Fish Physiology: Homeostasis and Toxicology of Non-Essential Metals, Volume 31B

1st Edition

Print ISBN: 9781493301195
eBook ISBN: 9780123786357
Imprint: Academic Press
Published Date: 1st August 2011
Page Count: 528
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Homeostasis and Toxicology of Non-Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Ag, Al, Cd, Pb, Hg, As, Sr, and U have no known nutritive function in fish at present, but are toxic at fairly low levels.

The companion volume, Homeostasis and Toxicology of Essential Metals, Volume 31A, covers metals that are either proven to be or are strongly suspected to be essential in trace amounts, yet are toxic in higher doses. Metals such as Cu, Zn, Fe, Ni, Co, Se, Mo and Cr. In addition, three chapters in Volumes 31A and 31B on Basic Principles (Chapter 1, 31A), Field Studies and Ecological Integration (Chapter 9, 31A) and Modeling the Physiology and Toxicology of Metals (Chapter 9, 31B) act as integrative summaries and make these two volumes a vital set for readers.

Key Features

  • All major essential metals of interest are covered in metal-specific chapters
  • Each metal-specific chapter is written by fish physiologists/toxicologists who are recognized authorities for that metal
  • A common format is featured throughout this two volume edition


Fish physiologists, nutritional physiologists, toxicologists and environmental regulators

Table of Contents



1. Introduction

2. Sources of Silver and Occurrence in Natural Waters

3. Speciation in Freshwater

4. Speciation in Seawater

5. Environmental Situations of Concern

6. Acute and Chronic Ambient Water Quality Criteria in Freshwater and Seawater

7. Waterborne Silver Toxicity in Freshwater

8. Waterborne Silver Toxicity in Saltwater

9. Essentiality or Non-Essentiality of Silver

10. Potential for Bioconcentration and/or Biomagnification of Silver

11. Characterization of Uptake Routes

12. Characterization of Internal Handling

13. Characterization of Excretion Routes

14. Behavioral Effects of Silver

15. Molecular Characterization of Silver Transporters, Storage Proteins, and Chaperones

16. Genomic and Proteomic Studies

17. Interactions with Other Metals

18. Knowledge Gaps and Future Directions



1. Introduction

2. Chemical Speciation in Freshwater and Seawater

3. Sources (Natural and Anthropogenic) of Aluminum and Economic Importance

4. Environmental Situations of Concern

5. Ambient Water Quality Criteria in Freshwater

6. Mechanisms of Toxicity

7. Non-Essentiality of Aluminum

8. Potential for Bioconcentration and/or Biomagnification of Aluminum

9. Characterization of Uptake Routes

10. Characterization of Internal Handling

11. Characterization of Excretion Routes

12. Behavioral Effects of Aluminum

13. Molecular Characterization of Aluminum Transporters, Storage Proteins, and Chaperones

14. Genomic and Proteomic Studies

15. Interactions with Other Metals

16. Knowledge Gaps and Future Directions


1. Introduction

2. Chemical Speciation in Freshwater and Seawater



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"This ‘‘book’’ (actually 2 companion volumes) provides a comprehensive and accessible review of trace metal essentiality, effects of deficiency or excess, homeostatic processes, and toxicology in fishes. The chapters and volumes are constructed with a parallel structure that helps comparisons across the different metals. In addition to the core focus, each chapter includes a brief summary of geochemical speciation, environmental concentrations in natural and polluted areas, environmental quality criteria from different countries, uses, and arguments for and against essentiality. The chapters are all authoritative…These 2 volumes are likely to stand for some time as the defining compendium on the homeostasis and toxicology of metals in fish. The publisher lists them as the First Edition. Perhaps when the Second Edition is written, it will be feasible to expand the scope to include comparative information on aquatic organisms other than fish."--Integrated Environmental Assessment and Management, Volume 8, Number 4, pp. 768-772