
GERD
A New Understanding of Pathology, Pathophysiology, and Treatment
Description
Key Features
- Provides a new method of assessment of GERD that has never previously been presented, creating a pathway to control
- Describes a new pathologic test based on standard histology that can define lower esophageal sphincter damage
- Sequential chapters outline the way GERD progresses from the perspective of the amount of damage to the lower esophageal sphincter
- Provides new avenues of clinical research and technologic innovations in pathology and treatment aimed at preventing esophageal adenocarcinoma
Readership
Basic scientists, internists, gastroenterologists, foregut surgeons, and pathologists (general and GI)
Table of Contents
1. Definition of Gastroesophageal Reflux Disease: Past, Present and Future
2. Present Diagnosis and Management of Gastroesophageal Reflux Disease: The Good, Bad and Ugly
3. Fetal and Postnatal Development of the Esophagus and Proximal Stomach
4. Histologic Definition and Diagnosis of Epithelia in the Esophagus and Proximal Stomach
5. Definition of the Normal State – A Yet Unfinished Saga
6. Definition of the Gastroesophageal Junction
7. The Normal Lower Esophageal Sphincter
8. The Pathogenesis of Early GERD
9. Correlation of LES Damage and GERD
10. The Effect of Damage to the Abdominal Segment of the LES: The Dilated Distal Esophagus
11. Columnar-Lined Esophagus (Microscopic and Visible) and Barrett Esophagus
12. Esophageal Adenocarcinoma
13. Progression of GERD at the Clinical Level
14. Progression of GERD at a Pathological Level
15. Molecular Evolution of Esophageal Epithelial Metaplasia
16. Progression of GERD From the Perspective of LES Damage
17. New Pathologic Test of LES Damage
18. New Method of Functional Assessment of the LES
19. Prediction of Future Progression of LES Damage
20. Proof of Concept of the New Diagnostic Method
21. Application of the New Method to Present and Future Management of GERD
Product details
- No. of pages: 652
- Language: English
- Copyright: © Academic Press 2017
- Published: October 26, 2017
- Imprint: Academic Press
- eBook ISBN: 9780128098561
- Hardcover ISBN: 9780128098554
About the Author
Parakrama Chandrasoma
