Forensic DNA Typing

Forensic DNA Typing

Biology, Technology, and Genetics of STR Markers

2nd Edition - October 24, 2004

Write a review

  • Author: John Butler
  • eBook ISBN: 9780080470610

Purchase options

Purchase options
DRM-free (PDF)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. The book covers topics from introductory level right up to cutting edge research. High-profile cases are addressed throughout the text, near the sections dealing with the science or issues behind these cases. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. These additional chapters cover statistical genetic analysis of DNA data, an emerging field of interest to DNA research. Several chapters on statistical analysis of short tandem repeat (STR) typing data have been contributed by Dr. George Carmody, a well-respected professor in forensic genetics. Specific examples make the concepts of population genetics more understandable. This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science.

Key Features

*The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome
*Chapters cover the topic from introductory level right up to "cutting edge" research
*High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases
*NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions

Readership

Researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science. Law enforcement, legal professionals, government/legal policy makers.

Table of Contents

  • Ch. 1: Overview & History of DNA Typing
    Ch. 2: DNA Biology Review
    Ch. 3: Sample Collection, DNA Extraction, and DNA Quantitation
    Ch. 4: The Polymerase Chain Reaction (DNA Amplification)
    Ch. 5: Commonly Used Short Tandem Repeat Markers and Commercial Kits
    Ch. 6: Biology of STRs
    Ch. 7: Forensic Issues
    Ch. 8: Single Nucleotide Polymorphisms & Other Bi-allelic Markers
    Ch. 9: Y-Chromosome DNA Testing
    Ch. 10: Mitochondrial DNA Analysis
    Ch. 11: Non-Human DNA and Microbial Forensics
    Ch. 12: DNA Separation Methods
    Ch. 13: DNA Detection Methods
    Ch. 14: Instrumentation for STR Typing
    Ch. 15: STR Genotyping Issues
    Ch. 16: Laboratory Validation
    Ch. 17: New Technologies, Automation, and Expert Systems
    Ch. 18: CODIS and DNA Databases
    Ch. 19: Basic Genetic Principles, Statistics, & Probability
    Ch. 20: STR Population Database Analyses
    Ch. 21: Profile Frequency Estimates, Likelihood Ratios & Source Attribution
    Ch. 22: Approaches to Statistical Analysis of Mixtures and Degraded DNA
    Ch. 23: Kinship and Parentage Testing
    Ch. 24: Mass Disaster DNA Victim Identification

    App I: Reported STR Alleles
    App II: Population Data-STR Allele Frequencies
    App. III: Suppliers of DNA Analysis Supplies
    App. IV: DAB QA Standards
    App. V: DAB Recommendations on Statistics
    App. VI: NRC II Recommendations
    App. VII: Example DNA Cases

Product details

  • No. of pages: 688
  • Language: English
  • Copyright: © Academic Press 2005
  • Published: October 24, 2004
  • Imprint: Academic Press
  • eBook ISBN: 9780080470610

About the Author

John Butler

John M. Butler is a NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland. Dr. Butler earned his PhD from the University of Virginia while doing DNA research in the FBI Laboratory's Forensic Science Research Unit. He has won numerous scientific awards, including being named Science Watch’s #1 world-wide high-impact author in legal medicine and forensic science over the last decade (July 2011). He has over 150 publications in this field and is a frequent presenter on the topic of DNA typing, and has authored four other DNA Typing books including Advanced Topics in Forensic DNA Typing: Methodology. For a detailed CV, visit http://www.cstl.nist.gov/strbase/butler.htm.

Affiliations and Expertise

NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland.

Ratings and Reviews

Write a review

Latest reviews

(Total rating for all reviews)

  • MaximeDard Mon Dec 23 2019

    Perfect

    Perfect