Functionalized Cardiovascular Stents describes the fundamentals of cardiovascular stents, the technologies that functionalize their surfaces, and the market status of these important implants. As cardiovascular disease is a major cause of mortality in the western world, with about half of these deaths caused by coronary artery disease, this book focuses on several treatments, including the deployment of an arterial stent to keep the vessel open.
- Provides a specific focus on cardiovascular stents
- Includes a range of topics covering the fundamentals, surface modification and biofunctionalization
- Provides essential knowledge for researchers on advances in the field
Researchers in the medical device and biomaterials industry
1. Overview of cardiovascular stent designs
2. Fundamentals of bare metal stents
3. Development of drug eluting stents (DES)
4. Polymer-free drug-eluting stents
5. Fundamentals of biodegradable and bioabsorbable stents
6. Physical and mechanical surface modification of cardiovascular stents
7. Surface passivation (chemical vapour deposition) of cardiovascular stents
8. Polymer coatings for biocompatibility and reduced non-specific adsorption
9. Stability of stent coatings
10. Simple one-step immobilisation of bioactive agents without use of chemicals on plasma activated low thrombogenic stents coatings
11. Chemistry of targeted immobilisation of biomediators
12. In vitro coating of cardiovascular stents with cells (EPCs)
13. Nitric oxide donor delivery
14. Immobilisation of peptides on cardiovascular stents
15. Immobilisation of antibodies on cardiovascular stents
16. Bioresorbable metallic stents
- No. of pages:
- © Woodhead Publishing 2018
- 1st October 2017
- Woodhead Publishing
- Hardcover ISBN:
Dr. Gerard Wall obtained his primary degree in Microbiology from the National University of Ireland, Galway, followed by a PhD in Molecular Immunology from the University of Aberdeen, Scotland. After a period spent engineering antibodies at the University of Zurich in Switzerland, he established his own research group in protein engineering, with emphasis on recombinant antibody fragments and their applications, at the University of Limerick, Ireland. He returned to NUI Galway in 2008. He has published widely on recombinant protein expression and engineering, and has particular interests in the fields of antibody engineering, drug delivery and materials functionalisation.
National University of Ireland, Galway, Ireland
Prof. Dr. Halina Podbielska received her PhD, B.Sc. and Engineering Degree in Applied Physics/Optics from the Faculty of Fundamental Problems of Technology of Wroclaw University of Technology (WrUT), Poland and her M.D. degree from the Faculty of Medicine of the Medical University of Wrocław. She received her Habilitation degree in Applied Physics and became Professor of Bio-Optics and Head of the Bio-Optics Group at WrUT. In 2002 she received the scientific title of full Professor of Technical Sciences awarded by the President of Poland and since then she is a full Professor (Ordinarius) at the Faculty of Fundamental Problems of Technology. Her professional experiences include biomedical engineering with emphasis on biomedical optics, sol-gel biomaterials, nanomaterials and their applications, as well physical medicine. She is an author or co-author of over 330 publications. She holds 10 registered patents. Prof. Podbielska was visiting scientist in several scientific institutions worldwide: as an A. v. Humboldt fellow at the University of Frankfurt/Main, University of Muenster, Charite Medizin University of Berlin, Germany, and at the Weizmann Institute of Science, Israel. She was a visiting professor at the Institute of Optics of Technical University in Berlin. She was also visiting professor at the Charite Medicine University in Berlin.
Institute of Biomedical Engineering and Instrumentation, Faculty of Fundamental problems of Technology, Wroclaw University of Technology, Wroclaw, Poland
Dr. Magdalena Wawrzyńska is an interventional cardiologist and internal medicine specialist, a member of European Society of Cardiology and the European Association of Percutaneous Interventions. She obtained her M.D. degree, followed by PhD in Internal Diseases at Wrocław Medical University, Poland and is currently an academic teacher at Wrocław Medical University. Her research focus is experimental cardiology, and diagnosis and advanced treatment of coronary artery diseases. She has been awarded a silver medal at the International Exhibition of Innovation, Entrepreneurship and New Technologies, Eureka Brussels in 2006. Dr Wawrzyńska is the owner of several patent applications in the field of innovative solutions for cardiology.
Wroclaw Medical University, Wroclaw, Poland