Free Energy Transduction in Biology - 1st Edition - ISBN: 9780123482501, 9780323159364

Free Energy Transduction in Biology

1st Edition

The Steady-State Kinetic and Thermodynamic Formalism

Authors: Terrell Hill
eBook ISBN: 9780323159364
Imprint: Academic Press
Published Date: 1st January 1977
Page Count: 242
Tax/VAT will be calculated at check-out Price includes VAT (GST)
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
54.95
38.47
38.47
38.47
38.47
38.47
43.96
43.96
43.99
30.79
30.79
30.79
30.79
30.79
35.19
35.19
72.95
51.06
51.06
51.06
51.06
51.06
58.36
58.36
Unavailable
Price includes VAT (GST)
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Free Energy Transduction in Biology: The Steady-State Kinetic and Thermodynamic Formalism focuses on the steady-state kinetic and thermodynamic formalism related to free energy transduction. As the word ""formalism"" implies, the discussion concerns general principles and methods and not details of proposed mechanisms in the various special cases.
Organized into seven chapters, this book first describes the diagram method, which is the main analytical tool in the study of discrete state, cycling system. The next chapter describes the essential topic of cycles and cycle fluxes. Some chapters discuss the more important bioenergetic principles that emerge from the diagram approach. This book is also concerned with somewhat more specialized aspects of the subject (stochastics and fluctuations) and interacting subsystems and multienzyme complexes, including oxidative phosphorylation.

Table of Contents


Preface

Chapter 1 The Diagram Method: States

1.1 Introduction

1.2 Diagrams for Steady-State (and Equilibrium) Systems

1.3 Directional Diagrams and the Steady-State Populations of States

1.4 Simple Examples of the Use of Directional Diagrams

1.5 Transition Fluxes and Probabilities of States

References

Chapter 2 The Diagram Method: Cycles

2.1 Cycles and Cycle Fluxes

2.2 One-Way Cycle Fluxes; Kinetics at the Cycle Level

2.3 Further Examples of Cycles and of Flux Diagrams

2.4 Calculation of State Probabilities from Cycle Fluxes

References

Chapter 3 Fluxes and Forces

3.1 Example: Membrane Transport of Two Ligands

3.2 Substrate-Product Rate Constant Relations

3.3 Example: Active Transport of Na+ and K +

3.4 Reciprocal Relations and Irreversible Thermodynamics

References

Chapter 4 Free Energy Levels of Macromolecular States

4.1 Free Energy Levels of the States

4.2 Single-Cycle Examples

4.3 Simple Multicycle Example with Two Forces

4.4 Enzyme-Substrate Modified by Ligand

References

Chapter 5 Muscle Contraction

5.1 General Principles

5.2 The Kinetic Formalism

5.3 Entropy Production and Directional Properties

5.4 Current Status of Muscle Models

5.5 Free Energy Transfer in Muscle Contraction

References

Chapter 6 Stochastics and Fluctuations at Cycle and State Levels

6.1 Stochastics of Cycle Completions

6.2 Some Further Stochastic Considerations in Muscle Contraction

6.3 State Stochastics: A Two-State System

6.4 State Stochastics: Arbitrary Diagram

References

Chapter 7 Interacting Subsystems and Multienzyme Complexes

7.1 Example: Two-Enzyme Complex

7.2 Example: Three-Enzyme Complex

7.3 Example: Two Interacting Enzymes

7.4 Oxidative Phosphorylation

References

Appendix 1 "Reduction" of a Diagram

Appendix 2 Diagram Solution for the Nix; Flux Diagrams

Appendix 3 Charged Ligand and Membrane Potential

Appendix 4 Some Properties of Single-Cycle Diagrams

Appendix 5 Light Absorbing (and Emitting) Systems

Appendix 6 Basic and Gross Free Energy Levels in a Simple Special Case

Index


Details

No. of pages:
242
Language:
English
Copyright:
© Academic Press 1977
Published:
Imprint:
Academic Press
eBook ISBN:
9780323159364

About the Author

Terrell Hill