Fermentation Products

Fermentation Products

Proceedings of the Sixth International Fermentation Symposium Held in London, Canada, July 20-25, 1980

1st Edition - January 1, 1981

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  • Editors: Claude Vezina, Kartar Singh
  • eBook ISBN: 9781483148465

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Advances in Biotechnology, Volume III: Fermentation Products is the third of a series of three volumes and is based on the proceedings of the Sixth International Fermentation Symposium (IFS-6) held in London, Ontario, Canada, 20-25 July 1980. This volume contains 87 papers organized into nine sections. The papers under Section I deal with developments in the field of secondary metabolism (functions of secondary metabolites in the producing organisms; roles of plasmids in the biosynthesis of secondary metabolites; and protoplast fusion in industrial microorganisms). Sections II to VII examine the fermentation of antibiotics; amino acids, vitamins, and nucleotides; microbial enzymes; products from immobilized cells and enzymes; mycotoxins; and biopolymers. The final two sections present studies on bioconversions. The volume also includes the invited keynote address of Professor Hamao Umezawa ""Problems and Trends in the Development of New Antibiotics and Other Useful Microbial Products"". This volume will be a valuable resource for students and researchers in industrial microbiology, biochemical engineering and related areas, as well as managers of biotechnology.

Table of Contents

  • Preface

    Guest Editorial: Problems and Trends in the Development of New Antibiotics and Other Useful Microbial Products

    Section I. New Aspects of Secondary Metabolites

    1. Possible Functions of the Peptide Antibiotics Tyrocidine and Gramicidin during Sporulation

    2. The Role of Secondary Metabolism in Penicillium brevicompactum

    3. A Study of Secondary Growth of Streptomyces griseoruber

    4. Role of Plasmid Genes in Aureothricin Production

    5. Function of Plasmids in Producers of Macrolides

    6. Unstable Pleiotropic Mutation in Streptomyoes lavendulae

    7. Localization of Antimycin a and Melanin Determinants in Auxotrophs of Streptomyoes sp. M-506 and in Their Prototrophic Revertants

    8. Characterization of a Plasmid from Bacillus brevis ATCC 9999

    9. Genetics of Penicillin Producing Organisms

    10. Penicillin Production by Recombinant Strains of Penicillium chrysogenum Obtained by Fusion of Protoplasts

    11. Fusion of Protoplasts of Bacillus Species

    12. Studies on the Nature of Vacuoles in Protoplasts of Claviceps purpurea

    Section II. Antibiotics

    13. Cell-Free Biosynthesis of Macrolides and Other "Polyketide" Antibiotics

    14. Cell-Free Biosynthesis of Peptide Antibiotics

    15. Enzymology of Chloramphenicol Biosynthesis

    16. Biosynthesis of Streptomycins

    17. Enzymatic Synthesis of the Antibiotic Gramicidin S: Kinetics of Inhibition and Enzyme Destabilization

    18. Terminal Steps of Patulin Biosynthesis in Penicillium urticae

    19. Synthesis of Enniatins by a Multienzyme

    20. Biosynthesis of Daunorubicin Glycosides: Analysis with Blocked Mutants

    21. Fermentation and Biosynthesis of Sagamicin and Related Aminoglycosides in Micromonospora Sagamiensis

    22. Characterization of Mutants of Streptomyoes Griseus Deregulated or Blocked in Candicidin Biosynthesis: Molecular Mechanism of Control of Antibiotic Biosynthesis

    23. Study of the Molecular Mechanism of Phosphate Control of Candicidin Biosynthesis Using Phosphate-Deregulated Mutants

    24. Regulation by Aromatic Amino Acids at the p-Aminobenzoic Acid Synthetase Level in S. griseus

    25. Nitrogen Regulation of Penicillin G Biosynthesis in Penicillium chrysogenum

    26. Carbon Catabolite Repression of Penicillin Biosynthesis

    27. Regulation of Homocitrate Synthetase by Lysine in Relation to Penicillin G Biosynthesis

    28. The Use of Different 1-Phenyl-N-Alkanes for Benzylpenicillin Biosynthesis by Penicillium chrysogenum

    29. Analysis of the Spectrum of Secondary Metabolites of an Industrial Macrolide-producing Strain of Streptomyces hygroscopious

    30. Stimulation of Leucomycin Production by Magnesium Phosphate and its Relevance to Nitrogen Catabolite Regulation

    31. Regulation of the A40104 Fermentation-Production of A40104A, a Pleuromutilin Glycoside Antibiotic

    32. Nitrogen Catabolite Regulation of Streptothricin Biosynthesis by Streptomyces noursei JA 3890 B

    33. A New Aminoglycoside SC4-Antibiotic: Producing Organism, Fermentation and its Biological Properties

    34. Studies on the Cosynthesis and Metabolic Regulation of Rifamycin SV

    Section III. Amino Acids, Vitamins and Nucleotides

    35. Regulation of Primary Metabolism

    36. Aromatic Amino Acid Hyperproducing Mutants of Esoheriohia coli: Biochemistry, Genetics and Fermentation Kinetics

    37. Utilisation de l'activite α-aminoamidasique d'une bacterie nitrilasique pour la production d'acides α-mines Stereospecifiques

