Fibroblast Growth Factors - 1st Edition - ISBN: 9780128161425

Fibroblast Growth Factors

1st Edition

Authors: Xiaokun Li
Paperback ISBN: 9780128161425
Imprint: Academic Press
Published Date: 1st June 2018
Page Count: 500
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Description

Fibroblast Growth Factors (FGFs) are a family of growth factors. They are involved in wound healing, angiogenesis, embryonic development, and endocrine signalling pathways. Fibroblast Growth Factors presents research and results from the leading research group on FGF globally, providing up to date and comprehensive coverage of this field. The book describes the history, basic research and growth engineering technology involved with FGFs, and introduces detailed research methods. The book comprises eight chapters. It details successes and problems in relation to wound healing of engineered growth factors, and consider injury repair and regeneration, non-mitogenic mutants, structure modification, pathology, physiology, pharmacology, development, FGF/FGFR inhibitors, bioengineering, and new drug development. This is a key book for researchers working on FGFs.

Key Features

  • Focusses on growth engineering aspects of FGF-based drug development and clinical application
  • Presents useful information on the history of FGFs, and basic research and growth engineering technology
  • Providesdetailed and practical research methods and results obtained on FGFs
  • Considers successes as well as problems in engineering technology involved with FGFs
  • Offers up to date and comprehensive coverage from the world’s leading research group

Readership

Scientists engaged in FGF basic research, bioengineering and biopharmaceuticals; Students of biopharmaceutics and pharmacology

Table of Contents

  1. Engineered growth factor review
    2. FGFs in injury repair and regeneration
    3. FGF non-mitogenic mutants
    4. Pathophysiology and Pharmacology of FGFs
    5. FGFs in embryonic development and reproductive functions
    6. Design and discovery of FGF/FGFR inhibitors
    7. Protein structure and modification of FGFs
    8. Bioengineering of FGFs and new drug developments

Details

No. of pages:
500
Copyright:
© Academic Press 2018
Published:
Imprint:
Academic Press
Paperback ISBN:
9780128161425

About the Author

Xiaokun Li

Xiaokun Li is Professor at Wenzhou Medical University, and has been vice director and associate professor at the Bioengineering Institute at Jinan University, China. He was among the first to study FGFs in China, and leads the largest dedicated research group in the world on the subject. In the past 20 years he has had new drugs and products approved by China SFDA. He has published 183 papers in leading international journals, and is the chair of the International Chinese FGF Association. He holds a PhD from Sun-Yat sen Medical University, and a degree in medical science from Norman Bethune Medical University in China.

Affiliations and Expertise

Professor, Wenzhou Medical University and formerly Vice Director and Associate Professor, Bioengineering Institute, Jinan University, China

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