The new third edition of Gene Activity in Early Development reflects the ten years of technological progress since the last edition. Providing a unique blend of classical and molecular knowledge, it discusses all major embryonic systems from both a comparative and mechanistic point of view. In deriving overall interpretations of developmental phenomena, it brings into play all the disparate forms of evidence, including genetic, molecular, and cytological.**This book is written for any serious student or scholar entering the field, whether his or her background is in genetics, molecular biology, or embryology.
(1) This is a textbook for adoption in undergraduate and graduate level courses on developmental biology. (2) As a professional monograph, it will be of interest to the whole range of cell and molecular biologists and geneticists.
From Genome to Embryo: The Regulation of Gene Activity in Early Development. The Nature and Function of Maternal Transcripts. Transcription in the Embryo and Transfer of Control to the Zygotic Genomes. Differential Gene Function in the Embryo. Gene Activity during Oogenesis. Cytoplasmic Localization. Appendix I: Sequence Complexity and the Quantitative Analysis of Renaturation and Hybridization of Experiments Carried Out in Solution. Appendix II. Measurement of Transcript Prevalence by Single-Stranded Probe Excess Titration. Appendix III. Measurement of Rates of Synthesis or Entry into the Cytoplasm, and of Transcript Turnover Rate, from the Kinetics of Incorporation of Labeled Precursors. References. Index.
- © Academic Press 1986
- 25th September 1986
- Academic Press
- eBook ISBN:
@qu:...providing a strongly comparative point of view and generating broad and well-balanced interpretations of large bodies of connected facts. The result is an excellent book... @source:--SCIENCE @qu:It is a meticulously prepared heavyweight review, clearly written but with the density of citation and numerical detail that are the stuff of reference works....an invaluable insurance against having to read more than a fraction of the 1,800 or so references cited. @source:--NATURE @qu:...all who read thebook, undergraduate and senior scientist alike, will find themselves well served by this unique and particularly insightful view of development. @source:--ENGINEERING & SCIENCE