Germ Cell Tumours III

Germ Cell Tumours III

Proceedings of the Third Germ Cell Tumour Conference Held in Leeds, UK, on 8th—10th September 1993

1st Edition - January 1, 1994

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  • Editors: W.G. Jones, P. Harnden, I. Appleyard
  • eBook ISBN: 9781483278384

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Advances in the Biosciences, Volume 91: Germ Cell Tumours III documents the proceedings of the Third Germ Cell Tumor Conference held in Leeds, UK on September 8-10, 1993. This book focuses on germ cell tumors, which can be cancerous or non-cancerous tumors that normally occur inside the gonads. The topics discussed include the embryological mechanisms of maldescent and tumorigenesis; epidemiology of cryptorchidism; simultaneous bilateral testicular tumors; and mediastinal germ cell tumors. The classification of germ cell tumors; role of positron emission tomography in the assessment of germ cell tumors; chemotherapy of seminoma; and prognostic factors in disseminated non-seminomatous testicular cancer are also elaborated in this text. This publication is intended for medical students and individuals interested in germ cell tumors.

Table of Contents

  • Embryological Mechanisms of Maldescent and Tumorigenesis

    The Epidemiological Association between Undescended Testis, Inguinal Hernia and Testicular Cancer: Results from the U.K. National Case-Control Study of Testicular Cancer

    The Epidemiology of Cryptorchidism: Results from the John Radcliffe Hospital Cryptorchidism Study

    Maldescent and Cryptorchidism: A Rational Approach to Management

    Recent Progress in Research on CIS in Adults. Biological Aspects and Screening

    Simultaneous Bilateral Testicular Tumors

    Are Pediatric Germ Cell Tumors Germ Cell Tumors?

    Pathology and Cytogenetics of Germ Cell Tumors in Children

    UKCCSG Studies of Pediatric Germ Cell Tumors

    Changing Pattern of Incidence and Survival in Children with Germ Cell Tumors (GCTs)

    Testicular Non-Seminomatous Germ Cell Tumor (TGMnS) French Society of Pediatric Oncology Experience (SFOP), 1985-1989

    Chemotherapy Associated Toxicity in Patients with Malignant Non Testicular Germ Cell Tumors (MNGCTs). Comparison of MAKEI 83/86 and MAKEI 89

    Germ Cell Tumors in Children: A Report of 84 Cases

    Pediatric Germ Cell Tumors in the West Midlands Health Authority Region (WMHAR): Increasing Incidence and Pattern of Geographical Distribution

    Gonadotrophin and Sex Hormone Levels in Testis Cancer Patients with and without Carcinoma In Situ of the Contralateral Testis

    Contralateral Biopsies in Patients with Testicular Germ Cell Tumor - The German Experience

    Seminal Fluid Analysis and Carcinoma-In-Situ of the Testis

    Abdominal CT Scans in Patients with Retroperitoneal Germ Cell Tumors with or without Carcinoma In Situ

    The Value of Testicular Biopsy as a Screening Procedure for Future Malignant Germ Cell Tumors in Infertile Men

    Inter-phase Cytogenetics of Testicular Germ Cell Tumors: Clonal

    Origin of Seminoma and Nonseminoma Components in Combined Tumors

    Growth of Human Seminoma Cells on STO Feeder Depends on Phenotype, Presence of Fetal Calf Serum and Added Growth Factors

    Molecular Genetics in Germ Cell Tumors

    Mediastinal Germ Cell Tumors

    The Origin of Non-Germ Cell Tumor Elements within Germ Cell

    Unusual Neoplasms Detected in Testis Cancer Patients Undergoing Post Chemotherapy Retroperitoneal Lymphadenectomy

    Outcome Analysis for Patients with Persistent Non-Seminomatous Germ Cell Tumor in Post-Chemotherapy Retroperitoneal Lymph Node Dissections

    The Wilms' Tumor 1 Gene in Testicular Cancer Patients

    Image Analysis Quantitation of P53 Gene Product and Ki-67 in Testicular Germ Cell Tumors - A Quantitative Immunohistochemical Study

    Is Apoptosis an Important Mode of Death in Embryonal Carcinoma?

