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Global Perspectives on Astaxanthin - 1st Edition - ISBN: 9780128233047, 9780128233054

Global Perspectives on Astaxanthin

1st Edition

From Industrial Production to Food, Health, and Pharmaceutical Applications

Editors: Gokare Ravishankar Ranga Ambati
Paperback ISBN: 9780128233047
eBook ISBN: 9780128233054
Imprint: Academic Press
Published Date: 9th April 2021
Page Count: 824
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Global Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applications explores the range of practical applications for this molecule, focusing on nutraceutical, pharmaceutical and cosmeceutical products, along with food and feed. This volume brings together the most relevant research, background and future thinking on astaxanthin, focusing on its health benefits. Chapters cover phytopharmaceuticals, industrial production, feeds, downstream processing, regulations, products, color, pigment, cosmetics, bioactive compounds, relationships to other carotenoids, and skin care. The detailed information on its production, processing, utilization and future applications will be of particular use to academic and industry researchers in pharmaceutical sciences, pharmacology and nutrition.

Key Features

  • Provides detailed information on astaxanthin, including its production, processing, utilization and future applications
  • Includes discussion on the commercial analysis procedure
  • Offers critical analysis on current and potential applications of astaxanthin as contributed by 121 authors from 22 countries in academia, research institutes and industries


Scientific researchers, entrepreneurs and the commercial bodies who are looking for new business opportunity or developing innovative bioproducts

Table of Contents

1. Synthesis of Astaxanthin Esters
Stanislav Vitalievich Pechinskii
2. The Physiology of Astaxanthin Production by Carotenogenic Microalgae
Alexei Solovchenko
3. Astaxanthin from Chromochloris zofingiensis: Feasibility Analysis
Dong Wei
4. Astaxanthin in Microalgae Eustigmatophyceae
Lília M.A. Santos
5. Astaxanthin Production by Autotrophic Cultivation of Haematococcus pluvialis-A Success Story
Ignacio Niizawa
6. Optimization of Astaxanthin Production Processes from Microalga Haematococcus
Jian Li
7. Production of Astaxanthin by Haematococcus pluvialis: Lab Processes to Scale Up Including The Cost Considerations
Miguel Daniel Noseda
8. Astaxanthin- Biological Production and Regulation for Enhanced Yields
Jiangxin Wang
9. Metabolic Engineering of Astaxanthin Pathway and Heterologous Production in Novel Organisms.
Sarada Ravi
10. Revealing Mechanisms of Algal Astaxanthin Production and Bioengineering Potential Using Multi-omics
Melissa Susan Roth
11. Astaxanthin production from Haematococcus pluvialis by using Illuminated photobioreactor
Yiu-Hang Ho
12. Recent Developments in Astaxanthin Production from Phaffia Rhodozyma and Its Applications
Ming-Jun Zhu
13. Turning Leftover to Treasure: An Overview of Astaxanthin from Shrimp Shell Wastes
Muskhazli Mustafa

14. Industrial Perspective on Downstream Processing of Haematococcus pluvialis Derived Astaxanthin for Incorporation in Food, Feed, And Nutraceuticals
Thomas O. Butler
15. Bio-Extraction of Astaxanthin Adopting Varied Techniques and Downstream Processing Methodologies
Xiang Cheng
16. Overview of Extraction of Astaxanthin From Haematococcus pluvialis Using CO2 Supercritical Fluid Extraction Technology Vis- A -Vis Quality Demands
Pradeep Verma
17. High-Pressure extraction of astaxanthin from Haematococcus pluvialis
MD Macias-Sánchez
18. Astaxanthin Extraction - Recent Methods, Developments and Case Studies
Hosahalli S. Ramaswamy

