Genetically Modified Plants - 2nd Edition - ISBN: 9780128185643

Genetically Modified Plants

2nd Edition

Assessing Safety and Managing Risk

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Authors: Roger Hull Graham Head George Tzotzos
Hardcover ISBN: 9780128185643
Imprint: Academic Press
Published Date: 1st August 2020
Page Count: 300
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Genetically Modified Plants, Second Edition, provides an updated roadmap and science-based methodology for assessing the safety of genetic modification technologies, as well as risk assessment approaches from regulators across different agroecosystems. This new edition also includes expanded coverage of technologies used in plant improvement, such as RNA-dependent DNA methylation, reverse breeding, agroinfiltration, and gene-editing technologies such as CRISPR and TALENS. This book is an essential resource for anyone interested in crop improvement, including students and researchers, practitioners in regulatory agencies, and policymakers involved in plant biotechnology risk assessment.

Key Features

  • Provides a roadmap for assessing the safety of genetically modified plants
  • Expands coverage of technologies used in plant improvement, such as RNA-dependent DNA methylation, Reverse Breeding and Agro-infiltration
  • Introduces new chapters addressing the potential applications and associated risks of new gene editing technologies such as CRISPR and TALENS


Practitioners in national regulatory agencies, policy makers involved in biotechnology risk assessment, researchers and students in the fields of plant molecular biology, plant genomes and crop improvement

Table of Contents

1. Setting the context: GM- and gene-editing technologies and perceived biosafety concerns
2. Setting the context: History of Agronomic Systems
3. Setting the context: Conventional approaches to overcome constraints and their limitations
4. Principles of risk assessment
5. Risk assessment and management: human and animal health
6. Risk assessment and management: environment
7. Risk perception and public attitudes to GM
8. Regulatory frameworks
9. Appendices


No. of pages:
© Academic Press 2020
1st August 2020
Academic Press
Hardcover ISBN:

About the Author

Roger Hull

Roger Hull

Roger Hull graduated in Botany from Cambridge University in 1960, and subsequently studied plant virus epidemiology at London University’s Wye College, gaining a PhD in 1964. He lectured on agricultural botany there between 1960 and 1965.

He was seconded to Makerere University in Kampala, Uganda in 1964 where he taught, and learnt tropical agricultural botany and studied the epidemiology of groundnut rosette disease. By watching aphids land on groundnut plants he gained an understanding of the edge effect of spread of virus into the field. In 1965 Roger Hull joined Roy Markham at the ARC Virus Research Unit in Cambridge, UK where he worked on biophysical and biochemical characterization of a range of viruses, especially Alfalfa mosaic virus. This work continued when he moved to the John Innes Institute, Norwich with Roy Markham in 1968. There Dr Hull became a project leader and deputy head of the Virus Research Department. In 1974 he spent a sabbatical year with Bob Shepherd in the University of California, Davis where he worked on the characterization of cauliflower mosaic virus. There he was introduced to the early stages of molecular biology which changed the direction of his research. On returning to the John Innes Institute he applied a molecular biological approach to the study of cauliflower mosaic virus elucidating that it replicated by reverse transcription, the first plant virus being shown to do so. Involvement with the Rockefeller Rice Biotechnology Program reawakened his interest in tropical agricultural problems and he led a large group studying the viruses of the rice tungro disease complex. He also promoted the use of transgenic technology to the control of virus diseases and was in the forefront in discussing biosafety issues associated with this approach. Moving from rice to bananas (plantains) his group was among those who discovered that the genome of banana streak badnavirus was integrated into the host genome and in certain cultivars was activated to give episomal infection – another first for plant viruses. He retired at the statutory age in 1997.

Dr Hull is an Honorary Professor at Peking and Fudan Universities, a Doctoris Honoris Causa at the University of Perpignan, France, and a Fellow of the American Phytopathological Society. He is an Emeritus Fellow at the John Innes Centre where he continued research on banana streak virus for five or more years after retirement. He has published over 225 peer-reviewed papers on plant virology, many reviews and four books including the previous edition of Plant Virology and Comparative Plant Virology.

In retirement Roger Hull became involved in promoting the uptake of transgenic technology by developing countries as one approach to alleviating food insecurity. He is on the International faculty of e-learning diploma course training decision makers, mainly in developing countries, in plant biotechnology regulation. His other interests are gardening, bird watching, travelling and his children and grandchildren.

Affiliations and Expertise

John Innes Center, Norwich, UK

Graham Head

Graham Head is the Global Resistance Management Strategy Lead at Monsanto LLC (now Bayer Crop Science) in St. Louis, MO, USA. Dr Head leads a team with global, cross-crop accountability for insect and weed resistance management strategy development and implementation. He has over 100 peer-reviewed journal articles, has written 9 book chapters and authored 1 book.

Affiliations and Expertise

Monsanto LLC, St. Louis, MO, USA

George Tzotzos

George Tzotzos is the Senior Researcher for Biodiversity Group at the Vale Institute of Technology in Belém, Brazil. Dr. Tzotzos has authored 4 books, 6 book chapters and over 20 peer-reviewed papers.

Affiliations and Expertise

United Nations Industrial Development Organization (UNIDO), Austria

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