    Growth Inhibition and Differentiation of a Human Embryonal

    Carcinoma (EC) Cell Line by Osteogenic Protein-1 (OP-1)

    Revised International Histological Classification of Testicular Tumors

    New Classification of Germ Cell Tumors

    Discussion on the Classification of Germ Cell Tumors

    Grading Germ Cell Tumors as a Means to Resolve the Last Twenty Five Years Transatlantic Conflict over Testis Tumor Classification

    The Clinical Value of Imaging Germ Cell Tumors with Radiolabeled Antibodies

    The Role of Positron Emission Tomography in the Assessment of Germ Cell Tumors

    The Princess Margaret Hospital Experience in the Management of Stage I and II Seminoma - 1981 to 1991

    Chemotherapy of Seminoma

    Late Relapse in Patients on Surveillance for Stage I Testicular Seminoma

    Surveillance of Stage I Non-Seminomatous Testicular Cancer - A Preliminary Report of the EORTC GU-Cooperative Group Surveillance Study

    Short Course Adjuvant Chemotherapy in High Risk Stage I Non-Seminomatous Germ Cell Tumors of the Testis (NSGCTT): An MRC Study Report

    One Course Adjuvant Treatment for Stage 1 Germ Cell Tumors

    NSGCT Stage I - Adjuvant Chemotherapy for Patients with Vascular Invasion and Surveillance for Patients without Vascular Invasion: Update of a Prospective Trial after 8 Years

    Testicular Cancer in Russia

    Good Risk Chemotherapy Trials for Patients with Advanced Germ Cell Tumors: The MSKCC Experience

    Carboplatin-Based Chemotherapy in Good Prognosis Metastatic Non-Seminoma of the Testis (NSGCT): An Interim report of an MRC/EORTC Randomized Trial

    Insurance Status as a Prognostic Factor for Stage and Survival of Testicular Cancer Patients in Illinois

    Prognostic Factors in Metastatic Seminoma and Non-Seminomatous Germ Cell Tumors

    Prognostic Factors in Disseminated Non-Seminomatous Testicular Cancer

    Predictors of Residual Mass Histology Following Chemotherapy for Metastatic Nonseminomatous GCT: Univariate and Multivariate Meta-Analysis

    Resection of Small Masses of Residual NSGCT and Subsequent Therapy: Dilemmas in Clinical Decision Making

    Needs, Findings and Outcome of Post-Chemotherapy Surgery of Residual Masses (RM) in Patients with Non-Seminomatous Germ Cell Testis Tumors (NSGCTT) at a Single Institution

    Treatment of Brain Metastases Round Table

    Treatment of Central Nervous System (CNS) Metastases of Non-Seminomatous Germ Cell Tumors: The Charing Cross Experience

    Treatment of Cerebral Metastases from Malignant Germ Cell Tumor

    Management of Central Nervous System Metastases in Patients with Disseminated Germ Cell Tumors

    The Treatment of Brain Metastases from Germ Cell Cancer - A Report of the Round-Table Discussion

    Dose Intensive Chemotherapy for Poor Prognosis Germ Cell Malignancies

    Schedule Intensive Treatment for Testicular Germ Cell Tumors

    Salvage Therapy in Metastatic Non-Seminomatous Germ Cell Tumor at the University of Texas M. D. Anderson Cancer Center

    Late Relapses in Advanced Malignant Germ Cell Tumors (MGCT) Treated with Cisplatin Based Chemotherapy

    The Importance of Dose Intensity in the Chemotherapy of Advanced Testicular Cancer

    Salvage Chemotherapy and ABMT Round Table

    Salvage Chemotherapy and Autologous Bone Marrow Transplantation: 9-Year Experience at Institute Gustave-Roussy

    Dose-Intensive Chemotherapy in Patients with Germ Cell Tumors: The Memorial Sloan-Kettering Cancer Center Experience

    A High-Dose Carboplatin-Based Salvage Strategy for Relapsing or Refractory Germ Cell Cancer

    High Dose Chemotherapy with Autologous Marrow Rescue for Germ Cell Salvage Consolidation: Vancouver Experience

    Management of Recurrent Germ Cell Tumors: Role of High Dose Chemotherapy

    High Dose Chemotherapy with Hemopoietic Stem Cell Support

    Salvage Chemotherapy and Autologous Bone Marrow Chemotherapy for Refractory Germ Cell Malignancies

    High Dose Chemotherapy Plus Stem Cell Support for Poor Risk Testicular Cancer or as Salvage Therapy for Patients with Relapsed Disease

