Genetics of Bacterial Diversity

Genetics of Bacterial Diversity

1st Edition - December 1, 1988

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  • Editors: David A. Hopwood, Keith F. Chater
  • eBook ISBN: 9781483273556

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Genetics of Bacterial Diversity focuses on the rapidly developing field of ""non-K-12"" bacterial genetics that is largely outside the scope of other texts. The book begins with an introductory chapter that outlines the phylogenetic relationships of bacteria and the range of metabolic, behavioral, and developmental phenomena displayed by them. Two chapters then review the genetic processes found in bacteria generally, and discuss a range of genetic techniques used to analyze the various special systems described in the body of the book, respectively. Subsequent chapters deal with various special metabolic capabilities characteristic of certain groups of bacteria (light production, photosynthesis, nitrogen fixation, antibiotic production, degradation of aromatic compounds and mercury resistance); developmental processes of cell-cycle associated motility, sporulation, and specialized colonial behavior; four components of bacterial pathogenicity for animals; and pathogenic and symbiotic interactions of bacteria with higher plants. The final chapter explains some of the concepts and the progress being made in the application of population genetics to bacteria. This book may be of interest to microbiologists wishing to catch up on the genetic basis of some of the classical phenomena of bacteriology, and geneticists unfamiliar with some of the things that bacteria can accomplish.

Table of Contents

  • Contributors


    Section I Introductory Chapters: the Diversity of Bacteria and of Bacterial Genetics

    Chapter 1 Bacterial Diversity: the Range of Interesting Things that Bacteria Do

    I. Introduction

    II. Ecological Niches

    III. Towards a Phylogeny of Bacteria

    IV. Reinvention throughout the Phylogenetic Tree

    V. Some Unexpected Attributes of Bacteria

    VI. Conclusion



    Chapter 2 Diversity of Bacterial Genetics

    I. Introduction

    II. The Prokaryotic Genome

    III. Transfer of Chromosomal DNA between Bacteria

    IV. Gene Expression

    V. Gene-, Pathway- and Regulon-Specific Regulatory Mechanisms

    VI. Differences between Prokaryote and Eukaryote Genetics

    VII. Closing Remarks



    Chapter 3 Cloning and Molecular Analysis of Bacterial Genes

    I. Introduction

    II. Cloning Bacterial DNA

    III. Mutagenesis with Cloned DNA

    IV. Biochemical Procedures that Exploit Cloned DNA

    V. Current Limitations and Possibilities


    Section II Specialized Metabolic Capabilities of Bacteria

    Chapter 4 Regulation of Luminescence in Marine Bacteria

    I. Introduction

    II. Organization and Function of lux Genes

    III. Regulation of lux Expression

    IV. Luminescence Variation

    V. Conclusions



    Chapter 5 Photosynthesis in Rhodospirillaceae

    I. Introduction

    II. Structure-Function of the Photosynthetic Apparatus

    III. Protein Components of the Photosynthetic Apparatus

    IV. Photosynthetic Apparatus Genes

    V. In Vitro Mutagenesis Studies

    VI. Genetic Engineering in Reaction Centers


    Chapter 6 The Genetics of Nitrogen Fixation

    I. The Diversity of Nitrogen-Fixing Bacteria

    II. The nif Genes of Klebsiella pneumoniae

    III. The Assembly of Active Nitrogenase

    IV. The Biochemistry and Physiology of Nitrogenase

    V. The Three Nitrogenases of Azotobacter

    VI. nif Genes in Other Organisms

    VII. Rearrangement of nif Genes in Anabaena

    VIII. Regulation of Expression of nif Genes

    IX. Concluding Remarks



    Chapter 7 Antibiotic Biosynthesis in Streptomyces

    I. Introduction to Streptomyces Biology

    II. Antibiotic Production

    III. Molecular Genetics of Antibiotic Production

    IV. Overview, Implications and Prospects


    Chapter 8 Catabolism of Aromatic Hydrocarbons by Pseudomonas

    I. Introduction

    II. Biochemical Strategies for Oxidative Catabolism of Aromatics

    III. Organization and Regulation of Genes for Catabolism of Aromatic Hydrocarbons

    IV. Utility of Determinants of Catabolic Pathways

    V. Laboratory Evolution of Aromatic Catabolic Pathways

    VI. Concluding Remarks



    Chapter 9 Mercury Resistance in Bacteria

    I. Introduction

    II. Bacterial Transformations of Mercury

    III. Mercury Resistance Genes

    IV. The Gram-Negative Structural Genes and Their Products

    V. A Model for Mercury Resistance in Bacteria

    VI. Regulation of Expression of the Mercury Resistance Genes

    VII. Overview and Prospects



    Section III Morphological Differentiation—Flagella Spores and Multicellular Development

