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From Molecules to Networks - 1st Edition - ISBN: 9780121486600, 9780080491356

From Molecules to Networks

1st Edition

An Introduction to Cellular and Molecular Neuroscience

Editors: John Byrne Ruth Heidelberger M. Waxham James L. Roberts
eBook ISBN: 9780080491356
Hardcover ISBN: 9780121486600
Imprint: Academic Press
Published Date: 10th November 2003
Page Count: 608
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An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. This book provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells that is needed by advanced undergraduates and graduate students, as well as researchers in need of a thorough reference.

Key Features

  • Highly referenced for readers to pursue topics of interest in greater detail
    * Unique coverage of the application of mathematical modeling and simulation approaches not found in other textbooks
    * Richly illustrated, four color presentation throughout
    * Includes CD-ROM of all of the illustrations


Researchers in neuroscience and neurology as well as graduate students in neuroscience and medical students.

Table of Contents

Cellular Components of Nervous Tissue
Subcellular Organization of the Nervous System: Organelles and their Functions
Brain Energy Metabolism
Electronic Properties of Axons and Dendrites
Membrane Potential and Action Potential
Molecular Properties of Ion Channels
Dynamical Properties of Excitable Membranes
Release of Neurotransmitters
Classical Neurotransmitters
Peptides, Growth Factors, Gasses and Other Neurotransmitters
Neurotransmitter Receptors
Intracellular Signaling
Regulation of Neuronal Gene Expression and Protein Synthesis
Mathematical Modeling and Analysis of Intracellular Signaling Pathways
Cell-Cell Communication: An Overview Emphasizing Gap Junctions
Postsynaptic Potentials and Synaptic Integration
Information Processing in Complex Dendrites
Learning and Memory: Basic Mechanisms


No. of pages:
© Academic Press 2003
10th November 2003
Academic Press
eBook ISBN:
Hardcover ISBN:

About the Editors

John Byrne

John Byrne

The June and Virgil Waggoner Professor and Chair, Department of Neurobiology and Anatomy, University of Texas Medical School at Houston. Dr. Byrne is an internationally acclaimed Neuroscientist. He received his PhD under the direction of Noble Prize winner, Eric Kandel. Dr. Byrne is a prolific author and Editor-in-Chief of Learning and Memory (CSHP).

Affiliations and Expertise

University of Texas Medical School, Houston, TX, USA

Ruth Heidelberger

Professor, Department of Neurobiology and Anatomy, University of Texas Medical School at Houston. Dr. Heidelberger is an accomplished cellular neurophysiologist specializing in mechanisms of neurotransmitter release. She received her doctoral training under the guidance of Gary Matthews and her postdoctoral training under the direction of Nobel Laureate Erwin Neher. Dr. Heidelberger is a former president and executive board member of the Biophysical Society's Subgroup on Exocytosis and Endocytosis and serves on the editorial board of the Journal of Neurophysiology. She has directed and taught graduate-level courses in cellular neurophysiology and membrane biophysics for more than a decade.

Affiliations and Expertise

The University of Texas Medical School at Houston, Houston, TX, USA

M. Waxham

The William Wheless III Professor, Department of Neurobiology and Anatomy, University of Texas Medical School at Houston. Dr. Waxham’s multi-disciplinary laboratory focuses on the molecular and cellular mechanisms of synaptic function and plasticity. He has developed and directed graduate-level courses in cellular and molecular neurobiology for more than two decades.

Affiliations and Expertise

The University of Texas Medical School at Houston, Houston, TX, USA

James L. Roberts

Affiliations and Expertise

Trinity University, San Antonio, TX, USA


"From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience, represents a wonderfully new and highly valuable addition to the books currently available for students and practicing scientists. The book, in its unique and creative treatment of quantitative aspects of neurobiology, fills a much-needed gap."
--Eric R. Kandel, University Professor of Physiology and Psychiatry at the Center for Neurobiology and Behavior of the Columbia University College of Physicians and Surgeons

"The Byrne-Roberts volume is an immensely valuable contribution to those of us who teach molecular-cellular neuroscience. It combines rigor in conveying the most up-to-date advances in the field along with simplicity and lucidity of presentation. The illustrations are particularly well done and immensely useful in clarifying complex processes for students."
--Solomon H. Snyder, Professor and Director, Department of Neuroscience, Johns Hopkins University, Johns Hopkins University School of Medicine

"This elegant, beautifully illustrated and up to date book addresses the main themes of neuroscience at a robust and thorough level. A must for anyone wishing a well referenced no nonsense introduction to this important field of contemporary science."
--Rodolfo Llinas, Chairman and Thomas & Suzanne Murphy Professor of Neuroscience, New York University School of Medicine, Dept. of Physiology & Neuroscience

"Byrne and Roberts have put together an authoritative and beautifully produced survey of modern cellular and molecular neuroscience. The writing is clear, and the various chapters are authored by leaders in the field. A must for every neuroscientist's bookshelf."
--Charles F. Stevens, Professor and Howard Hughes Medical Institute Investigator at the Salk Institute

"...this is an excellent book that has succeeded in its primary mission: to convey our understanding of the basic information regarding cellular and molecular biology of the nerve cell, offering an excellent compilation of high-standard reviews. For graduate and advanced undergraduate students, as well as for neuroscience teachers, this is a worthwhile read. Actually, it should be considered as a primary text for a variety of courses."
--Rafael Lujan in JOURNAL OF CHEMICAL NEUROANATOMY (February 2005)

"...a superbly organized and presented college-level instructional text presupposing a heavy mathematical and scientific background as it meticulously instructs the reader concerning cellular components of nervous tissue, brain energy metabolism, molecular properties of ion channels, and more...a most welcome addition to neuroscience reference shelves."

Ratings and Reviews