From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors - 1st Edition - ISBN: 9780128201879

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88

1st Edition

Serial Volume Editors: Christopher Langmead
Hardcover ISBN: 9780128201879
Imprint: Academic Press
Published Date: 1st June 2020
Page Count: 312
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Table of Contents

1. Targeting muscarinic M1 receptor in neurodegenration
Sophie Bradley
2. Photo‐switchable allosteric ligands
Cyril Goudet
3. Computational approaches for the design of mGlu receptor allosteric modulators
Gary Tresadern
4. Allosteric modulation of GLP‐1 receptor in metabolic disorders
Francis Willard
5. Group II mGluR roles in the nervous system and their roles in addiction
David Lovinger
6. RAMPs as allosteric modulators of Class B GPCRs
Augen A. Pioszak
7. Structure‐based discovery and development of mGlu5 NAMs
Kirstie Bennett
8. Allosteric modulation of taste receptors
Guy Servant
9. Structure‐based identification of adenosine A1 receptor allosteric modulators
Lauren Therese May
10. Allosteric modulation of muscarinic receptors in addiction
Andrew J. Lawrence
11. Mechanisms of allosteric modulation of GABAB receptors
Julie Kniazeff


Description

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.

Key Features

  • Includes the authority and expertise of leading contributors in pharmacology
  • Presents the latest release in the Advances in Pharmacology series

Readership

Investigators in neuroscience, pharmacology, neurology, psychiatry, medicine


Details

No. of pages:
312
Language:
English
Copyright:
© Academic Press 2020
Published:
1st June 2020
Imprint:
Academic Press
Hardcover ISBN:
9780128201879

Ratings and Reviews


About the Serial Volume Editors

Christopher Langmead Serial Volume Editor

Christopher Langmead is at Monash University, Vic, Australia

Affiliations and Expertise

Monash University, Vic, Australia