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- Emphasizes the molecular genetics of antibiotic production * Provides the latest information on the organization of genes encoding the biosynthetic pathway * Explores the mechanisms governing their expression and regulation * Examines the role of resistance genes in protecting organisms from their own lethal products
Genetics and Biochemistry of Antibiotic Production brings together the most up-to-date information on the genetic and biochemical mechanisms involved in antibiotic production. A collection of internationally recognized authors provide the latest information on the organization, function and regulation of genes responsible for antibiotic synthesis in a range of bacteria. This unique book groups antibiotics according to their biosynthetic affiliation, providing a background into evolutionary relationships while raising intriguing questions about the raison d'etre of antibiotics in nature.
Global physiological controls; Genetics of antibiotic productio in Streptomyces Coelicolor A3(2), a model streptomycete; Autoregulators; Peptides; Peptidolactones; Bialaphos; Thiopeptides; Beta-lactams; Blycopeptides; Lantibiotics; Microcins; Anthracyclines; Tetracyclines; Macrolides; Avermectins; Polyethers; Ansamycins; Chloramphenicol; Streptomycin and related aminoglycosides; Aminoglycosides and aminocyclitols; Polyoxins and related nucleosides; Agrocins; Isoprenoid antibiotics.
- No. of pages:
- © Butterworth-Heinemann 1994
- 1st November 1994
- eBook ISBN:
Professor, Dalhousie University
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