    Chapter 10 Differentiation in Caulobacter: Flagellum Development, Mobility and Chemotaxis

    I. Introduction

    II. Developmental Programs and Cell Differentiation

    III. Regulation of Flagellum Biosynthesis

    IV. Control of Chemotaxis and Positioning of Differentiated Structures

    V. Prospects — The Cell Cycle as a Regulator of Temporal and Spatial Patterning



    Chapter 11 Pathways of Developmentally Regulated Gene Expression in Bacillus subtilis

    I. Introduction

    II. Sporulation and Germination

    III. Genes Involved in Sporulation and Germination

    IV. Developmental Genes are Switched on in an Ordered Temporal Sequence

    V. Compartmentalization of Gene Expression

    VI. Dependence Patterns of Developmental Gene Expression: Four Examples

    VII. Pathways of Developmentally Regulated Gene Expression

    VIII. Overview, Implications and Prospects



    Chapter 12 Multicellular Development in Myxobacteria

    I. Introduction

    II. Fruiting Body Development Follows a Program

    III. Operon Fusions Expose a Program of Differential Gene Expression

    IV. Cell Interactions Coordinate the Program of Fruiting Body Development

    V. Mutants of Groups A, B, C and D Differ Genetically

    VI. Expression of ß-Galactosidase from lac Fusion Strains Depends on the Products of the asg, bsg, csg and dsg Genes

    VII. A-Factor and C-Factor Activities can be Found in Cell Extracts

    VIII. The asg, bsg, csg and dsg Loci Can be Isolated

    IX. Overview and Prospects


    Section IV Bacterial Adaptations to Animal Pathogenicity

    Chapter 13 The Molecular Basis of Antigenic Variation in Pathogenic Neisseria

    I. Introduction

    II. Diversity and Virulence

    III. Genetic Mechanisms for Pilus Variation

    IV. Genetic Mechanisms for P.II Variation

    V. Conclusions



    Chapter 14 Adhesins of Pathogenic Escherichia coli

    I. Introduction

    II. Bacterial Adherence to Animal Tissues

    III. Adhesin Genetics

    IV. Evolutionary Perspectives


    Chapter 15 Genetic Studies of Enterotoxin and Other Potential Virulence Factors of Vibrio cholerae

    I. Introduction

    II. Cholera Toxin Genes

    III. Adherence and Colonization

    IV. Other Potential Virulence Factors

    V. Regulation of Virulence Gene Expression

    VI. Perspectives


    Chapter 16 Iron Scavenging in the Pathogenesis of Escherichia coli

    I. Introduction

    II. Enterobacterial Iron Uptake Systems

    III. Molecular Genetics

    IV. Biochemical Genetics

    V. Regulation

    VI. Epilogue


    Section V Bacteria that Interact with Plants as Parasites or Symbionts

    Chapter 17 Pathogenicity of Xanthomonas and Related Bacteria towards Plants

    I. Introduction

    II. Strategies and Techniques for Studying the Genetics of Pathogenicity

    III. Function of Some Pathogenicity Genes

    IV. Concluding Remarks


    Chapter 18 Tumorigenicity of Agrobacterium on Plants

    I. Introduction

    II. Ti and Ri Plasmids

    III. T-DNA

    IV. Genes and Sequences Necessary for T-DNA Transfer

    V. Different Steps in the Process of Tumor Induction

    VI. Prospects for Application


    Chapter 19 The Symbiosis between Rhizobium and Legumes

    I. Introduction

    II. Methods for Identifying Bacterial Genes Involved in Nodulation

    III. Polysaccharide Synthesis is Important for Nodulation

    IV. Analysis of nod Gene Function

    V. Regulation of nod Gene Transcription

    VI. Conclusions


    Section VI Bacterial Population Genetics

    Chapter 20 The Population Genetics of Bacteria

    I. Introduction

    II. Genetic Variation and its Interpretation

    III. Species Boundaries and Evolutionary Relationships

    IV. The Importance of Accessory Elements

    V. Experimental Evolution

    VI. The Planned Release of Novel Organisms


Product details

  • No. of pages: 466
  • Language: English
  • Copyright: © Academic Press 1988
  • Published: December 1, 1988
  • Imprint: Academic Press
  • eBook ISBN: 9781483273556

About the Editors

David A. Hopwood

Keith F. Chater

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