Genetic Engineering and Genome Editing for Zinc Biofortification of Rice

Genetic Engineering and Genome Editing for Zinc Biofortification of Rice provides the first single-volume comprehensive resource on genetic engineering approaches, including novel genome editing techniques, to be　carried out in rice, a staple crop for much of the world’s population.

Dietary Zinc deficiency can lead to negative health outcomes, including increased risk of stunting, respiratory diseases, diarrhoea and mortality during childhood, and preterm births in pregnancy. Although providing access to diverse diet is an ideal solution to alleviate zinc deficiency, it may not be a viable solution option in developing countries. Zinc biofortification, a process of increasing zinc concentration in the edible part of food crops, has been proposed as a sustainable approach that can reach people living in remote rural areas, complementing other interventions, such as supplementation and industrial fortification. While Zinc biofortification can be achieved through conventional breeding, genetic engineering, and agronomic practices, this is the first reference to bring all the latest insights and understanding to a comprehensive resource, based on real-world experience and with targeted application.

Providing a complete view of the need for Zinc biofortification in rice, sections in this book discuss state-of-the-art scientific advances, and then goes further, placing them in their proper scientific, regulatory, and socio-economic contexts.

• Compiles the state-of-the-art information to allow fast-track understanding and application of zinc content improvement
• Discusses multiple strategic and methodology approaches
• Includes discussion of the socio-economic implications of improved rice nutritional value

University graduate students (PhD), researchers and educators; Libraries and professionals of universities and various kinds of institutes focused on Agriculture, environmental science, plant science (crop improvement, plant breeding and genetics, plant molecular biology, plant protection, quality improvement)

1. Potential of genetic engineering and genome editing for zinc biofortification in rice
2. Molecular mechanisms of zinc uptake and translocation in rice
3. Zinc biofortification, key enzymes in the phytosiderophores biosynthetic pathway
4. Zinc biofortification, citrate transporter
5. Zinc biofortification, phytosiderophore transporter
6. Zinc biofortification, vacuolar efflux transporter of DMA
7. Zinc biofortification, iron‐regulated transporter
8. Zinc biofortification, iron(II)-nicotianamine transporter
9. Zinc biofortification, cell number regulator
10. Zinc bioavailability, phytate reduction
11. Stages in the development of GM crops for commercialization
12. Genome editing, next generation
13. Current status on the regulation of genome-edited plants
14. Regulatory hurdles facing biofortified genetically modified crops
15. Economic implications of genetically modified and genome edited high Zn-rice