susceptibility to Rat Gastric Chondrosulfohydrolase

    Chemical and Cytochemical Studies of Heparan Sulfates from AH-130 Ascites Hepatoma

    Altered Kinetic Behavior of Immobilized Glycosidases

    Comparison of Particulate Neuraminidases from Human Heart and Brain

    Isolation and Characterization of Glycosaminoglycans from Pulmonary Secretions of Patients with Alveolar Proteinosis

    Demonstration of Glycoprotein- and Glycolipid-Specific Neuraminidases in Horse Liver

    Degradation of Nucleoside Diphosphate Sugars by Human and Rat Serum. Properties of the Serum Nucleotide Pyrophosphatases

    Hydrolysis of Various Oligosaccharides and a Glycopeptide Core Derived from Glycoproteins by N-Acetyl-ß-D-hexosaminidases A and Β Isolated from Human Liver

    Precursors of the Blood Group NM Antigens Are Human Carcinoma-Associated

    Structure of Oligosaccharides and Glycopeptides Excreted in Urine of Patients with Catabolism Defect of Glycoproteins (Sialidosis, Fucosidosis, Mannosidosis, and Sandhoff s Disease)

    Determination by High-Performance Liquid Chromatography of the Decrease of Seminolipid Content in Rats with Vitamin A Deficiency

    Inhibition of Lysosomal Enzyme Endocytosis by Carbohydrate and Lectins

    Properties of Arthrobacter sialophilus Neuraminidase

    Characterization of Reference Disaccharides from Nitrous Acid Deamination of Beef Lung Heparin

    Glycoconjugates of Cell Membranes

    Cell Growth Control and Antigenic Expression through Membrane Glycosphingolipids

    Cell Surface Carbohydrates in Relation to Receptor Activity

    Subcellular Distribution of Glycoprotein-Bound Sialic Acid in Rat Liver

    Viability of Erythrocytes in Circulation and Its Dependence on Cell Surface Glycoconjugates

    Translocation of Enzymic Glycoproteins within Yeast Cell Envelopes

    Purification of Human Blood Group B Gene-Associated 3-α-D-Galactosyltransferase by Biospecific Adsorption onto Group O Erythrocyte Membranes

    Isolation and Partial Characterization of "Galactoprotein a" (LETS) and "Galactoprotein b" from Hamster Embryo Fibroblasts

    Isolation and Characterization of Surface Glycopeptides from Adult Rat Hepatocytes in an Established Line

    A Facile Preparation of High-Molecular-Weight, Water-Soluble, A,B,H(O)-Active Glycolipids from Human Erythrocyte Membranes

    Partial Characterization of Lectin-Binding Glycoproteins Released from Ascites Hepatoma Cell-Surface

    An α-D-Galactopyranosyl-Containing Glycoprotein from Ehrlich Ascites Tumor Cell Plasma Membranes

    Glycoproteins from the Bovine Erythrocyte Membrane

    Stepwise-Crosslinking Reagents for Photocoupling of Enzymes and Lectins to Mammalian Cells

    The Use of Dansylhydrazine as a Fluorescent Label Specific for Cell Surface Sialic Acid

    Membrane and Soluble Glycosyltransferases in Colchicine-Treated Rats. Marked Increase of Sialyltransferase in Serum

    Isolation and Partial Structure of an Oligosaccharide of Band-3 Glycoproteins of Human Erythrocyte Membranes

    Intestinal Glycoprotein Synthesis and the Redistribution of Glycoproteins into Different Parts of the Surface Membrane

    Fucose-Containing Glycoproteins from Cell Surface Membrane of Hamster Cells Transformed by Herpes simplex Virus (Type I): Isolation and Some Molecular Properties of a Membrane Glycoprotein with Alkaline Pyrophosphatase Activity

    A Study of Glycosphingolipids in Cultured Cell Lines from Human Colonic Tumors and Fetal Intestines

    Structural Differentiation between the Moloney Leukemia Virus-Determined Cell Membrane Antigen and Virion Structural Proteins

    Comparative Study of Ectogalactosyl- and Ectosialyltransferases of Lymphocytes

    A Double-Antibody Radioimmunoassay for Soluble and Cell-Surface Blood Group li Antigens

    Index for Volumes I and II




Product details

  • No. of pages: 581
  • Language: English
  • Copyright: © Academic Press 1979
  • Published: January 1, 1979
  • Imprint: Academic Press
  • eBook ISBN: 9780323145329

About the Editor

John Gregory

Affiliations and Expertise

University College, London

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