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Global Perspectives on Astaxanthin - 1st Edition - ISBN: 9780128233047

Global Perspectives on Astaxanthin

1st Edition

From Industrial Production to Food, Health, and Pharmaceutical Applications

Editors: G.A. Ravishankar Ranga Ambati
Paperback ISBN: 9780128233047
Imprint: Academic Press
Published Date: 1st April 2021
Page Count: 695
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Global Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applications explores the range of practical applications for this molecule, focusing on nutraceutical, pharmaceutical and cosmeceutical products, along with food and feed. This volume brings together the most relevant research, background and future thinking on astaxanthin, focusing on its health benefits. Chapters cover phytopharmaceuticals, industrial production, feeds, downstream processing, regulations, products, color, pigment, cosmetics, bioactive compounds, relationships to other carotenoids, and skin care. The detailed information on its production, processing, utilization and future applications will be of particular use to academic and industry researchers in pharmaceutical sciences, pharmacology and nutrition.

Key Features

  • Provides detailed information on astaxanthin, including its production, processing, utilization and future applications
  • Includes discussion on the commercial analysis procedure
  • Offers critical analysis on current and potential applications of astaxanthin as contributed by 121 authors from 22 countries in academia, research institutes and industries


Scientific researchers, entrepreneurs and the commercial bodies who are looking for new business opportunity or developing innovative bioproducts

Table of Contents

Section 1: Astaxanthin from diverse sources: Industrial production
1. Astaxanthin from diverse algal sources
2. Biosynthesis of astaxanthin
3. Biosynthesis of astaxanthin and its esters
4. Chemical synthesis of astaxanthin and its esters
5. Astaxanthin: A comparative case of synthetic Vs. natural production
6. Astaxanthin from fungi and scaleup technology
7. Astaxanthin from bacterial sources and scaleup potential
8. Valorization of raw materials from agricultural industry for astaxanthin and ß-carotene production by Xanthophyllomyces dendrorhous
9. Astaxanthin from Xanthophyllomyces dendrorhous- Feasibility studies
10. Astaxanthin from Paracoccus haeundaensis sp- Large scale production
11. Astaxanthin from Yarrowia lipolytica- Scale up strategies
12. Astaxanthin from Phaffia rhodozyma:  Industrial production Process
13. Astaxanthin from Yeast: Industrial challenges
14. Astaxanthin from Haematococcus  pluvialis.: Global Industrial Production
15. Astaxanthin production from algae using Photobioreactors.
16. Maximization of Astaxanthin Production from Green Microalga Haematococcus pluvialis Using Internally-Illuminated Photobioreactor
17. Commercial astaxanthin production derived by green alga Haematococcus pluvialis: A microalgae process model and a techno-economic assessment all through production line
18. Life cycle assessment of the production of the red antioxidant carotenoid astaxanthin by microalgae: from lab to pilot scale
19. Astaxanthin in microalgae: pathway engineering and biotechnological implications;
20. Astaxanthin from Mangrove ecosystem
21. Astaxanthin from The Sea Urchin Arabacia lixula- Scale up strategies
22. Astaxanthin from Crustacean wastes: Industrial perspectives
23. Astaxanthin from seaweed and other marine algae- global scenario

Section 2:  Astaxanthin:Extraction, characterization, and downstream processing
24. Extraction of Astaxanthin from Green Alga Haematococcus pluvialis
25. Extraction of Astaxanthin from Haematococcus pluvialis Using Supercritical CO2 and Ethanol as solvents
26. Supercritical fluid extraction of astaxanthin from Haematococcus pluvialis
27. Astaxanthin from Engineered Camelina Sativa  coupled to  supercritical CO2 extraction
28. Hydrolytic efficiency and isomerization during de-esterification of natural astaxanthin esters by saponification and enzymolysis
29. Extraction of astaxanthin from microalga Haematococcus pluvialis in red phase by using generally recognized as safesolvents and accelerated extraction
30. Accurate quantification of astaxanthin from Haematococcus pluvialis using DMSO extraction and lipase-catalyzed hydrolysis pretreatment
31. Hydrothermal disruption of algae cells for astaxanthin extraction.
32. The efficiency and comparison of novel techniques for cell wall disruption in astaxanthin extraction from Haematococcus
33. Novel astaxanthin extraction from Haematococcus pluvialis
34. Breaking dormancy in algae : Energy efficient means of recovering astaxanthin
35. Cell wall disruption and lipid/astaxanthin extraction from microalgae 

