Gene Expression

Gene Expression

Protein Synthesis and Control RNA Synthesis and Control Chromatin Structure and Function

1st Edition - January 1, 1978

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  • Editors: Brian F. C. Clark, Hans Klenow, Jesper Zeuthen
  • eBook ISBN: 9781483154060

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Gene Expression provides research papers on selected topics in gene expression, presented at the 11th meeting of the Federation of European Biochemical Societies, held at Copenhagen in August 1977. The book presents research knowledge provided by eminent researchers in the field of biochemistry. Each chapter contains material that is important to other researchers, such as on initiation mechanism of protein synthesis in prokaryotes; translocation mechanism of the ribosome; and analysis of ribosomal translocation by drugs. Mechanisms for the intracellular compartmentation of newly synthesized proteins; RNA synthesis and control; the sub-structure of nucleosome core particles; and future prospects on chromosome structure and function are detailed as well. The text will be of use to researchers and workers in the field of medicine, pharmacology, gene therapy, and biochemistry.

Table of Contents

  • General Introduction to the Proceedings


    Section A. Protein Synthesis and Control


    1. Initiation and Control of Protein Synthesis

    Initiation Mechanism of Protein Synthesis in Prokaryotes

    Eukaryotic Initiation of Protein Synthesis

    Regulation of Eukaryotic Protein Chain Initiation

    Cryptic Initiation Sites in Eukaryotic Virus mRNAs

    Interferon-induced Translational Regulation

    2. Elongation and Control of Protein Synthesis

    The Binding of AAtRNA to Prokaryotic Ribosomes

    Trans-location Mechanism of the Ribosome

    Analysis of Ribosomal Translocation by Drugs

    Regulation of Esoheriohia ooli Elongation Factor. Synthesis In Vivo

    Mechanisms for the Intracellular Compartmentation of Newly Synthesized Proteins

    3. Structure and Function of Components of Protein Synthesis

    Ribosomal Protein-Nucleic Acid Interaction

    Ribosome Structure and Functional Sites

    Section B. RNA Synthesis and Control


    Binding of E. Coli RNA Polymerase to Poly (d(A-s4T)) Studies Using the Filter Retention Assay

    Control of E. Coli rDNA Transcription In Vivo and In Vitro

    RNA Synthesis Termination Factor Rho

    The Role of Rho in Transcription Termination in E. Coli

    Biochemistry of Development of E. Coli Viruses T7 and T1

    Eukaryotic RNA Polymerases

    In Vitro Transcription of the Adenovirus Type 2 Genome

    Section C. Chromatin Structure and Function


    The Sub-Structure of Nucleosome Core Particles

    Studies on Chromatin Structure by Nuclease Digestion

    X-Ray Crystallographic and Enzymatic Analysis of Nucleosome Cores

    Higher Order Structure of Mitotic Chromosomes

    Isolation and Characterization of Eukaryotic DNA Fragments Containing Structural Genes and Adjacent Sequences

    Structure and Transcription of the Free Ribosomal RNA Genes in Tetrahymena

    Suppression of Transcription in Balbiani Ring 2 and the Effect on Chromosome Structure

    The Effect of Heat Shock on Gene Expression in Drosophila Melanogaster

    Chromosome Structure and Function: Future Prospects


Product details

  • No. of pages: 310
  • Language: English
  • Copyright: © Pergamon 1978
  • Published: January 1, 1978
  • Imprint: Pergamon
  • eBook ISBN: 9781483154060

About the Editors

Brian F. C. Clark

Hans Klenow

Jesper Zeuthen

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