    38. Advances in Studies on Breeding of Amino Acid-Producing Strains in China

    39. Vitamin Fermentations: B2 and B12

    40. Extracellular Metabolites from Phototrophic Bacteria as Possible Intermediates in the Biosynthesis of Vitamin B12

    41. Effect of Amino Acids on the Production of Biotin and the Mechanism of the Regulation of Biotin Biosynthesis in Sporobolomyces pararoseus 2553

    42. Antimetabolite Substances from Bacillus ceveus

    43. Control of Fermentative Production of Sugar Nucleotides and Cytidine Derivatives by Yeasts

    Section IV. Microbial Enzymes

    44. Production of Thermostable Cellulases and Raw Starch-Digestible Amylases by Fungi

    45. Increased Production of Cellulase of Trichoderma reesei in STR and HRR by pH Cycling and Temperature Profiling

    46. Cellulase Process Improvement and its Economics

    47. 1,4-ß-Glucanases and 1,4-ß-Glucosidases from Penicillium janthinellum: Production, Location, Adsorption and Regulation

    48. Process for the Production of Yeast-Lytic Enzymes and the Disruption of Whole Yeast Cells

    49. Optimization of Cultivation Medium Composition for Lytic Enzyme Biosynthesis

    50. ß-amylase Production by a Rifampin-Resistant, Asporogenous Mutant of Bacillus cereus and its Sporogenous Revertant

    51. Production of Thermostable Alpha Amylase by Bacillus Apiarius CBML 152

    52. Enzymatic Synthesis of 2H or 3H-Labeled Amino Acids with L-Methionine γ-Lyase

    53. Enzymatic Oxidation of Methanol to Produce Formaldehyde and Hydrogen Peroxide

    54. Isolation and Purification of Enzymes by Complexing with Liquid Ion Exchangers

    Section V. Products from Immobilized Cells and Enzymes

    55. Synthetic Prepolymer Methods for Immobilization of Biocatalysts. Application of Gel-Entrapped Microbial Cells to Bioconversions of Lipophilic Compounds in Hydrophobic Conditions

    56. Industrial Applications of Fiber-Entrapped Enzymes

    57. Microbial Sensors for Fermentation Control

    58. Microencapsulation of Multi-Enzyme Systems

    59. Catalytic Properties of Immobilized Cells of Methane-Oxidizing and Methanogenic Bacteria

    60. Production of α-Keto Acids with Alginate-Entrapped Whole Cells of the Yeast Trigonopsis variabilis

    61. Basic Trials on the Conversion of Cellulosic Material to Ethanol Using Yeast Coimmobilized with Cellulolytic Enzymes

    62. Inhibition of Free and Immobilized Xanthine Oxidase by 6-(p-X-phenyl)pteridin-4-ones (X=H, Me, OMe, Cl, Br)

    63. Photochemical Fuel Cell Using Immobilized Chloroplast-Clostridium butyricum

    Section VI. Mycotoxins

    64. Secondary Metabolites as Chemical Signals between Species in an Ecological Niche

    65. Taxonomic Problems of Toxinogenic Molds

    66. Genetic Perspective on Polyketides, Productivity, Parasexuality, Protoplasts, and Plasmids

    67. Genetic Analysis of Aflatoxin Production by Aspergillus parasiticus

    68. Convenient Production, Resolution, and Isotope Labeling of Cytochalasin Congeners

    Section VII. Biopolymers

    69. Microbial Polysaccharides

    70. Scleroglucan Biopolymer Production, Properties, and Economics

    71. The Effect of Citrate and Other Organic Acids in Xanthan Production

    72. Emulsan Production in Acinetobacter Rag-1

    73. Interaction of Acinetobacter Rag-1 Emulsan with Hydrocarbons

    74. Biosurfactant and Surface Phenomena Associated with Corynebacterium lepus

    75. Formation of Surface Active Glycolipids by n-Alkane Utilizing Microorganisms

    76. Kinetics of the Biotechnological Production of Poly-ß-Hydroxybutyric Acid

    Section VIII. Bioconversions

    77. Degradation of Deoxycholic Acid by a Pseudomonas sp.

    78. Production of Chenodeoxycholic Acid by Bioconversion of Dehydrocholic Acid

    79. Kinetics and Optimization of Steroid Transformation in a Mixed Culture

    80. Microbial Reduction of Carbon 1 and 2 Double Bond in l-α-Santonin (Microbial Transformation. XVI)

    81. Isolation of l-Menthol from a Mixture of Racemic Menthols by Rhodotorula mucilaginosa and Bacillus Strains

    82. Microbiological Hydroxylation of Patchoulol

    83. Microbial Oxidation of ß-Myrcene

    Section IX. Other Fermentations and Bioconversions

    84. Factors Regulating Product Formation in Streptococcus lactis

    85. Regulation of Citric Acid Production in Aspergillus niger

    86. Production of 6-Aminopenicillanic Acid from Penicillin V and G by Bovista plumbea NRRL 3824 and Escherichia coli 5K (pHM 12)

    87. Assay of Thymidine Phosphorylase in Whole Cell Suspensions of Escherichia coli

    Contents of Other Volumes

    Volume I. Scientific and Engineering Principles

    Volume II. Fuels, Chemicals, Foods and Waste Treatment

    Contents of "current Developments in Yeast Research" (ISY-5)

    Author Index

    Subject Index

Product details

  • No. of pages: 616
  • Language: English
  • Copyright: © Pergamon 1981
  • Published: January 1, 1981
  • Imprint: Pergamon
  • eBook ISBN: 9781483148465

About the Editors

Claude Vezina

Kartar Singh

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