Fetal-Placental Disorders

Fetal-Placental Disorders

1st Edition - January 1, 1972

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  • Editor: Nicholas S. Assali
  • eBook ISBN: 9781483262697

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Pathophysiology of Gestation, Volume II: Fetal-Placental Disorders covers important areas of reproduction such as maternal-fetal interrelationship, biochemistry and physiology of the fetoplacental unit, and use of amniotic fluid constituents as diagnostic tools for fetal well-being. This book is divided into five chapters. Chapter 1 deals with the disorders of placental transfer, clearly illustrating the physical and biochemical processes involved in placental exchanges between mother and fetus. The second chapter is devoted to disorders of placental endocrine functions. The various methods used for studying placental hormone production and the errors in analysis and interpretation of the results are also elaborated. The pathophysiology of amniotic fluid disorders is discussed in Chapter 3, while the genetic factors affecting growth and development from the gamete stage through fertilization and organ formation are described in Chapter 4. The last chapter considers the teratologic impact of the environmental factors on fetal growth and development. This volume is valuable to medical students and individuals concerned with the disorders of the maternal-fetal interrelationship.

Table of Contents

  • List of Contributors


    Contents of Other Volumes

    1 Disorders of Placental Transfer

    I. Introduction

    II. Physiological Transfer Mechanisms

    III. Normal Transfer of Specific Substances

    IV. Relation between Normal Placental Structure and Function

    V. Alteration in Placental Transfer Mechanisms

    VI. The Placenta and the Small-for-Gestational-Age Infant

    VII. Diagnostic Tests of Altered Placental Transfer

    VIII. Sequel of Altered Placental Function

    IX. Possible Therapy for Altered Placental Transfer

    X. Summary


    2 Disorders of Placental Endocrine Functions

    I. Introduction

    II. Methodology

    III. Altered Placental Estrogen Production

    IV. Altered Placental Progesterone Production

    V. Altered Placental Production of Polypeptide Hormones

    VI. Endocrinology of Placental Lesions


    3 Disorders of Amniotic Fluid

    I. Introduction

    II. Volume

    III. Composition

    IV. The Dynamics of Amniotic Fluid Constituents

    V. The Routes of Exchange of Amniotic Fluid Constituents

    VI. The Regulation and Aberrations of Amniotic Fluid Volume

    VII. Variations and Aberrations of Amniotic Fluid Constituents - Relation to Fetal Maturity



    4 Genetic Disorders Affecting Growth and Development

    I. Introduction

    II. Genetics of Gametes

    III. Anomalies of FertiHzation

    IV. Chromosomes in Man

    V. Molecular and Biochemical Considerations

    VI. Mendelian Factors—Chromosomal Inheritance

    VII. Polygenic Inheritance

    VIII. Extrachromosomal Inheritance

    IX. Genetics of Sex Development

    X. Genetic Factors in "Environmental" Teratology

    XI. Prenatal Diagnosis

    XII. Experimental Approaches in Mammals

    XIII. Modification of Genetic Aspects of Development (Principles of Treatment)

    XIV. Genetic Counseling

    XV. Future Prospects


    5 Environmental Effects on Development—Teratology

    I. Introduction

    II. Scope of Teratology Today

    III. The Degree of Teratogenic Risk for Man

    IV. Causes of Developmental Defects in Man

    V. Concluding Comment


    Author Index

    Subject Index

Product details

  • No. of pages: 374
  • Language: English
  • Copyright: © Academic Press 1972
  • Published: January 1, 1972
  • Imprint: Academic Press
  • eBook ISBN: 9781483262697

About the Editor

Nicholas S. Assali

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