Frontiers of Life, Four-Volume Set

1st Edition


  • David Baltimore
  • Renato Dulbecco
  • François Jacob
  • Rita Levi-Montalcini
  • Description

    Frontiers of Life addresses fields of biology in terms of their frontiers--that is, the areas that will demand the most work in this new century. Because of their standing, the editors have been able to unite the most prestigious and well-informed authorities to place recent scientific advances into the context of their effects on daily human experiences and expectations. They ask, "What frontiers of the biological sciences will constitute the challenges of the next century?" Their first answer is an understanding of the processes and mechanisms that led to the origin of life. They take this answer as the starting point of the first section of the Encyclopedia. They thus proceed throughout the four volumes. Separating this Encyclopedia form others is its multidisciplinary approach to the "frontiers" theme. While other encyclopedias strive to describe the past and present states of many subjects, Frontiers of Life offers the insights of world-class scientists into their subjects' growth areas.

    Key Features

    @introbul:Key Features @bul:* Includes Advisory Board with each member a Nobel Laureate * Written by contributors playing leading roles in their fields of expertise * Contains almost 3,000 full color tables and figures, illustrating the 205 articles; color running heads and subtitles within each article make reading easy * Presents biology as an organizing force of life in every article, from the cellular level to the interpersonal


    Major college and university library systems of the world; individuals, corporations, laboratories, and groups interested in the effects of biology on their particular subjects.

    Table of Contents

    Volume 1: THE ORIGINS OF LIFE Part One: ORIGIN AND EVOLUTION OF LIFE Cosmology The Physical and Chemical Basis of Life The Origin of Life Selection and Evolution The Molecules of Inheritance: DNA and RNA Human Origin and Evolution The Organisms Construction Part Two: THE GENETIC CODE Organization of Language and Genetical Information Mechanisms of Genetical Expression Programs of Genetic Expression Genes and Evolution Manipulations and Genetic Errors Volume 2: CELLS AND ORGANISMS Part One: CELLS AND CELL COMMUNITIES The Cell Construction Communication Among Cells Normal and Altered Cell Homeostasis Formation of Organs and Tissues Part Two: THE IMMUNOLOGICAL SYSTEMS Conceptual and Experimental Milestones in Immunology Lymphocyte Development Structure and Function of Antigen Receptors The Generation of Diversity The Cell Biology of Antigen Presentation Signal Transduction and Cell Fate Decision in the Immune System Lymphocyte Selection by Antigen Molecular Circuits of Leukocytic Recruiting Regulation Antigen Presentation In Vivo Cell to Cell Interactions in the Immune System Immunological Memory Cytokine, Chemokine and Relations Between How Parasites Subvert the Immune Surveillance Computer Modelling in Immunology Transgenic and Knock-out Mice as Models of Immune Deficiency Immunology to the Bedside-immunotechnology Vaccination Ho


    No. of pages:
    © 2002
    Academic Press
    Print ISBN:
    Electronic ISBN:

    About the authors

    David Baltimore

    Microbiologist, educator. Gairdner Foundation Annual Award, 1975; US Steel Award in Molecular Biology, 1974. Nobel Prize for Medicine, 1975.

    Renato Dulbecco

    Dr. Renato Dulbecco is President Emeritus and Distinguished Resident Professor at the Salk Institute for Biological Studies in La Jolla, California. Known for his pioneering work in cancer-causing viruses, Dulbecco was awarded the Nobel Prize in medicine/physiology in 1975. At the beginning of his career, Dulbecco devoted his work to the study of virology. During his early research, he developed what continues to be the most widely used technique for growing and maintaining cells in culture and for measuring the activity of animal viruses, such as poliovirus. Subsequently, Dulbecco, working with cancer-producing viruses, was able to show how genes of the virus interact with those of the host cell in tissue culture, which was a fundamental discovery in understanding the uncontrolled proliferation of cells in the cancer process. Dulbecco was born and educated in Italy, and he received his doctorate of medicine from the University Turin in 1936. He joined the Salk Institute as one of the original group of Fellows in 1963 and was associated with the Institute until 1972. From 1972 through 1977, Dulbecco was Deputy Director of the Imperial Cancer Research Laboratory in London. Since rejoining the Salk Institute in 1977, he has held the position of Distinguished Research Professor and Senior Clayton Foundation Investigator. In 1988 he was named President of the Salk Institute. Dulbecco's more recent research has involved the study of the origin of breast cancer. He has studied the various cell types that comprise breast tissue, a necessary first step in the process of understanding how some cells undergo transformation and become malignant. Dulbecco has used monoclonal antibody techniques to study breast cancer in laboratory animals and in humans, with the objective of developing new and reliable means of classifying cells in the breast, and identifying those that may be susceptible to carcinogenic agents. Some of the antibodies he produced have been studied for clinical

    François Jacob

    Professor of genetics, member of the Academie des Sciences, 1977, foreign member of the Royal Danish Academy of Sciences and Letters, 1962, American Academy of Arts and Sciences, 1964, Royal Society, London, 1973. Prix Charles Léopold Mayer, Academie des Sciences, 1962. Nobel Prize for Medicine, 1965.

    Rita Levi-Montalcini

    Director of the Institute of Cell Biology of the Italian National Council of Research, 1969-1978. Nobel Prize for Medicine, 1986.


    "a magnificent four-volume encyclopedia of the life sciences...This set is specifically written for the professional scientist, the university student, and the serious layperson, and editor in chief Andrea Turchi of Treccani has done a masterful job in producing this elegant set for such a learned audience. This set reminds this reviewer of olden times, when each topic of an encyclopedia was assigned to a recognized leader in a field who produced an article of the highest quality, a far cry from the usual CD-ROM encyclopedia of today, which is typically just a compilation of facts by unknown authors... Each article is well illustrated with photographs, sketches, and graphs, and ends with a comprehensive bibliography. An extensive subject index can be found at the end of volume 4. This reviewer enthusiastically recommends this encyclopedia for any life science academic library as well as public libraries serving a scientific clientele." —AMERICAN REFERENCE BOOKS ANNUAL "A remarkable, eccentric, advanced treatise in four large quarto volumes, this set, which the publisher rightly does not call an encyclopedia, covers nine specific areas of contemporary biology... Each section contains about 20 articles, each 15 to 20 pages long, all by major authorities, with excellent and copious color illustrations, and usually 20-100 references, almost all earlier than 1997...The distinctive excellence of this work is found in the extraordinary high quality, readability, and wide-ranging sophistication of the individual articles, which despite the time lag in publication, will motivate well-prepared students to a wider exploration of fascinating subjects... Recommended enthusiastically to graduate or upper-division undergraduate collections." —CHOICE