Glucose-6-Phosphate Dehydrogenase covers the proceedings of an international symposium on G6PD, held in November 1985 under the auspices of the National Institutes of Health and the City of Hope National Medical Center. The said conference is a response to the need for a comprehensive conference on the diverse subjects related to the enzyme G6PD. The book is divided into four parts. Part I includes topics related to G6PD deficiency and hemolytic anemia such as drug-induced and non-spherocytic hemolytic anemia; favism; and G6PD-related neonatal jaundice. Part II discusses G6PD variations; the origin of G6PD polymorphis; and the evolutionary aspect of G6PD and hexose-6-phosphate dehydrogenase. Part III covers the expression of the GD locus; insights into G6PD regulation; and G6PD as markers for tumor. Part IV tackles topics such as the molecular biology of G6PD; the analysis of the primary structure of human G6PD; and the molecular cloning of cDNA for G6PD. The text is recommended for biologists, biochemists, medical technologists, and doctors who would like to know more about G6PD and its importance.
Contents Preface Q6PD Deficiency and Hemolytic Anemia Drug-Induced Hemolytic Anemia and Non-Spherocytic Hemolytic Anemia Pharmacogenetic Interaction of Glucose-6-Phosphate Dehydrogenase Deficiency with Acetylation and Hydroxylation Favism: Epidemiological and Clinical Aspects Etiological Aspects of Favism Divicine and G6PD-Deficient Erythrocytes: An Integrated Model of Cytotoxicity in Favism G6PD-Related Neonatal Jaundice Regulation of Glucose-6-Phosphate Dehydrogenase in Normal and Variant Red Blood Cells Intraerythrocytic Stability of Normal and Mutant G6PD Oxidant-Induced Membrane Damage in G-6-PD Deficient Red Blood Cells G6PD Variation Origin of G6PD Polymorphism: Malaria and G6PD Deficiency G6PD Variants in Southern Asian Populations Glucose-6-Phosphate Dehydrogenase Deficiency and Malaria in Central Thailand G6PD Variation in India Glucose-6-Phosphate Dehydrogenase Variants in Japan Discussion Glucose-6-Phosphate Dehydrogenase from Leuconostoc Mesenteroides G6PD of Drosophilia melanogaster Glucose-6-Phosphate Dehydrogenase and Hexose-6-Phosphate Dehydrogenase : An Evolutionary Aspect Signals Regulating Glucose-6-P Dehydrogenase Levels in Rat Liver Hepatic Glucose-6-Phosphate Dehydrogenase : Nutritional and Hormonal Regulation of mRNA Levels Transcriptional and Post-Transcriptional Regulation of Uterine Glucose-6-Phosphate Dehydrogenase by Estradiol Expression of GD Locus G6PD as a Tool and a Target for Studies on X-Chromosome Linkage X-Inactivation in Females Heterozygous for G-6-PD Variants Mechanism of Mammalian X-Chromosome Inactivation Insights into G6PD Regulation from Studies of X Dosage Compensation Polyclonal Tumors G-6-PD as a Marker for Tumors Glucose-6-Phosphate Dehydrogenase and Mosaic Analysis of Human Atherosclerotic Lesions Molecular Biology
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- © Academic Press 1986
- 28th January 1986
- Academic Press
- eBook ISBN:
Chairman, Department of Basic & Clinical Research; Head, Division of Hematology/Oncology, Scripps Clinic & Research Foundation, La Jolla, CA; Clinical Professor of Medicine, University of California, San Diego, CA