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Genetic Engineering and Genome Editing for Zinc Biofortification of Rice provides the first single-volume comprehensive resource on genetic engineering approaches, including novel genome editing techniques, to be carried out in rice, a staple crop for much of the world’s population.
Dietary Zinc deficiency can lead to negative health outcomes, including increased risk of stunting, respiratory diseases, diarrhoea and mortality during childhood, and preterm births in pregnancy. Although providing access to diverse diet is an ideal solution to alleviate zinc deficiency, it may not be a viable solution option in developing countries. Zinc biofortification, a process of increasing zinc concentration in the edible part of food crops, has been proposed as a sustainable approach that can reach people living in remote rural areas, complementing other interventions, such as supplementation and industrial fortification. While Zinc biofortification can be achieved through conventional breeding, genetic engineering, and agronomic practices, this is the first reference to bring all the latest insights and understanding to a comprehensive resource, based on real-world experience and with targeted application.
Providing a complete view of the need for Zinc biofortification in rice, sections in this book discuss state-of-the-art scientific advances, and then goes further, placing them in their proper scientific, regulatory, and socio-economic contexts.
- Compiles the state-of-the-art information to allow fast-track understanding and application of zinc content improvement
- Discusses multiple strategic and methodology approaches
- Includes discussion of the socio-economic implications of improved rice nutritional value
University graduate students (PhD), researchers and educators; Libraries and professionals of universities and various kinds of institutes focused on Agriculture, environmental science, plant science (crop improvement, plant breeding and genetics, plant molecular biology, plant protection, quality improvement)
1. Potential of genetic engineering and genome editing for zinc biofortification in rice
2. Molecular mechanisms of zinc uptake and translocation in rice
3. Zinc biofortification, key enzymes in the phytosiderophores biosynthetic pathway
4. Zinc biofortification, citrate transporter
5. Zinc biofortification, phytosiderophore transporter
6. Zinc biofortification, vacuolar efflux transporter of DMA
7. Zinc biofortification, iron‐regulated transporter
8. Zinc biofortification, iron(II)-nicotianamine transporter
9. Zinc biofortification, cell number regulator
10. Zinc bioavailability, phytate reduction
11. Stages in the development of GM crops for commercialization
12. Genome editing, next generation
13. Current status on the regulation of genome-edited plants
14. Regulatory hurdles facing biofortified genetically modified crops
15. Economic implications of genetically modified and genome edited high Zn-rice
- No. of pages:
- © Academic Press 2022
- 1st February 2022
- Academic Press
- Paperback ISBN:
PhD in Genetics, Osmania University, Hyderabad, India MSc in Genetics and Plant Breeding, University of Agricultural Sciences, Dharwad, Karnataka, India; BSc (Agriculture), University of Agricultural Sciences, Bangalore, Karnataka, India Professional Experience: Currently Senior Scientist I-Senior Breeder, IRRI, Los Banos, Laguna, Philippines Scientist II- Rice Breeder, IRRI, Los Banos, Laguna, Philippines Scientist I-Rice Breeder, at IRRI, Los Banos, Laguna, Philippines Postdoctoral Fellow - at IRRI, Los Banos, Laguna, Philippines Visiting Research Fellow - at IRRI, Los Banos, Laguna, Philippines Senior Research Fellow (CSIR)- Indian Institute of Rice Research, Hyderabad, India Junior Research Fellow (CSIR)- Indian Institute of Rice Research, Hyderabad, India Senior Research Fellow (ICAR) –Indian Institute of Rice Research, Hyderabad, India Main research topics: Breeding for healthier rice varieties, high beta-carotene, iron and zinc.
Currently Senior Scientist I-Senior Breeder, IRRI, Los Banos, Laguna, Philippines
Dr. Anca Macovei earned a degree in Biology and a Masters Degree in Plant Genetic Engineering at the ‘Babes-Bolyai’ University in Cluj-Napoca (Romania) followed by a PhD Degree in Genetics and Molecular Biology at the University of Pavia (Italy). Post-doc fellowships were at the International Center for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India and International Rice Research Institute (IRRI), Manila, Philippines Currently, an Assistant Professor at the Department of Biology and Biotechnology (Plant Biotechnology Laboratory), University of Pavia (Italy), main research topics are molecular profiling of seed quality, plant DNA Damage Response (DDR).
Assistant Professor, Department of Biology and Biotechnology (Plant Biotechnology Laboratory), University of Pavia, Italy
Dr. Kurniawan Rudi Trijatmiko earned a degree in Agriculture at the Gadjah Mada University in Yogyakarta (Indonesia) in 1994. Master Degree in Biotechnology at the Bogor Agricultural University (Indonesia) in 2000. PhD Degree in Plant Sciences at the Wageningen University (Netherlands) in 2005.Following Post-doc fellowships at the International Rice Research Institute (IRRI), Los Baños, Philippines (2009-2011) and Project Scientist at IRRI (2014-2016). Dr.Trijatmiko is currently working as a Scientist I at the Genetic Transformation Laboratory, IRRI with focus on main research topics: engineering rice for high beta-carotene, iron and zinc.
Scientist I, Genetic Transformation Laboratory, International Rice Research Institute, Los Baños, 4030 Laguna, Philippines
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