Fetal and Neonatal Physiology - 4th Edition - ISBN: 9781416034797, 9781437736366

Fetal and Neonatal Physiology

4th Edition

Expert Consult - Online and Print, 2-Volume Set

Authors: Richard Polin Steven Abman
Hardcover ISBN: 9781416034797
eBook ISBN: 9781437736366
Imprint: Saunders
Published Date: 26th September 2011
Page Count: 2208


Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You’ll also have easy access to the complete contents and illustrations online at expertconsult.com.

Key Features

  • Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field.
  • Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation.

Table of Contents

I. Genetics: Genetics

II. Embryology: Embryology Regulation of Embryogenesis Pathophysiology of Congenital Malformations

III. The Placenta: Placental Development Regulation of the Placental Circulation Mechanisms of Transfer Across the Human Placenta Endocrine and Paracrine Function of the Human Placenta Placental Proteins Placental Separation at Birth Multiple Pregnancy

IV. Developmental Pharmacology and Pharmacokinetics: Basic Pharmacologic Principles Basic Pharmacokinetic Principles Physiochemical and Structural Properties Regulating Placental Drug Transfer Genetic Regulation of Drug Metabolism Drug Distribution During Fetal Life Drug Protein Binding During Development Development of Renal Excretion of Drugs During Ontogeny Pharmacodynamics and Receptor Sensitivity During Development Drug Abuse During Fetal and Neonatal Life Sympathoadrenal Mechanisms During Development Developmental Neuropharmacology Physiologic Differences of Clinical Significance Therapeutic Drug Monitoring in the Newborn Drug Excretion during Lactation

V.Intrauterine Growth: Intrauterine Growth and Nutrition

VI. Postnatal Growth and Nutrition: Infant Growth in the First Year of Life Endocrine and Other Factors Affecting Growth Water Requirements Energy Requirements Protein Requirements Carbohydrate Requirements Fat Metabolism and Requirements Mineral and Trace Element Requirements Vitamin Requirements Human Milk Composition and Function in the Infant Types and Methods of Feeding for Infants Nutritional Assessment Growth Outcome of Critically Ill Neonates

VII. Perinatal Iron, Trace Minerals, and Vitamin Metabolism: Iron Metabolism during Fetal and Neonatal Life Trace Element Metabolism in the Fetus and Neonate Metabolism of Vitamin A and Water Soluble Vitamins During


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© Saunders 2011
eBook ISBN:
Hardcover ISBN:

About the Author

Richard Polin

Affiliations and Expertise

William T. Speck Professor of Pediatrics, College of Physicians and Surgeons, Columbia University; Director, Division of Neonatology, Morgan Stanley Children’s Hospital of New York – Presbyterian, Columbia University Medical Center, New York, New York

Steven Abman

Affiliations and Expertise

Professor of Pediatrics, University of Colorado School of Medicine; Director, Pediatric Heart Lung Center, Children’s Hospital Colorado, Denver, Colorado


"Improved understanding of the human genome and the regulation of embryogensis has contributed in a major way to the content and new references. The editors have elimated clinical information which is easily found in neonatology text books and have achieved their goal of producing an excellent and comprehensive reference text. There is a Kindle version avaialbe and purchase of the two hard-back volumes includes access to the full text on-line. This feature is easy to use and provides a number of advantages...As a tool for identifying knowledge gaps it is a treasure trove for research scientists. It is a comprehensiverepository of present accumulated knowledge...I recommend unreservedly the purchase of this fourth edition to all European Neurology, Obstetric and Paediatric department libraries."

European  Journal of Paediatric Neurology, November 2012 

"This is the gold standard reference for fetal and neonatal physiology and developmental biology" - Doody's review service rating - 4 stars - Jay P. Goldsmith, MD