Glucose-6-Phosphate Dehydrogenase

Glucose-6-Phosphate Dehydrogenase

1st Edition - January 28, 1986

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  • Editors: Akira Yoshida, Ernest Beutler
  • eBook ISBN: 9780323146296

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Description

Glucose-6-Phosphate Dehydrogenase covers the proceedings of an international symposium on G6PD, held in November 1985 under the auspices of the National Institutes of Health and the City of Hope National Medical Center. The said conference is a response to the need for a comprehensive conference on the diverse subjects related to the enzyme G6PD. The book is divided into four parts. Part I includes topics related to G6PD deficiency and hemolytic anemia such as drug-induced and non-spherocytic hemolytic anemia; favism; and G6PD-related neonatal jaundice. Part II discusses G6PD variations; the origin of G6PD polymorphis; and the evolutionary aspect of G6PD and hexose-6-phosphate dehydrogenase. Part III covers the expression of the GD locus; insights into G6PD regulation; and G6PD as markers for tumor. Part IV tackles topics such as the molecular biology of G6PD; the analysis of the primary structure of human G6PD; and the molecular cloning of cDNA for G6PD. The text is recommended for biologists, biochemists, medical technologists, and doctors who would like to know more about G6PD and its importance.

Table of Contents


  • Contents

    Preface

    Q6PD Deficiency and Hemolytic Anemia

    Drug-Induced Hemolytic Anemia and Non-Spherocytic

    Hemolytic Anemia

    Pharmacogenetic Interaction of Glucose-6-Phosphate Dehydrogenase Deficiency with Acetylation and Hydroxylation

    Favism: Epidemiological and Clinical Aspects

    Etiological Aspects of Favism

    Divicine and G6PD-Deficient Erythrocytes: An Integrated Model of Cytotoxicity in Favism

    G6PD-Related Neonatal Jaundice

    Regulation of Glucose-6-Phosphate Dehydrogenase in Normal and Variant Red Blood Cells

    Intraerythrocytic Stability of Normal and Mutant G6PD

    Oxidant-Induced Membrane Damage in G-6-PD Deficient Red Blood Cells

    G6PD Variation

    Origin of G6PD Polymorphism: Malaria and G6PD Deficiency

    G6PD Variants in Southern Asian Populations

    Glucose-6-Phosphate Dehydrogenase Deficiency and Malaria in Central Thailand

    G6PD Variation in India

    Glucose-6-Phosphate Dehydrogenase Variants in Japan

    Discussion

    Glucose-6-Phosphate Dehydrogenase from Leuconostoc Mesenteroides

    G6PD of Drosophilia melanogaster

    Glucose-6-Phosphate Dehydrogenase and Hexose-6-Phosphate Dehydrogenase : An Evolutionary Aspect

    Signals Regulating Glucose-6-P Dehydrogenase Levels in Rat Liver

    Hepatic Glucose-6-Phosphate Dehydrogenase : Nutritional and Hormonal Regulation of mRNA Levels

    Transcriptional and Post-Transcriptional Regulation of Uterine Glucose-6-Phosphate Dehydrogenase by Estradiol

    Expression of GD Locus

    G6PD as a Tool and a Target for Studies on X-Chromosome Linkage

    X-Inactivation in Females Heterozygous for G-6-PD Variants

    Mechanism of Mammalian X-Chromosome Inactivation

    Insights into G6PD Regulation from Studies of X Dosage Compensation

    Polyclonal Tumors

    G-6-PD as a Marker for Tumors

    Glucose-6-Phosphate Dehydrogenase and Mosaic Analysis of Human Atherosclerotic Lesions

    Molecular Biology of Human G6PD

    Structure of Human Glucose-6-Phosphate Dehydrogenase

    Identification of a Reactive Lysine Residue in Human Erythrocyte Glucose-6-Phosphate Dehydrogenase

    Kinetics and Molecular Abnormalities of Human G6PD Variants

    Analysis of the Primary Structure of Human G6PD Deduced from the cDNA Sequence

    Molecular Cloning of cDNA for G6PD

    Poem

    Index




Product details

  • No. of pages: 552
  • Language: English
  • Copyright: © Academic Press 1986
  • Published: January 28, 1986
  • Imprint: Academic Press
  • eBook ISBN: 9780323146296

About the Editors

Akira Yoshida

Ernest Beutler

Affiliations and Expertise

Chairman, Department of Basic & Clinical Research; Head, Division of Hematology/Oncology, Scripps Clinic & Research Foundation, La Jolla, CA; Clinical Professor of Medicine, University of California, San Diego, CA

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