Chapter One. General Introduction to Glucosinolates
- 1. Introduction
- 2. Biosynthesis
- 3. Localization of the Biosynthesis
- 4. Storage
- 5. Pathway Engineering
- 6. Transport Processes
- 7. Conclusions
Chapter Two. Complex Environments Interact With Plant Development to Shape Glucosinolate Profiles
- 1. Introduction
- 2. All Classes of Glucosinolates Can Change in Response to Pathogens and Herbivores
- 3. Changes in Abiotic Environmental Factors Modulate Glucosinolate Responses
- 4. Plants Integrate External and Internal Signals to Optimize Their Metabolism
- 5. Concluding Remarks
Chapter Three. Nonlinear Selection and a Blend of Convergent, Divergent and Parallel Evolution Shapes Natural Variation in Glucosinolates
- 1. Introduction
- 2. Loci
- 3. Evolutionary Implications
- 4. Future Perspectives for Understanding Glucosinolate Variation
Chapter Four. Glucosinolate Regulation in a Complex Relationship – MYC and MYB – No One Can Act Without Each Other
- 1. Introduction
- 2. Subgroup 12 R2R3-MYB Transcription Factors in Glucosinolate Regulation
- 3. Subgroup IIIe bHLH Transcription Factors in Glucosinolate Regulation
- 4. The MYC-bHLH Interact With the GSL-MYBs and Are Thereby Crucial Regulators of IG and AG
- 5. HIG-MYB-Dependent Effects on IG-Related Indolic Compounds
- 6. Glucosinolate-Feedback Mechanism
- 7. HIG-HAG Crosstalk – Possible Reasons for the Reciprocal Regulation of Aliphatic and Indolic Glucosinolates
- 8. Further Regulatory Proteins in Glucosinolate Regulation
- 9. Summary and Future Perspectives
Chapter Five. Glucosinolate Synthesis in the Context of Plant Metabolism
- 1. Introduction
- 2. Connection of Glucosinolates With Sulphur Metabolism
- 3. Redox Regulation
- 4. Transporters in Glucosinolate Synthesis
- 5. Conclusions
Chapter Six. Glucosinolate Breakdown
- 1. Introduction
- 2. Myrosinases
- 3. Specifier Proteins
- 4. Compartmentation
- 5. Structural Diversity of Breakdown Products Formed Upon Tissue Disruption and Their Impact on Plant Defence
- 6. Breakdown Inside Herbivores
- 7. Breakdown in Nondisrupted Tissue
- 8. Conclusions and Perspectives
Chapter Seven. The Function of Glucosinolates and Related Metabolites in Plant Innate Immunity
- 1. Introduction
- 2. Aliphatic Glucosinolates in Plant Immunity
- 3. Pathogen-Triggered Indole Glucosinolate Metabolism
- 4. Functional and Biosynthetic Relationships Between Indole Glucosinolates and Brassicaceae Phytoalexins
- 5. Mode of Action of Glucosinolate-Derived Products
- 6. Concluding Remarks
Chapter Eight. Insect Detoxification of Glucosinolates and Their Hydrolysis Products
- 1. Introduction: Glucosinolate Hydrolysis and Its Effects on Insect Herbivores
- 2. General Detoxification Strategies
- 3. Specialized Detoxification Strategies
- 4. Conclusion
Chapter Nine. Health Benefits of Glucosinolates
- 1. Glucosinolate Structure and Metabolism
- 2. Metabolic Fate in Humans
- 3. Evidence for Health Benefits From Epidemiology
- 4. Diet–Gene Interactions and the Role of Glutathione-S-Transferase Genotypes
- 5. Evidence for Health Benefits From Human Interventional Studies
- 6. Mechanisms of Bioactivity From Animal and Cell Models
- 7. Conclusion
Chapter Ten. Glucosinolates – The Agricultural Story
- 1. Introduction
- 2. Oilseed Rape – From Industrial to Food Plant
- 3. Consequences of an Abrupt Switch of Oilseed Rape Varieties in Agricultural Production
- 4. Knockout of Double Low Oilseed Rape Varieties by Severe Sulphur Deficiency
- 5. Genetic Changes in Glucosinolate Metabolism Modify Sulphur Utilisation, Natural Plant Health and Wildlife Interactions
- 6. Epilogue
- Supplementary Data