Part 1 Introduction: Introduction to fire toxicity; Fire scenarios and combustion conditions. Part 2 Harmful effects of fire effluents: Hazards from smoke and irritants; Asphyxiant components of fire effluents; Effects of fire effluents on fire victims. Part 3 Biological assessment of fire toxicity: Experimental methods in combustion toxicology; Animal exposure studies; Application of human animal exposure studies to human fire safety; In vitro biological toxicity assessments for fire combustion products; A combined fire smoke and lung model test equipment. Part 4 Toxicity assessment using chemical analysis: Sampling and measurement of toxic fire effluents; Bench-scale generation of fire effluents; Large scale generation and characterisation of fire effluents; Effects of the material and fire conditions on toxic product yields; Estimation of toxicity during burning of common materials. Part 5 National and international fire safety regulations: Prescriptive regulations and tests considering the toxicity of fire effluents; An international standardised framework for prediction of fire gas toxicity. Part 6 Numerical simulation of fires and their hazards: Computer simulation of fire hazards and evacuation; Toxic hazard calculation models for use with fire effluent data; Modelling fire growth and toxic gas formation.