Section 3:  Astaxanthin:  Food, Health and Medicinal Applications
36. Antioxidant Property of astaxanthin
37. Astaxanthin as medicinal food
38. Astaxanthin for Cosmetic Products
39. Ulcer properties of astaxanthin
40. Prevention of Oxidative stress and inflammation by Astaxanthin
41. Anti -Proliferative effects of astaxanthin
42. Anti cancer properties of astaxanthin
43. Antitumor activity of astxanthin and its mode of action
44. Anti-inflammatory effects of astaxanthin for oral health
45. Anti-inflammation activity of astaxanthin for health foods
46. Neuroprotective role of astaxanthin
47. Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration
48. Astaxanthin improves cognitive deficits from oxidative stress, nitric oxide synthase and inflammation through up-regulation of PI3K/Akt in diabetes rat
49. Astaxanthin effects related to the cardiovascular system
50. Potential Anti-Atherosclerotic Properties of Astaxnthin
51. Astaxanthin a novel potential treatment for oxidative stress and inflammation in cardiovascular disease
52. Asaxanthin-Metabolism, Bioavailability and crossing of blood brain barrier
53. Effects of astaxanthin on skin health. Department of Medicine and Health Sciences
54. The Protective Role of Astaxanthin for UV-Induced Skin Deterioration
55. Prevention of  skin deterioration by astaxanthin
56. Anti-anxiety properties of astaxanthin
57. Antioxidant effects of astaxanthin in various diseases
58. Effects of astaxanthin on Gastric inflammatory disorder
59. Anti-diabetic Property of astxanthin
60. Anti-diabetic property of  astaxanthin in diabetic rats
61. Astaxanthin for eye health
62. Influence of dietary astaxanthin for eye health
63. Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food
64. Astaxanthin inhibits reactive oxygen species mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism
65. Astaxanthin as  food colorant : Safety and regulatory issues
66. Scientific Opinion on the safety of astaxanthin-rich ingredients as novel food ingredients
67. Astaxanthin based Nutraceutical products
68. Astaxanthin in  sports health
69. Astaxanthin in Sports Nutrition
70. Dietary Astaxanthin for improved Strength endurance
71. Astaxanthin for animal feed – industrial perspectives
72. Astaxanthin as anti-aging agent in specialty products


No. of pages:
© Academic Press 2021
1st April 2021
Academic Press
Paperback ISBN:

About the Editors

G.A. Ravishankar

Gokare A Ravishankar is presently the vice president of R&D in life Sciences and biotechnology at DayanandaSagar Institutions, Bengaluru, India; professor of biotechnology. Earlier he had a distinguished research career of over 30 years at the Central Food Technological Research Institute( CFTRI) , Mysuru and in the institutions of government of India. Served as chairman of board of studies in biotechnology at the Visvesvaraya Technological University, Belgavi, and Academic Council Member of DayanandaSagar University. He has also been member of the boards of eightuniversities. He is an internationally recognized expert in the areas of food science and technology, plant biotechnology, algal biotechnology, food biotechnology and post –harvest technologies, plant secondary metabolites, functional foods, herbal products , genetic engineering and biofuels and served as visiting professors to Universities in Japan, Korea, Taiwan and Russia. Dr Ravishankar holds a master’s and Ph.D degree from Maharaja Sayajirao University of Baroda. He mentored over 40 Ph.D students, 62 Masters students, 7 postdocs and 8 international guest scientists; authored over 260 peer-reviewed research papers in International and national journals, 50 reviews, 55 patents in India and abroad, edited 5 books , with a h-index of 63 and over 17,000 citations. He has presented over 220 lectures in various scientific meetings in India and abroad, including visits to over 25 countries. Dr Ravishankar received several coveted honors and awards as follows: Young Scientist award( Botany) by the then prime minister of India in 1992; National Technology Day Award of Government of India in 2003; LaljeeGoodhooSmarakNidhi Award for food biotechnology R&D of industrial relevance and the prestigious, professor V. Subramanyan Food- Industrial Achievement Award; Professor S.S.Katiyar Endowment Lecture Award in New Biology by Indian Science Congress; Professor Vyas Memorial Award of Association of Microbiologists of India; Professor V.N.RajaRao Endowment Lecture Award in Applied Botany,University of Madras; Lifetime achievement award by the Society of Applied Biotechnologists, DrDiwaker Patel Memorial award by Anand Agricultural University, Anand; Prof C.S.Paulose Memorial Oration Award by Society for Biotechnologists of India; Prof Gadgil Memorial Lecutre Award, Plant Tissue Culture Association of India, 2020. He is honoured as fellow of several national organizations in India viz. National Academy of Sciences; National Academy of Agricultural Sciences; Association of Microbiologists of India; Society of Agricultural Biochemists; Society of Applied Biotechnologists; Indian Botanical Society; and the Association of Food Scientists and Technologists of India. He is also elected member of Plant Tissue Culture Association of India. He has held honorary positions of President in Society of Biological Chemists, Mysore Chapter and President of Association of Microbiologists of India , Mysore and Bangalore Chapters. He is life member of Nutrition Society of India and several biotechnology societies including Society for Biotechnologists of India, Biotechnology Research Society of India, International Coffee Genome Network, American Society of Plant Biologists and Global Harmonization Initiative. He is a consultant to World Bank projects in the domains of postharvest technologies, plant biotechnologies for value addition to crop plants and food biotechnologies. He has also served as advisor and resource person in international conferences, seminars, workshops, short courses; and has convened national and international seminars in biology, biotechnology and food science & technology. He is an associate editor and reviewer in a large number of reputed research journals.

