Part I. Chemical and Biochemical Aspects. Chapter 1. Chemistry of iron and copper in radical reactions (W.H. Koppenol). 2. Some chemical and biochemical constraints of oxidative stress in living cells (J. Chaudière). 3. Ferryl iron and protein free radicals (C.E. Cooper). 4. Antioxidants and free radical scavengers (A.T. Diplock). 5. Formation of free radicals and mechanisms of action in normal biochemical processes and pathological states (C.A. Rice-Evans). 6. Free radicals and cell proliferation (R.H. Burdon). Part II. Pathological Aspects. 7. Therapeutic iron chelating-agents (S. Singh, R.C. Hider). 8. Free radicals in central nervous system injury (E.D. Hall). 9. Ultraviolet radiation (UVA, UVB) and skin antioxidants (L. Packer). 10. Free radicals and atherosclerosis (J.C. Fruchart, P. Duriez). 11. Chemical aspects of free radical reactions in connective tissue (B.J. Parsons). 12. Free radicals and connective tissue damage (M.S. Baker). 13. Free radicals in toxicology with an emphasis on electron spin resonance investigations (R.P. Mason, C.F. Chignell). 14. Radical generation and detection in myocardial injury (B. Kalyanaraman, E.A. Konorev, J. Joseph, J.E. Baker). 15. Free radical pathways in the inflammatory response (P.G. Winyard, C.J. Morris, V.R. Winrow, M. Zaidi, D.R. Blake). Index.