Fluorine Chemistry V4

Fluorine Chemistry V4

1st Edition - January 1, 1965

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  • Editor: J.H. Simons
  • eBook ISBN: 9780323142458

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Fluorine Chemistry, Volume IV provides an extensive survey and discussion on the physiological properties of fluoride ion and substances capable of producing it in aqueous solution. This book elaborates the detrimental effects of excessive fluoride ingestion, through the beneficial effects of optimal amounts, to recognized detrimental effects, such as dental caries accompanied by suboptimal fluoride intake. Fluoride metabolism is discussed in detail, including the capacity for storage of fluoride by the bones and rates of excretion of fluoride from the body. This text also covers the relation of fluoride ion to the health of teeth and bones. This publication is a good source for chemists and clinicians intending to acquire knowledge of the biological effects of fluoride.

Table of Contents

  • Preface



    List of Tables

    Chapter 1. Biological Properties of Inorganic Fluorides

    Acute Effects of Inorganic Fluorides

    Fatal Human Poisonings

    Nonfatal Human Poisonings

    Acute Effects of Inorganic Fluorides on Experimental Animals

    Chronic Effects of Inorganic Fluorides

    Industrial Fluorosis

    Nonindustrial Chronic Fluorosis

    Chronic Poisoning in Animals

    Metabolism of Inorganic Fluoride

    Fluoride Absorption

    Skeletal Deposition

    Effects of Fluorides on Enzyme Systems

    Effects of Inorganic Fluorides on Microorganisms

    Inorganic Fluoride Compounds Useful as Insecticides

    Supplementary Reference Material

    Chapter 2. Effects of Fluorides on Bones and Teeth

    Crippling Fluorosis

    Physical Findings

    Histological Findings

    Endemic Skeletal Fluorosis

    Industrial Fluorosis


    Fluoride Deposition in Bone


    Differential Diagnosis

    Factors Influencing Fluorosis



    Physical Properties

    Chemical Properties


    Cellular Mechanisms


    Physiological Status of Osteosclerosis


    Fluoride Content of Bone in Bone Disease

    Histogenesis and Mechanisms in the Development of Osteofluorosis




    Mottled Enamel



    Severity of Mottling vs. Fluoride Concentration in the Drinking Water



    Statistical Nature of Mottling

    Vitamin C and Fluorosis

    Climatic Conditions and Mottling

    Dental Caries


    Effect of Climate on Optimal Water Fluoridation Concentrations


    Other Routes of Administration

    Antibacterial Effects


    Time at Which Fluoride Must be Available to the Tooth in Order to Inhibit Dental Caries

    Preeruptive Fluoride Exposure

    Neo-posteruptive Exposure

    Continued Exposure

    Lack of Mottling in Deciduous Teeth

    Is the Surface Fluoride Deposited Preeruptively or After Eruption?

    Fluoridation of Water

    Hard Tissue Metabolism of Fluoride

    Bone Fluoride; Low Fluoride Diets

    Rapidity of Skeletal Deposition

    Chemical Changes Induced by Fluoride

    Physical Properties


    Supplementary Reference Material


    Subject Index

Product details

  • No. of pages: 804
  • Language: English
  • Copyright: © Academic Press 1965
  • Published: January 1, 1965
  • Imprint: Academic Press
  • eBook ISBN: 9780323142458

About the Editor

J.H. Simons

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