19. Efficacy of Astaxanthin from Different Sources: Reports on the Suitability for Human Health and Nutrition
Bob Capelli
20. Oxidation Products of Astaxanthin: An Overview
Takashi Maoka
21. Anticancer Properties of Astaxanthin: A Molecule of Great Promise
Pinar Buket Demirel, Bilge Guvenc Tuna
22. Astaxanthin for Improved Muscle Function and Enhanced Physical Performance
Karen A. Hecht, Ake Lignell and Arun Nair
23. Comprehensive Integrated Overview of the Experimental and Clinical Neuroprotective Effect of Astaxanthin
Samar S. Azab
24. Rheological properties of astaxanthin oleoresins and their derived products
Pedro Cerezal-Mezquita Sr.
25. Astaxanthin nanoparticles from fabrication to applications in food formulations including regulatory issues
Navideh Anarjan
26. Stability of Astaxanthin during Food Processing and Methods of Preservation
Reza Tahergorabi
27. Beneficial effects of Astaxanthin in Cosmeceuticals with Focus on Emerging Market Trends
Se-Kwon Kim
28. Safety Assessment and Pharmaceutical Effects of Astaxanthin: An Overview
Baskaran Vallikannan

29. Astaxanthin Production and Technology in Vietnam and Other Asian Countries
Dang Diem Hong
30. Utilization of Astaxanthin from Haematococcus for Its Use in Aquaculture and Poultry Industries
Gamze Turan
31. Astaxanthin from Bacteria as a Feed Supplement for Animals
Elena G. Kovaleva

32. Carotenoids Metabolic Pathways and Their Functional Role in Health and Diseases
Rangaswamy Lakshminarayanaa
33. Current Knowledge on the Health Benefits of Carotenoids: Focus on the Scientific Evidence
Delia B. Rodriguez-Amaya
34. Recent Updates on the Neuroprotective Role of Carotenoids: Astaxanthin and Beyond
Mohammad Hosein Farzaei and Eduardo Sobarzo-Sánchez
35. Stability Studies of Astaxanthin, Oleoresins and Emulsions in Products Developed For Human Consumption
Pedro Cerezal-Mezquita Sr.


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© Academic Press 2021
9th April 2021
Academic Press
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About the Editors

Gokare Ravishankar

Gokare A Ravishankar is presently the vice president of R&D in life Sciences and biotechnology at DayanandaSagar Institutions, Bengaluru, India; professor of biotechnology. Earlier he had a distinguished research career of over 30 years at the Central Food Technological Research Institute( CFTRI) , Mysuru and in the institutions of government of India. Served as chairman of board of studies in biotechnology at the Visvesvaraya Technological University, Belgavi, and Academic Council Member of DayanandaSagar University. He has also been member of the boards of eightuniversities. He is an internationally recognized expert in the areas of food science and technology, plant biotechnology, algal biotechnology, food biotechnology and post –harvest technologies, plant secondary metabolites, functional foods, herbal products , genetic engineering and biofuels and served as visiting professors to Universities in Japan, Korea, Taiwan and Russia. Dr Ravishankar holds a master’s and Ph.D degree from Maharaja Sayajirao University of Baroda. He mentored over 40 Ph.D students, 62 Masters students, 7 postdocs and 8 international guest scientists; authored over 260 peer-reviewed research papers in International and national journals, 50 reviews, 55 patents in India and abroad, edited 5 books , with a h-index of 63 and over 17,000 citations. He has presented over 220 lectures in various scientific meetings in India and abroad, including visits to over 25 countries. Dr Ravishankar received several coveted honors and awards as follows: Young Scientist award( Botany) by the then prime minister of India in 1992; National Technology Day Award of Government of India in 2003; LaljeeGoodhooSmarakNidhi Award for food biotechnology R&D of industrial relevance and the prestigious, professor V. Subramanyan Food- Industrial Achievement Award; Professor S.S.Katiyar Endowment Lecture Award in New Biology by Indian Science Congress; Professor Vyas Memorial Award of Association of Microbiologists of India; Professor V.N.RajaRao Endowment Lecture Award in Applied Botany,University of Madras; Lifetime achievement award by the Society of Applied Biotechnologists, DrDiwaker Patel Memorial award by Anand Agricultural University, Anand; Prof C.S.Paulose Memorial Oration Award by Society for Biotechnologists of India; Prof Gadgil Memorial Lecutre Award, Plant Tissue Culture Association of India, 2020. He is honoured as fellow of several national organizations in India viz. National Academy of Sciences; National Academy of Agricultural Sciences; Association of Microbiologists of India; Society of Agricultural Biochemists; Society of Applied Biotechnologists; Indian Botanical Society; and the Association of Food Scientists and Technologists of India. He is also elected member of Plant Tissue Culture Association of India. He has held honorary positions of President in Society of Biological Chemists, Mysore Chapter and President of Association of Microbiologists of India , Mysore and Bangalore Chapters. He is life member of Nutrition Society of India and several biotechnology societies including Society for Biotechnologists of India, Biotechnology Research Society of India, International Coffee Genome Network, American Society of Plant Biologists and Global Harmonization Initiative. He is a consultant to World Bank projects in the domains of postharvest technologies, plant biotechnologies for value addition to crop plants and food biotechnologies. He has also served as advisor and resource person in international conferences, seminars, workshops, short courses; and has convened national and international seminars in biology, biotechnology and food science & technology. He is an associate editor and reviewer in a large number of reputed research journals.