Affiliations and Expertise

C.D. Sagar Centre for Life Sciences, Dayananda Sagar College of Engineering and Dayananda Sagar University (Dayananda Sagar Institutions) , Kumaraswamy Layout, Bangalore, Karnataka, India

Ranga Ambati

Ambati RangaRao is a Senior Scientist & Associate Professor in the Department of Biotechnology at Vignan`s Foundation for Science, Technology and Research (Deemed to be University), Andhra Pradesh, India. Dr. Ranga Rao holds Bachelors and Masters degree from Acharya Nagarjuna University, Andhra Pradesh India and Ph.D degree from University of Mysore. He started his research career in 2004 as research assistant at the Department of Plant Cell Biotechnology, Council of Scientific and Industrial Research (CSIR)-Central Food Technological Research Institute (CFTRI), Mysuru, India under the supervision of Dr. G. A. Ravishankar and Dr. R. Sarada. He was awarded Senior Research Fellow of Indian Council of Medical Research (ICMR), New Delhi in the year 2007. His Ph.D work at CFTRI focused on Production of astaxanthin from cultured green alga Haematococcus pluvialis and its biological activities. He worked extensively on process optimization of algal biomass production; mass culture of various algal species in raceway ponds and photobioreactors; downstream processing of algal metabolites and evaluation of their possible nutraceutical applications in in vitro and in vivo models.Further Dr. Ranga Rao worked as Lead Scientist in Algal Technologies, Carot Labs Pvt Ltd-India; Postdoctoral Research Associate in Laboratory of Algal Research and Biotechnology, Arizona State University-USA under the supervision of Prof. Milton Sommerfeld and Prof. Qiang Hu; Visiting Assistant Professor in Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University, United International college, China under the supervision of Prof. Bo Lei; Visiting Senior Research Fellow (Associate Professor Grade) in Institute of Ocean and Earth Sciences, University of Malaya, Malaysia under the guidance of Prof. Phang Siew-Moi. He is the author of more than 40 peer-reviewed publications; 50 International/national conferences/symposia/invited talks, 10 chapters in books. His research citations exceed 2180 with h-index (16) and i10-index (20) as Google Scholar. He has delivered lectures at international/national conferences/symposia in USA, Canada, Brazil, China, Malaysia, Indonesia and Oman. He has edited two books (CRC Press, USA) as co-editor namely Handbook of Algal Technologies and Phytochemicals: Volume-I Food, Health and Nutraceutical Applications; and Handbook of Algal Technologies and Phytochemicals: Volume II Phycoremediation, Biofuels and Global Biomass Production. He was selected for Junior Scientist of the Year Award (2015) by National Environmental Science Academy, New Delhi, India; honored TWAS-Young Affiliate (2014) by Regional Office of East South-East Asia and the Pacific Chinese Academy of Sciences (CAS), China; received Young Scientist Award (2014) at the World Food Congress by International Union of Food Science and Technology (IUFoST), Canada; Carl Storm International Diversity Fellowship Award (2010) by Gordon Research Conferences, USA. He is an associate fellow of Andhra Pradesh Akademi of Sciences (2019) Government of Andhra Pradesh, India and also fellow of the Society of Applied Biotechnology (2013), India. He has received research grants and travel grant fellowship as both international and national awards, under Young Scientist schemes. He is also serving as editorial board member and reviewer for reputed international and national journals.

Affiliations and Expertise

Department of Biotechnology, Vignan’s Foundation for Science, Technology and Research (Deemed to be University), Vadlamudi, Guntur, Andhra Pradesh, India

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