Fermentation Products
Proceedings of the Sixth International Fermentation Symposium Held in London, Canada, July 20-25, 1980
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Advances in Biotechnology, Volume III: Fermentation Products is the third of a series of three volumes and is based on the proceedings of the Sixth International Fermentation Symposium (IFS-6) held in London, Ontario, Canada, 20-25 July 1980. This volume contains 87 papers organized into nine sections. The papers under Section I deal with developments in the field of secondary metabolism (functions of secondary metabolites in the producing organisms; roles of plasmids in the biosynthesis of secondary metabolites; and protoplast fusion in industrial microorganisms). Sections II to VII examine the fermentation of antibiotics; amino acids, vitamins, and nucleotides; microbial enzymes; products from immobilized cells and enzymes; mycotoxins; and biopolymers. The final two sections present studies on bioconversions. The volume also includes the invited keynote address of Professor Hamao Umezawa ""Problems and Trends in the Development of New Antibiotics and Other Useful Microbial Products"". This volume will be a valuable resource for students and researchers in industrial microbiology, biochemical engineering and related areas, as well as managers of biotechnology.
Table of Contents
Preface
Guest Editorial: Problems and Trends in the Development of New Antibiotics and Other Useful Microbial Products
Section I. New Aspects of Secondary Metabolites
1. Possible Functions of the Peptide Antibiotics Tyrocidine and Gramicidin during Sporulation
2. The Role of Secondary Metabolism in Penicillium brevicompactum
3. A Study of Secondary Growth of Streptomyces griseoruber
4. Role of Plasmid Genes in Aureothricin Production
5. Function of Plasmids in Producers of Macrolides
6. Unstable Pleiotropic Mutation in Streptomyoes lavendulae
7. Localization of Antimycin a and Melanin Determinants in Auxotrophs of Streptomyoes sp. M-506 and in Their Prototrophic Revertants
8. Characterization of a Plasmid from Bacillus brevis ATCC 9999
9. Genetics of Penicillin Producing Organisms
10. Penicillin Production by Recombinant Strains of Penicillium chrysogenum Obtained by Fusion of Protoplasts
11. Fusion of Protoplasts of Bacillus Species
12. Studies on the Nature of Vacuoles in Protoplasts of Claviceps purpurea
Section II. Antibiotics
13. Cell-Free Biosynthesis of Macrolides and Other "Polyketide" Antibiotics
14. Cell-Free Biosynthesis of Peptide Antibiotics
15. Enzymology of Chloramphenicol Biosynthesis
16. Biosynthesis of Streptomycins
17. Enzymatic Synthesis of the Antibiotic Gramicidin S: Kinetics of Inhibition and Enzyme Destabilization
18. Terminal Steps of Patulin Biosynthesis in Penicillium urticae
19. Synthesis of Enniatins by a Multienzyme
20. Biosynthesis of Daunorubicin Glycosides: Analysis with Blocked Mutants
21. Fermentation and Biosynthesis of Sagamicin and Related Aminoglycosides in Micromonospora Sagamiensis
22. Characterization of Mutants of Streptomyoes Griseus Deregulated or Blocked in Candicidin Biosynthesis: Molecular Mechanism of Control of Antibiotic Biosynthesis
23. Study of the Molecular Mechanism of Phosphate Control of Candicidin Biosynthesis Using Phosphate-Deregulated Mutants
24. Regulation by Aromatic Amino Acids at the p-Aminobenzoic Acid Synthetase Level in S. griseus
25. Nitrogen Regulation of Penicillin G Biosynthesis in Penicillium chrysogenum
26. Carbon Catabolite Repression of Penicillin Biosynthesis
27. Regulation of Homocitrate Synthetase by Lysine in Relation to Penicillin G Biosynthesis
28. The Use of Different 1-Phenyl-N-Alkanes for Benzylpenicillin Biosynthesis by Penicillium chrysogenum
29. Analysis of the Spectrum of Secondary Metabolites of an Industrial Macrolide-producing Strain of Streptomyces hygroscopious
30. Stimulation of Leucomycin Production by Magnesium Phosphate and its Relevance to Nitrogen Catabolite Regulation
31. Regulation of the A40104 Fermentation-Production of A40104A, a Pleuromutilin Glycoside Antibiotic
32. Nitrogen Catabolite Regulation of Streptothricin Biosynthesis by Streptomyces noursei JA 3890 B
33. A New Aminoglycoside SC4-Antibiotic: Producing Organism, Fermentation and its Biological Properties
34. Studies on the Cosynthesis and Metabolic Regulation of Rifamycin SV
Section III. Amino Acids, Vitamins and Nucleotides
35. Regulation of Primary Metabolism
36. Aromatic Amino Acid Hyperproducing Mutants of Esoheriohia coli: Biochemistry, Genetics and Fermentation Kinetics
37. Utilisation de l'activite α-aminoamidasique d'une bacterie nitrilasique pour la production d'acides α-mines Stereospecifiques