Affiliations and Expertise

C.D. Sagar Centre for Life Sciences, Dayananda Sagar College of Engineering and Dayananda Sagar University (Dayananda Sagar Institutions) , Kumaraswamy Layout, Bangalore, Karnataka, India

Ranga Ambati

Ambati RangaRao is a Senior Scientist & Associate Professor in the Department of Biotechnology at Vignan`s Foundation for Science, Technology and Research (Deemed to be University), Andhra Pradesh, India. Dr. Ranga Rao holds Bachelors and Masters degree from Acharya Nagarjuna University, Andhra Pradesh India and Ph.D degree from University of Mysore. He started his research career in 2004 as research assistant at the Department of Plant Cell Biotechnology, Council of Scientific and Industrial Research (CSIR)-Central Food Technological Research Institute (CFTRI), Mysuru, India under the supervision of Dr. G. A. Ravishankar and Dr. R. Sarada. He was awarded Senior Research Fellow of Indian Council of Medical Research (ICMR), New Delhi in the year 2007. His Ph.D work at CFTRI focused on Production of astaxanthin from cultured green alga Haematococcus pluvialis and its biological activities. He worked extensively on process optimization of algal biomass production; mass culture of various algal species in raceway ponds and photobioreactors; downstream processing of algal metabolites and evaluation of their possible nutraceutical applications in in vitro and in vivo models.Further Dr. Ranga Rao worked as Lead Scientist in Algal Technologies, Carot Labs Pvt Ltd-India; Postdoctoral Research Associate in Laboratory of Algal Research and Biotechnology, Arizona State University-USA under the supervision of Prof. Milton Sommerfeld and Prof. Qiang Hu; Visiting Assistant Professor in Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University, United International college, China under the supervision of Prof. Bo Lei; Visiting Senior Research Fellow (Associate Professor Grade) in Institute of Ocean and Earth Sciences, University of Malaya, Malaysia under the guidance of Prof. Phang Siew-Moi. He is the author of more than 40 peer-reviewed publications; 50 International/national conferences/symposia/invited talks, 10 chapters in books. His research citations exceed 2180 with h-index (16) and i10-index (20) as Google Scholar. He has delivered lectures at international/national conferences/symposia in USA, Canada, Brazil, China, Malaysia, Indonesia and Oman. He has edited two books (CRC Press, USA) as co-editor namely Handbook of Algal Technologies and Phytochemicals: Volume-I Food, Health and Nutraceutical Applications; and Handbook of Algal Technologies and Phytochemicals: Volume II Phycoremediation, Biofuels and Global Biomass Production. He was selected for Junior Scientist of the Year Award (2015) by National Environmental Science Academy, New Delhi, India; honored TWAS-Young Affiliate (2014) by Regional Office of East South-East Asia and the Pacific Chinese Academy of Sciences (CAS), China; received Young Scientist Award (2014) at the World Food Congress by International Union of Food Science and Technology (IUFoST), Canada; Carl Storm International Diversity Fellowship Award (2010) by Gordon Research Conferences, USA. He is an associate fellow of Andhra Pradesh Akademi of Sciences (2019) Government of Andhra Pradesh, India and also fellow of the Society of Applied Biotechnology (2013), India. He has received research grants and travel grant fellowship as both international and national awards, under Young Scientist schemes. He is also serving as editorial board member and reviewer for reputed international and national journals.

Affiliations and Expertise

Department of Biotechnology, Vignan’s Foundation for Science, Technology and Research (Deemed to be University), Vadlamudi, Guntur, Andhra Pradesh, India

Ratings and Reviews