Feigin and Cherry's Textbook of Pediatric Infectious Diseases - 8th Edition - ISBN: 9780323376921, 9780323392815

Feigin and Cherry's Textbook of Pediatric Infectious Diseases

8th Edition

2-Volume Set

Authors: James Cherry Gail Demmler-Harrison Sheldon Kaplan William Steinbach Peter Hotez
Hardcover ISBN: 9780323376921
eBook ISBN: 9780323392815
Imprint: Elsevier
Published Date: 29th December 2017
Page Count: 3000

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Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry’s Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today’s more aggressive infectious and resistant strains as well as emerging and re-emerging diseases

Key Features

  • Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease.
  • Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging.

Table of Contents

Feigin and Cherry’s Textbook of Pediatric Infectious Diseases, 8th edition



Part 1 - Host-Parasite Relationships and the Pathogenesis of Infectious Diseases

1. Molecular Determinants of Microbial Pathogenesis

2. Normal and Impaired Immunologic Responses to Infection

3. The Host Response to Infections: The Omics Revolution

4. Fever: Pathogenesis and Treatment

5. The Human Microbiome

6. Epidemiology and Biostatistics of Infectious Diseases

 Part 2 - Infection of Specific Organ Systems

Section 1 - Upper Respiratory Tract Infections

7. The Common Cold

8. Infections of the Oral Cavity

9. Pharyngitis (Pharyngitis, Tonsillitis, Tonsillopharyngitis, and Nasopharyngitis)

10. Uvulitis

11. Peritonsillar, Retropharyngeal, and Parapharyngeal Abscesses

12. Cervical Lymphadenitis

13. Parotitis  

14. Rhinosinusitis  

15. Otitis Externa

 16. Otitis Media

17. Mastoiditis

18. Croup (Laryngitis, Laryngotracheitis, Spasmodic Croup, Laryngotracheobronchitis, Bacterial Tracheitis, and Laryngotracheobronchopneumonitis) and Epiglottitis (Supraglottitis)

 Section 2 - Lower Respiratory Tract Infections

19. Acute Bronchitis

20. Chronic Bronchitis

21. Bronchiolitis and Infectious Asthma

22. Pediatric Community-Acquired Pneumonia

23. Empyema and Lung Absess

24. Children’s Interstitial Lung Disease and Hypersensitivity Pneumonitis

 25. Cystic Fibrosis

Section 3 - Infections of the Heart

26. Infective Endocarditis

27. Infectious Pericarditis

28. Myocarditis

29. Acute Rheumatic Fever

30. Mediastinitis  

Section 4 - Central Nervous System Infections

31. Bacterial Meningitis Beyond the Neonatal Period

 32. Parameningeal Infections.

33. Fungal Meningitis

34. Eosinophilic Meningitis

35. Aseptic Meningitis and Viral Meningitis

 36. Encephalitis and Meningoencephalitis

37. Parainfectious and Postinfectious Disorders of the Nervous System

37a. Parainfectious and Postinfectious Demyelinating Disorders of the Central Nervous System

