Key Features

  • Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers.
  • Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians.
  • Diagnose AIDS manifestations confidently by comparing them to full-color clinical images.
  • Review essential data quickly through numerous at-a-glance tables.

Table of Contents

I. The Common Core of HIV Management

A. World-Wide HIV Epidemiology

B. The Virology of HIV Infection

1. Molecular insights into HIV Infection & Pathogenesis

2. Biology of ARV Targets & Mechanism of Action

3. Biology of ART Resistance, Repletive Capacity & Biological Fitness

C. HIV & the Immune System:

1. Immuno-pathogenesis & CD4 Kinetics

2. Immune Response to HIV; CTLs & HIV

3. Consequences of Immune Recovery from ART

D. Biology of HIV Transmission

E. Vaccine Development

II. The Treatment of HIV Infection

A. Natural History of HIV Infection

B. Laboratory Testing for HIV

C. Goals of ART

D. ART Drugs

1. Structure

2. Mechanism of action

3. Toxicity

4. Drug-drug interactions

5. Monitoring therapy

III. Diseases of HIV Infection

A. Organs Affected by HIV

1. Oral complications of HIV

2. Ocular complications of HIV

3. Dermatological complications of HIV

4. Gastrointestinal & hepatic manifestations of HIV

5. Neurological manifestations of HIV

6. Psychiatric manifestations of HIV

7. Hematological manifestations of HIV

8. Cardiovascular complications of HIV

9. Endocrine manifestations of HIV

10. Renal complications of HIV

B. Specific Infections & Malignancies in HIV

1. Pneumocystis pneumonia

2. Other HIV-related pulmonary infections

3. Mycobacterium avium complex & other atypical mycobacterial infections

4. Tuberculosis in the HIV-infected patient

5. Cryptococcosis

6. Histoplasmosis & Blastomycosis

7. Coccidioidomycosis

8. Penicilliosis

9. Candida infections

10. Toxoplasmosis

11. Hepatitis B & C in HIV-infected patients

12. Bacillary angiomatosis and other unusual bacterial infect


No. of pages:
© 2008
Print ISBN:

About the editors

Paul Volberding

Affiliations and Expertise

Professor and Vice-Chair of Medicine, UCSF; Chief, Medical Service, San Francisco Veterans Affairs Medical Center; Co-Director, UCSF-GIVI Center for AIDS Research, San Francisco, CA, USA

Merle Sande

Affiliations and Expertise

Professor, Department of Medicine, Co-Chair of the Academic Alliance for AIDS Care in Africa, University of Utah, Salt Lake City, UT, USA

Joep Lange

Affiliations and Expertise

Professor of Medicine; Global Health; Academic Medical Center, University of Amsterdam; Amsterdam Institute for Global Health and Development; Amsterdam; The Netherlands

Warner Greene

Affiliations and Expertise

Director, Gladstone Institute of Virology and Immunology, University of California-San Francisco, San Francisco, CA, USA

Joel Gallant

Affiliations and Expertise

Professor of Medicine and Epidemiology;Associate Director, Johns Hopkins AIDS Service;Division of Infectious Diseases, Department of Medicine;Johns Hopkins University School of Medicine;Baltimore, MD, USA