Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America

1st Edition, Volume 32-1 - November 23, 2020
Editor: Michael A Vogelbaum
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 9 0 9 4 - 9
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 9 0 9 5 - 6

This issue of Neurosurgery Clinics, guest edited by Dr. Michael A. Vogelbaum, is devoted to Glioblastoma, Part I: Surgical Management and Adjuncts. This is one of four issues… Read more

Glioblastoma, Part I: Surgical Management and Adjuncts, An Issue of Neurosurgery Clinics of North America

Purchase options

Info / Buy

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Institutional subscription on ScienceDirect

Request a sales quote

This issue of Neurosurgery Clinics, guest edited by Dr. Michael A. Vogelbaum, is devoted to Glioblastoma, Part I: Surgical Management and Adjuncts. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue include: Perioperative Management of Patients with Glioblastoma, Role of Resection in Glioblastoma Management, Advancing Imaging to Enhance Surgery, Intraoperative Imaging for High-Grade Glioma Surgery, Use of Intraoperative Fluorophores, Extent of Resection of Glioblastoma, Functional Mapping for Glioma Surgery: Preoperative Mapping Tools, Functional Mapping for Glioma Surgery: Intraoperative Mapping Tools, Surgical Adjuncts for Glioblastoma, Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors, Stereotactic Laser Ablation of Glioblastoma, Radiosurgery for Glioblastoma, Challenges Associated with Reoperation in Patients with Glioma, and Surgery for Glioblastoma in Elderly Patients.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Perioperative Management of Patients with Glioblastoma
Key points
Introduction
Discussion
Seizures in glioblastoma patients
Rehabilitation
Adjuvant therapies
Summary
Clinics care points
Role of Resection in Glioblastoma Management
Key points
Introduction
Measuring and predicting extent of resection
Methods for optimizing extent of resection
Relationship between extent of resection and survival
Mechanisms by which extent of resection might affect survival
Preoperative assessment of resectability
Role of resectability in clinical trials
Measuring resectability
Summary and further considerations
Clinics care points
Extent of Resection of Glioblastoma: A Critical Evaluation in the Molecular Era
Key points
Introduction
Diagnostic accuracy
Therapeutic cytoreduction
Summary
Clinics care points
Advancing Imaging to Enhance Surgery: From Image to Information Guidance
Key points
Introduction
Current evidence
Clinical relevance
Advanced imaging for improving information guidance
Discussion
Final remarks
Clinics care points
Intraoperative Imaging for High-Grade Glioma Surgery
Key points
Intraoperative imaging
Intraoperative ultrasound
Intraoperative MRI
Laser interstitial thermal therapy
Intraoperative computed tomography
Summary
Clinics care points
Use of Intraoperative Fluorophores
Key points
Introduction
Principles of fluorescent-guided surgery
Fluorescein sodium fluorescent-guided surgery
Indocyanine green
Targeted fluorophores
Visualization technologies
Summary
Clinics care points
Supplementary data
Functional Mapping for Glioma Surgery, Part 1: Preoperative Mapping Tools
Key points
Introduction
Functional magnetic resonance imaging
Magnetoencephalography
Navigated transcranial magnetic stimulation
Tractography
Discussion
Summary
Clinics care points
Functional Mapping for Glioma Surgery, Part 2: Intraoperative Mapping Tools
Key points
Introduction
Sensorimotor mapping
Language mapping
Nonlanguage cognitive mapping
Management of intraoperative complications associated with mapping
Summary and future directions
Clinics care points
Surgical Adjuncts for Glioblastoma
Key points
Introduction
Discussion
Summary
Clinics care points
Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors
Key points
Introduction
Defining features of a window of opportunity trial
Incorporating window of opportunity trials into early phase trials of brain tumors
Summary
Clinics care points
Stereotactic Laser Ablation of Glioblastoma
Key points
Introduction
Surgical methodology
Discussion
Summary
Radiosurgery for Glioblastoma
Key points
Introduction
Stereotactic radiosurgery technique
Stereotactic radiosurgery for recurrent glioblastoma
Upfront and boost stereotactic radiosurgery
Leading edge stereotactic radiosurgery
Stereotactic radiosurgery and bevacizumab
Molecular profiles and stereotactic radiotherapy
Summary
Clinics care points
Challenges Associated with Reoperation in Patients with Glioma
Key points
Background
Indications for reoperation and surgical goals
Practical challenges during reoperation
Summary
Clinics care points
Surgery for Glioblastoma in Elderly Patients
Key points
Introduction and background
Current evidence
Summary
Clinics care points

Purchase options

Save 50% on book bundles

Institutional subscription on ScienceDirect

Michael A Vogelbaum