37b. Infection-Associated Myelitis and Myelopathies of the Spinal Cord

37c. Guillain-Barreì Syndrome

Section 5 - Genitourinary Tract Infections

38. Urethritis

39. Cystitis and Pyelonephritis

40. Renal Abscess

41. Prostatitis

42. Genital Infections

Section 6 - Gastrointestinal Tract Infections

43. Esophagitis

 44. Approach to Patients with Gastrointestinal Tract Infections and Food Poisoning

45. Clostridium Difficile Infection


46. Whipple Disease

Section 7 - Liver Diseases

47. Hepatitis  

48. Cholangitis and Cholecystitis

49. Pyogenic Liver Abscess

 50. Reye Syndrome

  Section 8 - Other Intra-Abdominal Infections

51. Appendicitis and Pelvic Abscess

52. Pancreatitis

53. Peritonitis and Intra-Abdominal Abscess

54. Retroperitoneal Infections

Section 9 - Musculoskeletal Infections

55. Osteomyelitis

56. Septic Arthritis

57. Bacterial Myositis and Pyomyositis

  Section 10 - Skin Infections

58. Cutaneous Manifestatiions of Systemic Infections

59. Roseola Infantum (Exanthem Subitum)

  60. Skin Infections

  60a. Bacterial Skin Infections

  60b. Viral and Fungal Skin Infections

  Section 11 - Ocular Infectious Diseases

61. Ocular Infections

  Section 12 - Systemic Infectious Diseases

62. Bacteremia and Septic Shock

63. Fever Without Source and Fever of Unknown Origin

64. Toxic Shock Syndrome

65. Pediatric Acute Respiratory Distress Syndrome

 Section 13 - Infections of the Fetus and Newborn

66. Approach to Infections in the Fetus and Newborn

  Section 14 - Infections of the Compromised Host

67. Primary Immunodeficiency Diseases

68. The Febrile Neutropenic Patient

69. Opportunistic Infections in Hematopoietic Stem Cell Transplantation

 70. Infections in Pediatric Heart Transplantation

71. Infections in Pediatric Lung Transplantation  

72. Opportunistic Infections in Liver and Intestinal Transplantation

 73. Opportunistic Infections in Kidney Transplantation  

74. Infections Related to Prosthetic or Artificial Devices

75. Infections Related to Craniofacial Surgical Procedures

76. Infections in Burn Patients

 Section 15 - Unclassified Infectious Diseases

77. Kawasaki Disease

78. Chronic Fatigue Syndrome

Part 3 - Infections with Specific Microorganisms

Section 16 - Bacterial Infections

79. Nomenclature for Aerobic and Anaerobic Bacteria

Subsection 1 - Gram-Positive Cocci

80. Staphylococcus aureus Infections (Coagulase-Positive Staphylococci)

81. Coagulase-Negative Staphylococcal Infections

82. Group A, Group C, and Group G Beta Hemolytic Streptococcal Infections

83. Group B Streptococcal Infections

84. Enterococcal and Viridans Streptococcal Infections

85. Pneumococcal Infections

86. Miscellaneous Gram-Positive Cocci

 Subsection 2 - Gram-Negative Cocci

87. Moraxella catarrhalis

88. Meningococcal Disease

 89. Gonococcal Infections

Subsection 3 - Gram-Positive Bacilli

90. Diphtheria

91. Anthrax

 92. Bacillus Cereus and Other Bacillus Species

93. Arcanobacterium haemolyticum

94. Erysipelothrix rhusiopathiae

95. Listeriosis

96. Tuberculosis

97. Other Mycobacteria  

98. Leprosy and Buruli Ulcer: The Major Cutaneous Mycobacterioses

99. Nocardia

100. Corynebacterium and Rhodococcus

 Subsection 4 - Gram-Negative Bacilli

101. Citrobacter

102. Enterobacter

 103. Extraintestinal Pathogenic Escherichia coli

104. Diarrhea-Causing and Dysentery-Causing Escherichia coli

105. Klebsiella

106. Morganella morganii

 107. Proteus

 108. Providencia

109. Shigella

110. Serratia

111. Salmonella

112. Plague (Yersinia pestis)

113. Other Yersinia Species.

114. Miscellaneous Enterobacteriaceae

115. Aeromonas

116. Pasteurella multocida

117. Cholera

118. Vibrio parahaemolyticus

119. Vibrio vulnificus

120. Miscellaneous Non-Enterobacteriaceae Fermentative Bacilli

121. Acinetobacter

 122. Achromobacter (Alcaligenes)

123. Eikenella corrodens

124. Elizabethkingia and Chryseobacterium Species

  125. Pseudomonas and Related Genera

  126. Stenotrophomonas (Xanthomonas) maltophilia

Subsection 5 - Gram-Negative Coccobacilli

127. Aggregatibacter species

128. Brucellosis

129. Pertussis and Other Bordetella Infections

  130. Klebsiella granulomatis

131. Campylobacter jejuni

132. Tularemia

133. Haemophilus influenzae

134. Other Haemophilus Species (Ducreyi, Haemolyticus, Influenzae Biogroup Aegyptius, Parahaemolyticus, and Parainfluenzae) and Aggregatibacter (Haemophilus) aphrophilus

