Frontiers of Bioorganic Chemistry and Molecular Biology

Frontiers of Bioorganic Chemistry and Molecular Biology

Proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, Moscow and Tashkent, USSR, 25 September - 2 October 1978

1st Edition - January 1, 1980

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  • Editor: S. N. Ananchenko
  • eBook ISBN: 9781483278834

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Frontiers of Bioorganic Chemistry and Molecular Biology covers the proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, held in Moscow and Tashkent, USSR on September 25-October 2, 1978. This symposium is devoted to a discussion of the physico-chemical basis of life processes. This book contains 56 chapters, and reflects the results in the study of peptides and proteins, nucleic acids, polysaccharides, and other biopolymers. Other chapters deal with the study of low molecular regulators, including steroids, alkaloids, and antibiotics. This book also includes discussion of the achievements in the study of genetic structures and of cellular protein synthesizing systems of the molecular basis of enzymic catalysis and of bioenergetic processes. This book will be of value to biochemists and molecular biologists.

Table of Contents

  • Introductory Speech

    Indications of a Common Reaction Mechanism of Enzymes Catalyzing the Hydrolysis of Pyrophosphate Bonds

    Highlights in the Study of Enzymic Amino Group Transfer: Metabolic Role, Structure and Catalytic Mechanism of Transaminases

    The Role of Secondary Specificity in Catalysis by Proteolytic Enzymes

    Enzyme Having Covalently Bound Flavins

    Structure and Evolution of Glutamate Dehydrogenases

    Structural and Functional Properties of Cytochrome C Oxidase

    Glycosyl Transferases in Oligosaccharide Biosynthesis and their Use in Structure-Function Analysis of Glycoproteins

    Enzymes for Splitting and Synthesizing the Glycosidic Linkages in Carbohydrate Determinants of Glycoproteins

    A Valinomycin Analogue Containing Only Naturally-Occurring Amino Acids

    Toxic Components from Buthus eupeus and Lucosa singoriensis Venoms

    Physiological Significance of the Constituent Polypetide Chains of Ricin D

    Recognition of Peptide Hormones and Kinins: Molecular Aspects of the Problem

    Synthesis and Structure-Functional Studies on Heme Peptide Models of Natural Oxygen-Binding Hemoproteins

    Proteins of the Cottonseed

    Insulin-Dependent Cytoplasmic Regulator. Separation, Identification and Investigation of Insulin-Like Action

    Progress in the Chemical Synthesis of Proinsulin

    Mitochondrial Membrane-Bound Steroid Hydroxylating Systems: Structure and Functions

    Analysis of Local Environment of Histidine Residues in Proteins by Hydrogen-Tritium Exchange Reaction

    The Conformations Observed in the N Terminal A Chain Residues of Insulin

    Globular Proteins and their Associations

    Complementation of Protein Crystal Structures by NMR Studies in Solution

    Studies of Acid Protease Structures by Molecular Replacement Method

    Drug Metabolism and the Function of Cytochrome P-450

    Changes in Rat Liver Glycolytic Reactions During Fluoroacetate Poisoning

    Chemistry and Biochemistry of Thuringiensin, A Natural Analogue of ATP

    Problems of Studies of Specific Cell Autoregulators (on the Example of Substances Produced by Some Actinomycetes)

    Biological Implications of Recent Discoveries in the Marine Sterol Field

    Problems of Regulation, Synthesis and Metabolism of Natural Compounds

    Some New Results in the Total Synthesis of Estrogens

    Synthetic Approaches to 14-Hydroxysteroids

    New Phytoecdysones

    The Problem of Division of Biological Functions of Endogenous Substances

    Extant Flora with Respect to its Chemistry

    Hormone-Receptor Interactions: A Study of the Molecular Mechanism of Receptor Stimulation in Isolated Fat Cells by the Partial Agonist Corticotropin-(5-24)-Icosapeptide

    Messenger Ribonucleoproteins (Informosomes)

    Selection of mRNA Initiation Sites for Protein Synthesis in Prokaryotes

    The Ribosomal Peptidyl Transferase Center. Possible Bases for the Common Action of Peptide Bond Formation Inhibitors of Bacterial and Eukaryotic Ribosomes

    Aminoacyl-tRNA Synthetases: Approaches to the Structure and Function of the Active Centers

    Diversity of Sugar Pucker in the Nucleic Acids

    Three Levels of Chromatin Structure

    Biosynthesis and Properties of Normal and Mutant E. coli RNA Polymerase

    Isolation, Cloning and Studies on the Structural Organization of Eukaryotic Genes

    Primary Organization and Functioning of the Nucleosome Core Particle of Chromatin

    Polyalkylating RNA Complementary to Selected DNA as a Tool for Gene-Directed Mutagenesis

    Effective Solid Phase Method for the Synthesis of Oligodeoxyribonucleotides

    E.ooli RNA-Polymerase Interactions with the Substrates and Template. The Primary Structures of the Phage 434 Promoters

    The Use of Ultraviolet-Induced Polynucleotide-Protein Crosslinks in Studies of Nucleoprotein Structure

    Structural Studies of the Elongation Factor G from Escheriohia coli

    The Cycling of Ca2+ Across the Inner Mitochondrial Membrane

    Sources of Energy for Membrane Transport in Yeasts

    Lateral Molecular Motions in Membranes

    Appearance of Photoinduced Potential on Photoreceptor Membrane

    The Study of Ionophoric Effect of Some New Derivatives of Cyclic Polyethers on Artificial and Biological Membranes

    Heavy Water Effects on Excitable Membranes

    Mechanisms of Cell Adhesion to Cellular and Non-Cellular Surfaces

    Bioelectrocatalysis as a New Phenomenon

Product details

  • No. of pages: 484
  • Language: English
  • Copyright: © Pergamon 1980
  • Published: January 1, 1980
  • Imprint: Pergamon
  • eBook ISBN: 9781483278834

About the Editor

S. N. Ananchenko

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