Glutamine: Metabolism, Enzymology, and Regulation

Glutamine: Metabolism, Enzymology, and Regulation

1st Edition - January 1, 1980

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  • Editor: Jaime Mora
  • eBook ISBN: 9780323154543

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Description

Glutamine: Metabolism, Enzymology, and Regulation presents significant contributions on the metabolism, enzymology, and regulation of glutamine of microorganisms to higher animals. The book is a collection of papers presented during the scientific symposium of the fiftieth anniversary of the granting of the autonomy of the University of Mexico, held in Hacienda Galindo, Queretaro, Mexico in November 1979. The monograph covers glutamine metabolism centered mainly in enzymatic studies on glutamine synthetase and the enzymes that utilize glutamine; the model of cascade control of glutamine synthetase in Escherichia coli; the mechanisms that control gene expression of glutamine synthetase and its relation to nitrogen metabolism in prokaryotes; the relationship between the structure and function of glutamine synthetase in eukaryotic microorganisms; nitrogen and glutamine metabolism in plants; the role of glutamine in the animal body; and the synthesis of glutamine in animal tissues. Biologists, botanists, and zoologists will find the compendium very insightful.

Table of Contents


  • Contributors

    Preface

    Introductory Remarks

    1. Catalytic Mechanisms of Glutamine Synthetase; Overview of Glutamine Metabolism

    2. The Interconvertible Enzyme Cascade That Regulates Glutamine Synthetase Activity

    3. The Role of Glutamine Synthetase in the Regulation of Bacterial Nitrogen Metabolism

    4. Regulation of Nitrogen Metabolism in Escherichia coli

    5. Analysis of Mutations Affecting the Regulation of Nitrogen Utilization in Salmonella Typhimurium

    6. Nitrogen Regulation in Salmonella Typhimurium

    7. Genetic Characterization of Mutations Affecting Glutamine Biosynthesis and Its Regulation in Escherichia coli K12

    8. Isolation of E. coli Chromosomal DNA Regions Carrying glnA, gdh, and gltB Structural Genes

    9. Role of Glutamine Synthetase in Nitrogen Fixation

    10. Neurospora Crassa Glutamine Synthetase: A Model to Study Gene Expression in Eukaryotes

    11. Glutamine Metabolism in Neurospora Crassa

    12. The Role of Glutamine in Ammonia Assimilation and Reassimilation in Plants

    13. Enterohepatic Aspects of Glutamine Metabolism

    14. Glutamine Metabolism in Skeletal Muscle

    15. Glutamine Metabolism in Brain

    16. Regulatory Aspects of the Induction of Glutamine Synthetase in Embryonic Neural Retina

    17. Enhancement of Glutamine Excretion as Phenylacetyl-Glutamine in the Treatment of Cases with Congenital Defects of Enzymes Involved in Urea Biosynthesis

    18. Special Lecture: Glutamine Metabolism in the Animal Body

    Index

Product details

  • No. of pages: 354
  • Language: English
  • Copyright: © Academic Press 1980
  • Published: January 1, 1980
  • Imprint: Academic Press
  • eBook ISBN: 9780323154543

About the Editor

Jaime Mora

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