Fish Physiology: Homeostasis and Toxicology of Essential Metals, Volume 31A

1st Edition

Series Volume Editors: Chris Wood Anthony Farrell Colin Brauner
Print ISBN: 9780123786364
eBook ISBN: 9780123786371
Imprint: Academic Press
Published Date: 28th July 2011
Page Count: 520
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Homeostasis and Toxicology of Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Cu, Zn, Fe, Ni, Co, Se, Mo and Cr are either proven to be or are strongly suspected to be essential in trace amounts, yet are toxic in higher doses.

The companion volume, Homeostasis and Toxicology of Non-Essential Metals, Volume 31B, covers metals that have no known nutritive function in fish at present, but which are toxic at fairly low levels, such as Ag, Al, Cd, Pb, Hg, As, Sr, and U. In addition, three chapters in Volumes 31A and 31B on Basic Principles (Chapter 1, 31A), Field Studies and Ecological Integration (Chapter 9, 31A) and Modeling the Physiology and Toxicology of Metals (Chapter 9, 31B) act as integrative summaries and make these two volumes a vital set for readers.

Key Features

  • All major essential metals of interest are covered in metal-specific chapters
  • Each metal-specific chapter is written by fish physiologists/toxicologists who are recognized authorities for that metal
  • A common format is featured throughout this two volume edition


Fish physiologists, nutritional physiologists, toxicologists and environmental regulators

Table of Contents

Contents of homeostasis and toxicology of non-essential metals, volume 31B



1 An introduction to metals in fish physiology and toxicology: basic principles

1 Background

2 Structure of the book

3 Chemical speciation in freshwater and seawater

4 Sources of metals and economic importance

5 Environmental situations of concern

6 Acute and chronic ambient water quality criteria

7 Mechanisms of toxicity

8 Essentiality or non-essentiality of metals

9 Potential for bioconcentration and/or biomagnification of metals

10 Characterization of uptake routes

11 Characterization of internal handling

12 Characterization of excretion routes

13 Behavioral effects of metals

14 Molecular characterization of metal transporters, storage proteins, and chaperones

15 Genomic and proteomic studies

16 Interactions with other metals

2 Copper

1 Introduction

2 Chemical speciation and other factors affecting toxicity in freshwater and seawater

3 Sources of copper in the environment and its economic importance

4 Environmental situations of concern

5 Acute and chronic ambient water quality criteria

6 Mechanisms of toxicity

7 Essentiality of copper

8 Potential for bioconcentration and biomagnification of copper

9 Characterization of uptake routes

10 Characterization of internal handling

11 Characterization of excretion routes

12 Behavioral effects of copper

13 Molecular characterization of copper transporters, storage proteins, and chaperones

14 Genomic and proteomic studies

15 Interactions with other metals

16 Knowledge gaps and future directions

3 Zinc

1 Introduction

2 Chemical speciation of zinc in freshwater and seawater

3 Sources of zinc and economic importanc


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About the Series Volume Editor

Chris Wood

Affiliations and Expertise

Dept of Biology, McMaster University, Ontario, Canada

Anthony Farrell

Tony Farrell is a graduate of Bath University, where he was fortunate to study with Peter Lutz. His fortunes grew further when he moved in 1974 to Canada and the Zoology Department at the University of British Columbia to complete his Ph.D. degree under the superb tutelage of Dave Randall. In 2004, Tony returned to UBC when he accepted an endowed research chair in Sustainable Aquaculture. In between these positions at UBC, Tony was employed at the University of Southern California (PDF), the University of New Brunswick (sessional lecturer), Mount Allison University (first real job) and Simon Fraser University (moving through the ranks to a full professor). In addition to highly controlled laboratory experiments on fish cardiorespiratory physiology, Tony is committed to working on animals in their own environment. Therefore, his research on fish physiology has taken him on an Alpha Helix expedition to the Amazon, the University of Gothenburg and the Kristineberg Marine Research Station in Sweden, the Portobello Marine Biological Station in New Zealand, the University of Christchurch and Massey University in New Zealand, the Bamfield Marine Science Station and the Huntsman Marine Station in Canada, the University of Aarhus in Denmark, the University of Adelaide Charles and Darwin University in Australia, and to the Danish Arctic Marine Station on Disco Island in Greenland. These travels have allowed him to work and with many superb collaborators word-wide, as well as study the physiology of over 70 different species of fish. Tony has received a number of awards for his scientific contributions: an honorary degree from the University of Gothenburg in Sweden; Awards of Excellence from the American Fisheries Society for Fish Physiology, Conservation and Management; the Fry Medal from the Canadian Society of Zoologists; and the Beverton Medal from the Fisheries Society of the British Isles.

Affiliations and Expertise

Dept of Zoology, University of British Columbia, Vancouver, Canada

Colin Brauner

Affiliations and Expertise

Dept of Zoology, University of British Columbia, Vancouver, Canada


"This ‘‘book’’ (actually 2 companion volumes) provides a comprehensive and accessible review of trace metal essentiality, effects of deficiency or excess, homeostatic processes, and toxicology in fishes. The chapters and volumes are constructed with a parallel structure that helps comparisons across the different metals. In addition to the core focus, each chapter includes a brief summary of geochemical speciation, environmental concentrations in natural and polluted areas, environmental quality criteria from different countries, uses, and arguments for and against essentiality. The chapters are all authoritative…These 2 volumes are likely to stand for some time as the defining compendium on the homeostasis and toxicology of metals in fish. The publisher lists them as the First Edition. Perhaps when the Second Edition is written, it will be feasible to expand the scope to include comparative information on aquatic organisms other than fish."--Integrated Environmental Assessment and Management, Volume 8, Number 4, pp. 768-772