    Salvage Chemotherapy and Autologous Stem Cell/Bone Marrow Transplantation in Germ Cell Cancer - Summary of Papers Presented and Round-Table Discussion

    Surgery in Non-Seminomatous Germ Cell Tumors of the Testis

    Aortic Replacement in Retroperitoneal Lymph Node Dissection for Metastatic Germ Cell Cancer

    Resection of the Inferior Vena Cava or Intraluminal Tumor Thrombectomy during Retroperitoneal Lymph Node Dissection for Metastatic Germ Cell Cancer: Indications and Results

    Retroperitoneal Surgery: Management Strategies in Malignant Teratoma

    Modified Retroperitoneal Lymph Node Dissection for Testicular Tumor: Open and Laparoscopic Approach, Operative Technique and Results

    Late Side Effects in Patients Treated for Testicular Cancer

    Fertility in Nerve-Sparing RPLND

    Treatment for Loss of Ejaculation after Para-Aortic Lymphadenectomy

    Second Cancer Risk Following Testicular Cancer

    Long-Term Toxicity after Cisplatinum-Based Chemotherapy

    Experience of a Testicular Cancer Patient Support Group

    Severe Vascular Side Effects of Cisplatinum Based Chemotherapy

    Hemopoietic Growth Factors: An Overview

    Development of New Antiemetics

    Strategies to Control Vomiting Caused by Anticancer Drugs

    Chemotherapy for Testicular Cancer: Prophylactic Ciprofloxacin Reduces the Incidence of Neutropenic Pyrexia

    Germ Cell Tumors: Past, Present and Future

    Abstracts of Poster Presentations

    Is there any Relationship between Vasectomy and Testicular Cancer?

    Primary Cerebral Germinoma in Children - French Society of Pediatric Oncology (SFOP) Experience

    NSGCTT Metastases

    A Pilot Evaluation of Peripheral Blood Stem Cell Transplants Compared to ABMT following High Dose Chemotherapy

    Clinical Features and Prognosis of Primary Mediastinal and Retroperitoneal Germ Cell Tumors Treated with Cisplatin-Based Chemotherapy

    Four Drug Combination Chemotherapy Consisting of Etoposide, Cisplatin, Bleomycin and Cyclophosphamide for Advanced Metastatic Non-Seminomatous Germ Cell Tumors

    Germ Cell Tumors and Carcinoma In Situ of the Testis Detected by Fine Needle Biopsy

    Malignant Sex Cord/Stromal Tumors: A Case Report of a Metastatic Sertoli-Leydig Cell Tumor of the Testis

    Phase III Trial of Early Intensified Chemotherapy (HDCT) with Autologous Bone Marrow Transplantation (ABMT) in First Line Treatment of Poor Risk Non-Seminomatous Germ Cell Tumors (NSGCT): Long Term Results of a Randomized Trial

    Estimation of 12p Copy Number in Paraffin-Embedded Tissue Sections of Germ Cell Tumors by In Situ Hybridization of a Microdissected 12p Probe

    An Evolution of a Testicular Self-Examination Video

    High Dose Chemotherapy with Autologous Bone Marrow Transplantation for Advanced Germ Cell Tumors

    Localized Gonadal Non-Seminomatous Germ Cell Tumors - French Society of Pediatric Oncology Experience (SFOP)

    Salvage Therapy in Refractory/Relapsed Germ Cell Tumors: Etoposide, Ifosfamide and Cisplatin (VIP)

    Preliminary Results of BOP-VIP Protocol in Poor Risk "Worst Prognosis" Non-Seminomatous Germ Cell Tumors of Testis

    Cancer in Cryptorchid Testes at IRCH All India Institute of Medical Sciences, New Delhi 1987-1992

    Weekly Cisplatinum Combination Chemotherapy Regimes for Relapsed/Poorly Responding Metastatic Malignant Germ Cell Tumors

    The Results of a Surveillance Study in Stage I Non-Seminomatous Germ Cell Tumors of the Testis

    HCG Positive Seminoma


Product details

  • No. of pages: 480
  • Language: English
  • Copyright: © Pergamon 1994
  • Published: January 1, 1994
  • Imprint: Pergamon
  • eBook ISBN: 9781483278384

About the Editors

W.G. Jones

P. Harnden

I. Appleyard

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