135. Helicobacter pylori

136. Kingella kingae


137. Legionnaires’ Disease, Pontiac Fever, and Related Illnesses

138. Streptobacillus moniliformis (Rat-Bite Fever)

139. Bartonella Infections

Subsection 6 - Treponemataceae

140. Lyme Disease

 141. Relapsing Fever

142. Leptospirosis

143. Spirillum minus (Rat-Bite Fever)

144. Syphilis

145. Nonvenereal Treponematoses

Subsection 7 - Anaerobic Bacteria

146. Clostridial Intoxication and Infection

  147. Infant Botulism

148. Tetanus

 149. Actinomycosis

150. Bacteroides, Fusobacterium, Prevotella, and Porphyromonas

Section 17 - Viral Infections

151. Classification and Nomenclature of Viruses

Subsection 1 (DNA) - Parvoviridae

152. Human Parvovirus B19

153. Human Bocaviruses

Subsection 2 (DNA) - Polyomaviridae

154. Human Polyomaviruses

155. Human Papillomaviruses

  Subsection 3 (DNA) - Adenoviridae

156. Adenoviruses

Subsection 4 (DNA) - Hepatoviridae

157. Hepatitis B and D Viruses

Subsection 5 (DNA) - Herpesviridae

158. Herpes Simplex Viruses 1 and 2

159. Cytomegalovirus

160. Epstein-Barr Virus

161. Human Herpesviruses 6A, 6B, 7, and 8

162. Varicella-Zoster Virus

Subsection 6 (DNA) - Poxviridae

163. Smallpox (Variola Virus)

164. Monkeypox and Other Poxviruses

  165. Mimiviruses

Subsection 1 (RNA) - Picornaviridae

166. Enteroviruses, Parechoviruses, and Saffold Viruses

167. Rhinoviruses

168. Hepatitis A Virus

Subsection 2 (RNA) - Caliciviridae

169. Calicivirus (Norovirus, Sapovirus, Vesivirus, Lagovirus, Nebovirus)

  170. Hepatitis E Virus

Subsection 3 (RNA) - Reoviridae

171. Reoviruses

172. Orbiviruses, Coltiviruses, and Seadornaviruses

173. Rotavirus

  Subsection 4 (RNA) - Togaviridae

174. Rubella Virus

  175. Alphaviruses

175a. Eastern Equine Encephalitis

  175b. Western Equine Encephalitis

175c. Venezuelan Equine Encephalitis

175d. Chikungunya

175e. Ross River Virus Arthritis

  175f. Other Alphaviral Infections

Subsection 5 - Flaviviridae

176. Flaviviruses


176a. St. Louis Encephalitis

176b. West Nile Virus

176c. Yellow Fever

176d. Dengue, Dengue Hemorrhagic Fever, and Severe Dengue

  176e. Japanese Encephalitis

176f. Murray Valley Encephalitis

176g. Tick-Borne Encephalitis

176h. Zika Virus Infections

  176i. Other Flaviral Infections  

177. Hepatitis C Virus

  Subsection 6 - Orthomyxoviridae

178. Influenza Viruses

Subsection 7 - Paramyxoviridae

179. Parainfluenza Viruses

180. Measles Virus

181. Mumps Virus

182. Respiratory Syncytial Virus

183. Human Metapneumovirus

  Subsection 8 - Rhabdoviridae

184. Rabies Virus

Subsection 9 - Arenaviridae and Filoviridae

185. Lymphocytic Choriomeningitis Virus

186. Arenaviral Hemorrhagic Fevers  

187. Filoviral Hemorrhagic Fever: Marburg and Ebola Virus Fevers

Subsection 10 - Coronaviridae and Toroviridae

188. Human Coronaviruses, Including Middle East Respiratory Syndrome Coronavirus

Subsection 11 - Bunyaviridae

189. Hantaviruses.

190. La Crosse Encephalitis and Other California Serogroup Viruses

191. Other Bunyaviridae  

191a. Rift Valley Fever

191b. Crimean-Congo Hemorrhagic Fever

191c. Phlebotomus Fever (Sandfly Fever)

191d. Oropouche Fever 

191e. Toscana Virus 

Subsection 12 - Retroviridae

192. Human Retroviruses  

192a. Oncoviruses (Human T-Cell Lymphotropic Viruses) and Lentiviruses (Human Immunodeficiency Virus Type 2)

192b. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome

Subsection 13 - Prion-Related Diseases

193. Transmissible Spongiform Encephalopathies (Creutzfeldt-Jakob Disease, Gerstmann-Sträussler-Scheinker Disease, Kuru, Fatal Familial Insomnia, New Variant Creutzfeldt-Jakob Disease, Sporadic Fatal Insomnia)

