Gene Expression - 1st Edition - ISBN: 9780080226248, 9781483154060

Gene Expression

1st Edition

Protein Synthesis and Control RNA Synthesis and Control Chromatin Structure and Function

Editors: Brian F. C. Clark Hans Klenow Jesper Zeuthen
eBook ISBN: 9781483154060
Imprint: Pergamon
Published Date: 1st January 1978
Page Count: 310
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Description

Gene Expression provides research papers on selected topics in gene expression, presented at the 11th meeting of the Federation of European Biochemical Societies, held at Copenhagen in August 1977. The book presents research knowledge provided by eminent researchers in the field of biochemistry. Each chapter contains material that is important to other researchers, such as on initiation mechanism of protein synthesis in prokaryotes; translocation mechanism of the ribosome; and analysis of ribosomal translocation by drugs. Mechanisms for the intracellular compartmentation of newly synthesized proteins; RNA synthesis and control; the sub-structure of nucleosome core particles; and future prospects on chromosome structure and function are detailed as well. The text will be of use to researchers and workers in the field of medicine, pharmacology, gene therapy, and biochemistry.

Table of Contents


General Introduction to the Proceedings

Foreword

Section A. Protein Synthesis and Control

Introduction

1. Initiation and Control of Protein Synthesis

Initiation Mechanism of Protein Synthesis in Prokaryotes

Eukaryotic Initiation of Protein Synthesis

Regulation of Eukaryotic Protein Chain Initiation

Cryptic Initiation Sites in Eukaryotic Virus mRNAs

Interferon-induced Translational Regulation

2. Elongation and Control of Protein Synthesis

The Binding of AAtRNA to Prokaryotic Ribosomes

Trans-location Mechanism of the Ribosome

Analysis of Ribosomal Translocation by Drugs

Regulation of Esoheriohia ooli Elongation Factor. Synthesis In Vivo

Mechanisms for the Intracellular Compartmentation of Newly Synthesized Proteins

3. Structure and Function of Components of Protein Synthesis

Ribosomal Protein-Nucleic Acid Interaction

Ribosome Structure and Functional Sites

Section B. RNA Synthesis and Control

Introduction

Binding of E. Coli RNA Polymerase to Poly (d(A-s4T)) Studies Using the Filter Retention Assay

Control of E. Coli rDNA Transcription In Vivo and In Vitro

RNA Synthesis Termination Factor Rho

The Role of Rho in Transcription Termination in E. Coli

Biochemistry of Development of E. Coli Viruses T7 and T1

Eukaryotic RNA Polymerases

In Vitro Transcription of the Adenovirus Type 2 Genome

Section C. Chromatin Structure and Function

Introduction

The Sub-Structure of Nucleosome Core Particles

Studies on Chromatin Structure by Nuclease Digestion

X-Ray Crystallographic and Enzymatic Analysis of Nucleosome Cores

Higher Order Structure of Mitotic Chromosomes

Isolation and Characterization of Eukaryotic DNA Fragments Containing Structural Genes and Adjacent Sequences

Structure and Transcription of the Free Ribosomal RNA Genes in Tetrahymena

Suppression of Transcription in Balbiani Ring 2 and the Effect on Chromosome Structure

The Effect of Heat Shock on Gene Expression in Drosophila Melanogaster

Chromosome Structure and Function: Future Prospects

Index

Details

No. of pages:
310
Language:
English
Copyright:
© Pergamon 1978
Published:
Imprint:
Pergamon
eBook ISBN:
9781483154060

About the Editor

Brian F. C. Clark

Hans Klenow

Jesper Zeuthen