Genetics and Molecular Biology of Entomopathogenic Fungi

Genetics and Molecular Biology of Entomopathogenic Fungi

1st Edition - April 27, 2016

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  • Editors: Brian Lovett, Raymond St. Leger
  • eBook ISBN: 9780444637239
  • Hardcover ISBN: 9780128046944

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Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions, This thematic volume focuses on the advances and the future potential of the rapidly growing field of entomopathogenic fungi. With a focus on the genetics and molecular biology behind the progress, techniques developed to study all aspects of these fungi will be highlighted, and topics will span from systematics of fungi to how a fungus infects an insect and how that insect responds. 

Key Features

  • Critically analyzes future directions for the study of clinical genetics
  • Written and edited by recognized leaders in the field
  • Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics


Molecular geneticists, clinical geneticists, neurologists, neuroscientists, molecular biologists, and biochemists.

Table of Contents

    • Advances in Genetics, Volume 94
    • Dedication
    • Preface
    • Chapter One. Diversity of Entomopathogenic Fungi: Which Groups Conquered the Insect Body?
      • 1. Introduction
      • 2. The Major Groups of Entomopathogenic Fungi and Oomycetes
      • 3. Methods
      • 4. Results
      • 5. Discussion
      • 6. Conclusion
      • Supplementary data
    • Chapter Two. Utilizing Genomics to Study Entomopathogenicity in the Fungal Phylum Entomophthoromycota: A Review of Current Genetic Resources
      • 1. Introduction
      • 2. Genetic Tools Used for Phylogenetic Inference, Evolution, and Epizootiology
      • 3. Host–Pathogen Interactions
      • 4. Genome Characteristics
      • 5. Insights to Be Gained From Entomophthoromycota Genomic Resources
    • Chapter Three. Advances in Genomics of Entomopathogenic Fungi
      • 1. Introduction
      • 2. Evolutionary Relationships of Entomopathogenic Fungi
      • 3. Evolution of Sex in Entomopathogenic Fungi
      • 4. Evolution of Fungal Host Specificity
      • 5. Protein Family Expansions and Contractions
      • 6. Horizontal Gene Transfer
      • 7. Conclusions and Future Perspectives
    • Chapter Four. Insect Pathogenic Fungi as Endophytes
      • 1. Introduction
      • 2. Evolution of Endophytic Insect Pathogenic Fungi
      • 3. Multifunctional Lifestyles
      • 4. Relationship Between Insect Pathogen Genes and Endophytism
      • 5. Application of Endophytic Insect Pathogenic Fungi
      • 6. Secondary Metabolites
    • Chapter Five. Genetically Engineering Entomopathogenic Fungi
      • 1. Introduction
      • 2. Improving Virulence
      • 3. Improving the Efficacy of Mycoinsecticides to Control Vector-Borne Diseases
      • 4. Improve Tolerance to Abiotic Stresses
      • 5. Promoters Used for Genetic Engineering of Entomopathogenic Fungi
      • 6. Methods to Mitigate the Safety Concerns of Genetically Modified Entomopathogenic Fungi
      • 7. Conclusion
    • Chapter Six. Molecular Genetics of Beauveria bassiana Infection of Insects
      • 1. Introduction
      • 2. The Infection Process
      • 3. Techniques for Molecular Manipulation of Beauveria bassiana
      • 4. What Constitutes a Virulence Factor?
      • 5. Genetic Dissection in Beauveria bassiana
      • 6. Conclusions and Future Prospects
    • Chapter Seven. Insect Immunity to Entomopathogenic Fungi
      • 1. Behavioral Avoidance of Pathogens
      • 2. The Impact of Physiological State on Immune Functions in Insects
      • 3. Cuticle as a Barrier to Microbial Infections
      • 4. Overview of Insect Immune Defense Mechanisms
      • 5. Immune Recognition of Fungi
      • 6. Cellular Immune Responses to Fungi
      • 7. Interaction of Fungi with the Phenoloxidase and Coagulation Responses
      • 8. Humoral Immune Responses to Fungi
      • 9. The Evolutionary Genetics of Insect Immunity
      • 10. Fungal Countermeasures to Host Immunity
      • 11. Tolerance versus Resistance
      • 12. Concluding Remarks and Future Perspectives
    • Chapter Eight. Disease Dynamics in Ants: A Critical Review of the Ecological Relevance of Using Generalist Fungi to Study Infections in Insect Societies
      • 1. Introduction
      • 2. Origin and Trends of Using Generalist Fungal Parasites to Study Ant–Fungal Parasite Interactions
      • 3. The Ecological Relevance of Laboratory Experimentation With Beauveria and Metarhizium in Ants
      • 4. Natural Occurrence of Beauveria and Metarhizium in Ants: Opportunistic Parasites?
      • 5. Future Perspectives
      • Supplementary data
    • Chapter Nine. Entomopathogenic Fungi: New Insights into Host–Pathogen Interactions
      • 1. Introduction
      • 2. Pre-adhesion and Community-Level Immunity
      • 3. Adhesion and Pre-penetration Events
      • 4. Penetration of the Integument
      • 5. Post-penetration HPI
      • 6. Fungal Strategies to Evade and/or Tolerate the Host's Immune Response
      • 7. Using Knowledge of HPI in Pest Control Programs
    • Chapter Ten. Molecular Genetics of Secondary Chemistry in Metarhizium Fungi
      • 1. Introduction
      • 2. The Small Molecule Metabolites of Metarhizium
      • 3. Molecular Bases of Secondary Metabolism in the Genus Metarhizium
      • 4. Conclusions
      • Supplementary Data
    • Chapter Eleven. From So Simple a Beginning: The Evolution of Behavioral Manipulation by Fungi
      • 1. Introduction
      • 2. What Is Behavioral Manipulation?
      • 3. Diversity of Fungi Controlling Animal Behavior
      • 4. Tinbergen's Four Questions as They Apply to Behavioral Manipulation of Arthropods by Fungi
      • 5. Mechanisms of Behavioral Manipulation
      • 6. Can Behavioral Manipulation be Evolved In Silico?
      • 7. Conclusion
    • Index

Product details

  • No. of pages: 512
  • Language: English
  • Copyright: © Academic Press 2016
  • Published: April 27, 2016
  • Imprint: Academic Press
  • eBook ISBN: 9780444637239
  • Hardcover ISBN: 9780128046944

About the Serial Volume Editors

Brian Lovett

Dr. Lovett works at the Entomology Department at the University of Maryland.

Affiliations and Expertise

Entomology Department, University of Maryland, USA

Raymond St. Leger

Dr. St. Leger works at the Entomology Department at the University of Maryland.

Affiliations and Expertise

Entomology Department, University of Maryland, USA

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  • Claudia l. Mon May 14 2018

    It s an excellent and

    It s an excellent and very complete and updated book on the subject.