Section 18 - Chlamydia

194. Chlamydia Infections

Section 19 - Rickettsial Diseases

195. Rickettsial and Ehrlichial Diseases  .

Section 20 - Mycoplasma

196. Mycoplasma and Ureaplasma Infections

Section 21 - Fungal Diseases

197. Classification of Fungi

 198. Aspergillosis

  199. Blastomycosis

200. Candidiasis

201. Coccidioidomycosis

202. Paracoccidioidomycosis

203. Cryptococcosis

204. Histoplasmosis

205. Sporotrichosis

206. Mucormycosis and Entomopthoramycosis

207. Fusariosis and Scedosporiosis

208. Miscellaneous Mycoses

Section 22 - Parasitic Diseases

209. Classification and Nomenclature of Human Parasites

Subsection 1 - Protozoa

210. Amebiasis  

211. Blastocystis hominis and Blastocystis spp. Infection

212. Entamoeba coli Infection

213. Giardiasis

214. Dientamoeba fragilis Infections

215. Trichomonas Infections

216. Balantidium coli Infection  

217. Cryptosporidiosis

218. Cyclosporiasis, Cystoisosporiasis, and Microsporidiosis

 219. Babesiosis

  220. Malaria

 221. Leishmaniasis

 222. Trypanosomiasis

223. Naegleria, Acanthamoeba, and Balamuthia Infections  

224. Toxoplasmosis


225. Pneumocystis Pneumonia

 Subsection 2 - Nematodes

226. Parasitic Nematode Infections  

Subsection 3 - Cestodes

227. Cestodes

Subsection 4 - Trematodes

228. Foodborne Trematodes

229. Schistosomiasis

Subsection 5 - Arthropods

230. Arthropods

  Section 23 - Global Health

231. Global Health

232. International Travel Issues for Children

 233. Infectious Disease Considerations in International Adoptees and Refugees

  Part 4 - Therapeutics

234. Antibiotic Resistance

235. The Pharmacokinetic-Pharmacodynamic Interface: Determinants of Anti-Infective Drug Action and Efficacy in Pediatrics

236. Antibacterial Therapeutic Agents

 237. Antimicrobial Prophylaxis

238. Outpatient Intravenous Antimicrobial Therapy for Serious Infections

239. Antiviral Agents

240. Antifungal Agents

241. Drugs for Parasitic Infections

242. Immunomodulating Agents

243. Probiotics


Part 5 - Prevention of Infectious Diseases

244. Health Care–Associated Infections

245. Active Immunizing Agents

246. Passive Immunization

Section 24 - Other Preventative Considerations

247. Public Health Aspects of Infectious Disease Control

248. Infections in Out-of-Home Child Care

249. Animal and Human Bites

250. Bioterrorism  

Part 6 - Approach to the Laboratory Diagnosis of Infectious Diseases

251. Bacterial Laboratory Diagnosis

252. Fungal Laboratory Analysis: Specimen Collection, Direct Detection, and Culture

253. Viral Laboratory Diagnosis

254. Parasitic Laboratory Diagnosis



No. of pages:
© Elsevier 2017
29th December 2017
Hardcover ISBN:
eBook ISBN:

About the Authors

James Cherry

James D. Cherry, MD, MSc is a Distinguished Research Professor at the David Geffen School of Medicine at UCLA and UCLA Mattel Children’s Hospital, Division of Infectious Diseases. Dr. Cherry established one of the first formal pediatric infectious disease fellowship programs in the world in 1963 at the University of Wisconsin. In 1973 Dr. Cherry started the first pediatric infectious training program at UCLA. During his 43 years tenure at UCLA, numerous trainees have gone on to be leaders in pediatric infectious diseases in the US and around the world. Dr. Cherry has won many awards during his career.

Affiliations and Expertise

Distinguished Professor of Pediatrics, David Geffen School of Medicine at UCLA; Attending Physician, Pediatric Infectious Diseases, Mattel Children’s Hospital UCLA, Los Angeles, CA

Gail Demmler-Harrison

Affiliations and Expertise

Professor, Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine; Attending Physician, Infectious Diseases Service, Texas Children’s Hospital, Houston, TX

Sheldon Kaplan

Affiliations and Expertise

Professor and Vice-Chairman for Clinical Affairs, Head, Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine; Chief, Infectious Disease Service, Texas Children’s Hospital, Houston, TX

William Steinbach

Affiliations and Expertise

Associate Professor of Pediatrics, Molecular Genetics and Microbiology, Department of Pediatrics, Department of Molecular Genetics and Microbiology, Attending Physician, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, North Carolina

Peter Hotez

Affiliations and Expertise

Dean, National School of Tropical Medicine, Professor, Pediatrics and Molecular & Virology and Microbiology, Head, Section of Pediatric Tropical Medicine, Baylor College of Medicine; Texas Children’s Hospital Endowed Chair of Tropical Pediatrics, Director, Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development, President, Sabin Vaccine Institute, Houston, Texas, USA