38. Advances in Studies on Breeding of Amino Acid-Producing Strains in China
39. Vitamin Fermentations: B2 and B12
40. Extracellular Metabolites from Phototrophic Bacteria as Possible Intermediates in the Biosynthesis of Vitamin B12
41. Effect of Amino Acids on the Production of Biotin and the Mechanism of the Regulation of Biotin Biosynthesis in Sporobolomyces pararoseus 2553
42. Antimetabolite Substances from Bacillus ceveus
43. Control of Fermentative Production of Sugar Nucleotides and Cytidine Derivatives by Yeasts
Section IV. Microbial Enzymes
44. Production of Thermostable Cellulases and Raw Starch-Digestible Amylases by Fungi
45. Increased Production of Cellulase of Trichoderma reesei in STR and HRR by pH Cycling and Temperature Profiling
46. Cellulase Process Improvement and its Economics
47. 1,4-ß-Glucanases and 1,4-ß-Glucosidases from Penicillium janthinellum: Production, Location, Adsorption and Regulation
48. Process for the Production of Yeast-Lytic Enzymes and the Disruption of Whole Yeast Cells
49. Optimization of Cultivation Medium Composition for Lytic Enzyme Biosynthesis
50. ß-amylase Production by a Rifampin-Resistant, Asporogenous Mutant of Bacillus cereus and its Sporogenous Revertant
51. Production of Thermostable Alpha Amylase by Bacillus Apiarius CBML 152
52. Enzymatic Synthesis of 2H or 3H-Labeled Amino Acids with L-Methionine γ-Lyase
53. Enzymatic Oxidation of Methanol to Produce Formaldehyde and Hydrogen Peroxide
54. Isolation and Purification of Enzymes by Complexing with Liquid Ion Exchangers
Section V. Products from Immobilized Cells and Enzymes
55. Synthetic Prepolymer Methods for Immobilization of Biocatalysts. Application of Gel-Entrapped Microbial Cells to Bioconversions of Lipophilic Compounds in Hydrophobic Conditions
56. Industrial Applications of Fiber-Entrapped Enzymes
57. Microbial Sensors for Fermentation Control
58. Microencapsulation of Multi-Enzyme Systems
59. Catalytic Properties of Immobilized Cells of Methane-Oxidizing and Methanogenic Bacteria
60. Production of α-Keto Acids with Alginate-Entrapped Whole Cells of the Yeast Trigonopsis variabilis
61. Basic Trials on the Conversion of Cellulosic Material to Ethanol Using Yeast Coimmobilized with Cellulolytic Enzymes
62. Inhibition of Free and Immobilized Xanthine Oxidase by 6-(p-X-phenyl)pteridin-4-ones (X=H, Me, OMe, Cl, Br)
63. Photochemical Fuel Cell Using Immobilized Chloroplast-Clostridium butyricum
Section VI. Mycotoxins
64. Secondary Metabolites as Chemical Signals between Species in an Ecological Niche
65. Taxonomic Problems of Toxinogenic Molds
66. Genetic Perspective on Polyketides, Productivity, Parasexuality, Protoplasts, and Plasmids
67. Genetic Analysis of Aflatoxin Production by Aspergillus parasiticus
68. Convenient Production, Resolution, and Isotope Labeling of Cytochalasin Congeners
Section VII. Biopolymers
69. Microbial Polysaccharides
70. Scleroglucan Biopolymer Production, Properties, and Economics
71. The Effect of Citrate and Other Organic Acids in Xanthan Production
72. Emulsan Production in Acinetobacter Rag-1
73. Interaction of Acinetobacter Rag-1 Emulsan with Hydrocarbons
74. Biosurfactant and Surface Phenomena Associated with Corynebacterium lepus
75. Formation of Surface Active Glycolipids by n-Alkane Utilizing Microorganisms
76. Kinetics of the Biotechnological Production of Poly-ß-Hydroxybutyric Acid
Section VIII. Bioconversions
77. Degradation of Deoxycholic Acid by a Pseudomonas sp.
78. Production of Chenodeoxycholic Acid by Bioconversion of Dehydrocholic Acid
79. Kinetics and Optimization of Steroid Transformation in a Mixed Culture
80. Microbial Reduction of Carbon 1 and 2 Double Bond in l-α-Santonin (Microbial Transformation. XVI)
81. Isolation of l-Menthol from a Mixture of Racemic Menthols by Rhodotorula mucilaginosa and Bacillus Strains
82. Microbiological Hydroxylation of Patchoulol
83. Microbial Oxidation of ß-Myrcene
Section IX. Other Fermentations and Bioconversions
84. Factors Regulating Product Formation in Streptococcus lactis
85. Regulation of Citric Acid Production in Aspergillus niger
86. Production of 6-Aminopenicillanic Acid from Penicillin V and G by Bovista plumbea NRRL 3824 and Escherichia coli 5K (pHM 12)
87. Assay of Thymidine Phosphorylase in Whole Cell Suspensions of Escherichia coli
Contents of Other Volumes
Volume I. Scientific and Engineering Principles
Volume II. Fuels, Chemicals, Foods and Waste Treatment
Contents of "current Developments in Yeast Research" (ISY-5)
Author Index
Subject Index
Product details
- No. of pages: 616
- Language: English
- Copyright: © Pergamon 1981
- Published: January 1, 1981
- Imprint: Pergamon
- eBook ISBN: 9781483148465