fMRI in the Pre-Operative Brain Tumor Setting, An Issue of Neuroimaging Clinics of North America

1st Edition, Volume 31-1 - November 20, 2020
Editor: Andrei Holodny
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 9 6 2 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 9 6 3 - 2

This issue of Neuroimaging Clinics of North America focuses on fMRI for the Diagnosis, Treatment and Management of Brain Tumors and is edited by Dr. Andrei I. Holodny. Articles… Read more

fMRI in the Pre-Operative Brain Tumor Setting, An Issue of Neuroimaging Clinics of North America

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This issue of Neuroimaging Clinics of North America focuses on fMRI for the Diagnosis, Treatment and Management of Brain Tumors and is edited by Dr. Andrei I. Holodny. Articles will include: Introduction to fMRI; How to start your clinical fMRI program; Diffusion tractography; The problem of neurovascular uncoupling; Dynamic Resting State fMRI; Resting State fMRI of language function; Methods of fMRI analysis; Patient preparation and fMRI paradigm design; Functional brain anatomy; Neurosurgical Applications of fMRI; and more!

Cover image
Title page
Table of Contents
Copyright
CME Accreditation Page
Forthcoming Issues
Contributors
Foreword
Preface
Introduction to Functional MR Imaging
Key points
Introduction
What is functional MR imaging?
How are functional MR imaging data acquired?
How does functional MR imaging acquisition differ from anatomic MR imaging acquisition?
How are functional MR imaging data analyzed?
Challenges of functional MR imaging
The functional MR imaging workflow
Clinical usefulness of functional MR imaging
Other clinical applications and novel directions of functional MR imaging
Patient Preparation and Paradigm Design in fMRI
Key points
Introduction
Scan preparation
Patient evaluation
Language
Language paradigms
Motor
Scan set-up
Summary
Clinics care points
Methods of Analysis: Functional MRI for Presurgical Planning
Key points
Introduction
Workflow in clinical functional MRI
Image pre-processing
Statistical analysis
Summary
Functional Brain Anatomy
Key points
Introduction
Primary sensorimotor cortex
Primary motor cortex
Primary somatosensory cortex
Foot motor area
Facial motor area (tongue and lips)
Supplementary motor area
Supplementary motor area proper
Language
Language laterality index
Secondary language areas
Visual system
The Problem of Neurovascular Uncoupling
Key points
Introduction
The problem of neurovascular uncoupling in clinical functional MR imaging
Detection of brain tumor–induced neurovascular uncoupling using cerebrovascular reactivity mapping
Detection of neurovascular uncoupling in resting state functional MR imaging
Mitigation of neurovascular uncoupling using amplitude of low-frequency fluctuations
Summary
Clinics care points
Resting State Functional MR Imaging of Language Function
Key points
Introduction
Methods
Results
Discussion
Summary
Dynamic Brain Connectivity in Resting State Functional MR Imaging
Key points
Dynamic resting state functional MR imaging
Intrinsic correlations of the brain and relevance to dynamic connectivity
General methods of assessing dynamic functional connectivity
Beyond classic sliding window analyses
Summary
Clinical care points
Special articles
Utility of Preoperative Blood-Oxygen-Level–Dependent Functional MR Imaging in Patients with a Central Nervous System Neoplasm
Key points
Introduction
Blood-oxygen-level–dependent functional MR imaging and the eloquent cortex
Pitfalls of blood-oxygen-level–dependent functional MR imaging
Blood-oxygen-level–dependent functional MR imaging applications
Task-based versus resting-state blood-oxygen-level–dependent functional MR imaging
Combination functional brain imaging
Summary
Imaging Glioblastoma Posttreatment: Progression, Pseudoprogression, Pseudoresponse, Radiation Necrosis
Key points
Introduction
Conventional imaging: evolution of assessment criteria
Definition of pseudoprogression
Factors associated with pseudoprogression
Differentiating pseudoprogression from true progression
Magnetic resonance perfusion
Diffusion
Pseudoprogression in immunotherapy
Pseudoresponse
Radiation necrosis
Summary
Adult Primary Brain Neoplasm, Including 2016 World Health Organization Classification
Key points
Introduction
Imaging technique and considerations
Pathology and imaging
Summary

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Andrei Holodny