Microbial Toxins, Volume VI: Fungal Toxins covers information on the evaluation of the chemical, biological, and biomedical aspects of the fungal toxins. The book discusses the historical structure chemistry, production, analysis, detoxification, biosynthesis, pharmacology, toxicology, and molecular biochemistry of aflatoxins and related compounds. The text also describes the isolation, analysis, production, chemistry, biological effects, and biogenesis of the ochratoxins, as well as the bioproduction, biosynthesis, and chemical properties of misclellaneous Aspergillus toxins. Various species of storage fungi, including yellowed rice toxins, luteoskyrin and related compounds, chlorine-containing compounds, citrinin, and citreoviridin are also considered. The book further tackles the physical and chemical properties and the biological activity of the rubratoxins; the biosynthesis and biochemical effects of patulin, penicillic acid, and other carcinogenic lactones; as well as the structure, production, biosynthesis, and biological effects of cyclopiazonic acid and related toxins. The text also encompasses bioproduction, properties, chemical structure, and biological activity of miscellaneous Penicillium toxins. Microbiologists, biochemists, epidemiologists, pharmacologists, toxicologists, medical students and people involved in other related fields will find the book useful.
List of Contributors Preface Contents of Other Volumes Introductory Remarks Section A Aspergillus Toxins1. Aflatoxin and Related Compounds I. Introduction (Historical Structure Chemistry) II. Toxin-Producing Fungi III. Toxin-Affected Commodities IV. Production V. Analysis VI. Detoxification VII. Safety Procedures VIII. Biosynthesis IX. Pharmacology and Toxicology X. Molecular Biochemistry XI. Sterigmatocystin XII. Summary References 2. Ochratoxin and Other Dihydroisocoumarins I. Introduction II. Isolation, Analysis, and Production of the Ochratoxins III. Chemistry of the Ochratoxins IV. Biological Effects of Ochratoxin V. Biogenesis of the Ochratoxins and Their Relationship to Other Fungal Dihydroisocoumarins References 3. Miscellaneous Aspergillus Toxins I. Introduction II. Aspergillic Acid and Related Compounds III. Kojic Acid IV. β-Nitropropanoic Acid V. Endotoxins of Aspergillus fumigatus and Aspergillus flavus VI. Helvolic Acid VII. Oxalic Acid VIII. Tremorgenic Toxin from Aspergillus flavus IX. Fumagillin X. Fumigallin and Other Toluquinones References General References Fumagillin
Section B Penicillium Toxins4. Yellowed Rice Toxins Luteoskyrin and Related Compounds, Chlorine-Containing Compounds, and Citrinin Citreoviridin 5. The Rubratoxins, Toxic Metabolites of Penicillium rubrum Stoll I. Introduction II. Penicillium rubrum Stoll III. Growth and Toxin Production IV. The Rubratoxins, Anhydrides, and Lactols V. Chemical and Physical Properties VI. Relationship to Byssochlamic Acid VII. Biological Acti
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- © Academic Press 1971
- 28th January 1971
- Academic Press
- eBook ISBN: