COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off our Print & eBook bundle option. Terms & conditions.
From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors - 1st Edition - ISBN: 9780128201879, 9780128201886

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88

1st Edition

0.0 star rating Write a review
Serial Volume Editors: Christopher Langmead
Hardcover ISBN: 9780128201879
eBook ISBN: 9780128201886
Imprint: Academic Press
Published Date: 8th May 2020
Page Count: 328
Sales tax will be calculated at check-out Price includes VAT/GST
358.14
177.00
183.00
256.00
217.60
Unavailable
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

    1. The computational modeling of allosteric modulation of metabotropic glutamate receptors
    2. Laura Pérez-Benito, Claudia Llinas del Torrent, Leonardo Pardo and Gary Tresadern

    3. Structure-based discovery and development of metabotropic glutamate receptor 5 negative allosteric modulators
    4. Kirstie A. Bennett, John A. Christopher and Benjamin G. Tehan

    5. The function and allosteric control of the human sweet taste receptor
    6. Guy Servant, Terry Kenakin, Lan Zhang, Mark Williams and Nicole Servant

    7. The different aspects of the GABAB receptor allosteric modulation
    8. Julie Kniazeff

    9. RAMPs as allosteric modulators of the calcitonin and calcitonin-like class B G protein-coupled receptors
    10. Augen A. Pioszak and Debbie L. Hay

    11. Strategies and considerations of G-protein-coupled receptor photopharmacology
    12. Alice E. Berizzi and Cyril Goudet

    13. Discovery and pharmacology of the covalent GLP-1 receptor (GLP-1R) allosteric modulator BETP. A novel tool to probe GLP-1R pharmacology
    14. Francis S. Willard, Joseph D. Ho and Kyle W. Sloop

    15. Allosteric modulation of metabotropic glutamate receptors in alcohol use disorder: Insights from preclinical investigations
    16. Kari A. Johnson and David M. Lovinger

    17. Allosteric modulation of muscarinic receptors in alcohol and substance use disorders
    18. Leigh C. Walker and Andrew J. Lawrence

    19. M1 muscarinic acetylcholine receptors: A therapeutic strategy for symptomatic and disease-modifying effects in Alzheimer's disease?

Miriam Scarpa, Sarah Hesse and Sophie J. Bradley


Description

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.

Key Features

  • Includes the authority and expertise of leading contributors in pharmacology
  • Presents the latest release in the Advances in Pharmacology series

Readership

Investigators in neuroscience, pharmacology, neurology, psychiatry, medicine


Details

No. of pages:
328
Language:
English
Copyright:
© Academic Press 2020
Published:
8th May 2020
Imprint:
Academic Press
Hardcover ISBN:
9780128201879
eBook ISBN:
9780128201886

Ratings and Reviews


About the Serial Volume Editors

Christopher Langmead

Christopher Langmead is at Monash University, Vic, Australia

Affiliations and Expertise

Monash University, Vic, Australia