Fundamentals of Biochemical Pharmacology

Fundamentals of Biochemical Pharmacology

1st Edition - January 1, 1971

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  • Editor: Z. M. Bacq
  • eBook ISBN: 9781483157597

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Fundamentals of Biochemical Pharmacology is a basic introduction to the fundamental aspects of pharmacology. It explains the molecular aspects of drugs, as well as the different biochemical systems and cellular strategies that they cause. The book is divided into two sections, the first of which covers physiochemical methods, histological methods, and physiological methods. The second section covers biochemical lesions; functions of subcellular structures; transfer of ions and molecules across cellular membrane; pharmacokinetics; drug receptor interactions; effects of drugs on structure; biosynthesis; catabolism; and biotransformation of drugs. The book is a good reference for pharmacology students who are learning about the the basic underlying concepts of biochemical pharmacology. It will also appeal to researchers with a background in chemistry, biochemistry, biology, microbiology, botany, or zoology.

Table of Contents

  • Preface

    List of Authors

    Section A: Outlines of Methods

    Physicochemical Methods

    1 Introduction to Optical Methods

    2. Electronic and Nuclear Magnetic Resonances

    3 Mass Spectrometry

    4 Isotopic Methods and Activation Analysis

    5 Isolation and Purification Procedures

    6 Immunochemistry and Radioimmunochemistry

    7. Introduction to Enzyme Kinetics

    8 Centrifugation of Subcellular Components

    Histological Methods

    9 Electron Microscopy

    10 Histoautoradiography

    11 Biochemical and Pharmacological Aspects of Histochemistry

    Physiological Methods

    12 Animals and Isolated Organs

    13 Electrophysiological Methods

    14 Behavioral Techniques

    Section B: Biochemical Pharmacology

    1 The Concept of the Biochemical Lesion

    2 Functions of Subcellular Structures

    2.1. Bacterial Walls and Membranes

    2.2. Mitochondria

    2.3. Drugs and Lysosomes

    3 Transfer of Ions and Molecules across Cellular Membranes

    4 Pharmacokinetics

    5 Synaptic Vesicles, Specific Granules, Autopharmacology

    5.1. Cholinergic Transmissions

    5.2. Adrenergic Transmission

    5.3. Indolealkylamines

    5.4. Histamine

    5.5. Prostaglandins

    5.6. Polypeptides

    6 Drug-Receptor Interactions

    7 Chelating Agents

    8 Effects of Drugs on Structure, Biosynthesis and Catabolism of Nucleic Acids, Proteins, Carbohydrates and Lipids

    8.1. Nucleic Acids and Proteins

    8.2. Carbohydrates

    8.3. Drugs Acting on Blood Lipids

    9 Biotransformation of Drugs

    10 Pharmacogenetics

    11 Comparative Pharmacology


Product details

  • No. of pages: 674
  • Language: English
  • Copyright: © Pergamon 1971
  • Published: January 1, 1971
  • Imprint: Pergamon
  • eBook ISBN: 9781483157597

About the Editor

Z. M. Bacq

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