Genomic and Precision Medicine

Genomic and Precision Medicine

Infectious and Inflammatory Disease

3rd Edition - August 15, 2019

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  • Editors: Geoffrey Ginsburg, Huntington Willard, Chris Woods, Ephraim Tsalik
  • eBook ISBN: 9780128015582
  • Hardcover ISBN: 9780128014967

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Description

Genomic and Precision Medicine: Infectious and Inflammatory Disease, Third Edition, provides current clinical solutions on the application of genome discovery on a broad spectrum of disease categories in IMD - including asthma, obesity and multiple sclerosis. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies, along with information on a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.

Key Features

  • Offers comprehensive coverage of infectious and inflammatory disease genomics
  • Provides succinct commentary and key learning points to assist providers with the implementation of genomic and personalized medicine
  • Presents an up-to-date overview on major opportunities for genomic and personalized medicine
  • Includes case studies that highlight the practical use of genomics in the management of patients

Readership

Medical students, life sciences and engineering graduate students, advanced undergraduate students, and residents and fellows working with any aspect of genomic research in the life sciences and/or medicine; educators and translational scientists

Table of Contents

  • 1. Overview:  Genome wide approaches to Inflammatory and Metabolic disease
    2. Application of Human Genome Information to Clinical Practice
    • Genome sequencing: new technologies, approaches, applications
    • Clinical applications of whole-genome chromosomal microarray analysis
    • Transcriptomics in the age of ultra high-throughput sequencing
    • Quantitative Proteomics in Genomic Medicine
    3. Translating genome information into clinical practice and human health
    4. Big Data and Translational Bioinformatics Genomic and Personalized Medicine
    • Biospecimen Banking linked to phenotype data
    • Electronic Health Records
    • Data Sharing and Privacy
    5. Health Risk Assessment and Family History
    6. Clinical Decision Support
    7. Overview of Policy, Ethical and Social Considerations
    8. Autoimmune Disorders
    9. Rheumatoid Arthritis
    10. Multiple Sclerosis
    11. Inflammatory Bowel Disease
    12. Asthma
    13. Chronic Obstructive Pulmonary Disease
    14. Interstitial Lung Disease
    15. Peptic Ulcer Disease
    16. Cirrhosis
    17. Systemic Sclerosis
    18. Lupus
    19. Osteoarthritis
    20. Diabetes Genomics
    21. The Metabolic Syndrome
    22. Approaching Obesity
    • The Microbiome and obesity
    23. Case Studies

Product details

  • No. of pages: 480
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: August 15, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128015582
  • Hardcover ISBN: 9780128014967

About the Editors

Geoffrey Ginsburg

Dr. Ginsburg is the founding Director of the Center for Applied Genomics & Precision Medicine in the Duke Institute for Genome Sciences & Policy. He is also Professor of Medicine and of Pathology at Duke University Medical Center, Professor of Biomedical Engineering at Duke Pratt School of Engineering, and Co-Director of the Duke Translational Medicine Institute.

Affiliations and Expertise

Chief Medical and Scientific Officer, All of Us Research Program, National Institutes of Health, Bethesda, Maryland, USA

Huntington Willard

Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.

Affiliations and Expertise

Chief Scientific Officer, Genome Medical, Inc., South San Francisco, CA, USA

Chris Woods

Affiliations and Expertise

Professor of Medicine and Global Health, Duke Center for Applied Genomics & Precision Medicine, Duke University School of Medicine; Chief, Infectious Disease Division, Durham VA Health Care System, USA

Ephraim Tsalik

Dr. Tsalik obtained his MD and PhD at Columbia University before coming to Duke for his clinical training in Internal Medicine followed by fellowship in Infectious Diseases. He is currently an Associate Professor of Medicine, Associate Professor of Molecular Genetics and Microbiology, and is a Physician in the Emergency Department at the Durham VA Health Care System. He is also Associate Director of Diagnostics for the Antibacterial Resistance Leadership Group. His research focuses on the host response to infection with a particular emphasis on translation to diagnostic tests.

Affiliations and Expertise

Duke Center for Applied Genomics & Precision Medicine, Duke University School of Medicine; Emergency Department Service, Durham VA Health Care System, USA.

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