Factors Affecting Neurodevelopment

Genetics, Neurology, Behavior, and Diet

1st Edition - May 29, 2021
Editors: Colin R Martin, Victor R Preedy, Rajkumar Rajendram
Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 9 8 6 - 4
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 9 8 7 - 1

Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with proper and abnormal… Read more

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Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with proper and abnormal development. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurodevelopment. In addition, the book examines in vitro and in vivo modeling of development with stem cells and model systems.

Part I: Genetics, molecular and cellular biology

1. Hereditary motor neuropathies and overlapping conditions - Vincenzo Lupo, Paula Sancho and Carmen Espino´s

2. Early life adversity and the role of the dopamine transporter (DAT1) gene in predicting childhood symptoms of ADHD and depression - Karen E. Waldie, Stephanie D’Souza, Christine Bibby, John M.D. Thompson and Edwin A. Mitchell

3. Genome-wide association studies and neurodevelopment: autism spectrum disorders and related traits - Rita M. Cantor and Jennifer K. Lowe

4. Single-nucleotide polymorphisms and cerebral palsy - Marisel Gonza´lez-Maya and Juan Antonio Gonza´lez-Barrios

5. Epigenetic regulation of corticalneurogenesis - Janine Hoffmann and Mareike Albert

6. Functions and dynamics of axonal mitochondria in development - Gianluca Gallo

7. Linking apoptosis and caspases in fetal neural tube defects - Linlin Wang and Aiguo Ren

8. Brain oxidative stress and pathophysiological significance in Down syndrome - Keiichi Ishihara

9. Linking adhesion GPCRs to glial cell development and function - Brian Chiou and Xianhua Piao

10. Immunoglobulin cell adhesion molecules of the Ig-FNIII type and neurodevelopment - J. Peter H. Burbach

11. Brain-derived neurotrophic factor and neurogenesis - Tadahiro Numakawa and Haruki Odaka

12. SLC7A5 and neural development - Tomohisa Katada and Hiroyuki Sakura

13. Linking SOX3, SRY, and disorders of neurodevelopment - Ana Carolina Tahira, Victor Hugo Calegari de Toledo, Arthur Sant’Anna Feltrin, Andre´ Rocha Barbosa, Veroˆnica Luiza Vale Euclydes Colovati, Mariana Maschietto and Helena Brentani

14. Neuronal Src homology 2 B adaptor protein 1 and brain growth - Liangyou Rui

15. Effects of extrinsic factors and intracellular signaling and transcription factors regulating the development and cell fate of spinal cord ependymal cells - Masaaki Kitada

16. Myelination, oligodendrocyte development, and associated neurodevelopmental disorders - Esraa Mohamed, John W. Bigbee and Carmen Sato-Bigbee

Part II: Neurological and imaging features

17. Magnetic resonance imaging of the developing fetal brain structures - Elka Miller, Abhijeet Taori, Jorge Davila, Liat Ben-Sira and Dafna Ben Bashat

18. Four-dimensional ultrasonography: methods, uses, and fetal neuroscience - Mihaela Grigore, Bogdan Florin Toma, Ana-Maria Grigore and Loredana-Maria Himiniuc

19. Linking histology and neurological development of the fetal and infant brain - Ivica Kostovi
20. Development of corticospinal tract axons: from embryonic stage to adulthood - Hector Ramiro Quinta´

21. Vascular endothelial growth factor and neurodevelopment - Verena Theis and Carsten Theiss

22. Brain-wide connectivity architecture: developmental aspects - Zilu Ma and Nanyin Zhang

23. Development and pathology of the germinal matrix - Nadia McMillan, Himanshu Sharma, Louis N. Manganas and Gregory W. Kirschen

24. Development of the GABAergic network in the mouse spinal cord - Shiori Kobayashi, Chigusa Shimizu-Okabe, Jeongtae Kim, Yoshinori Kosaka, Masanobu Sunagawa, Akihito Okabe and Chitoshi Takayama

25. Postnatal development, electrophysiology, and sensory sural nerves - Angel I. Melo, Rene´ Zempoalteca, Vladimir Marti´nez-A´lvarez, Kurt L. Hoffman and Ismael Jime´nez-Estrada

26. Neuroscience of developing axonal strata in the human fetal brain - Iris Zuni c Isasegi, Zeljka Krsnik and Ivica Kostovic

27. Neuroactive steroids and neurodevelopment - Silvia Diviccaro, Roberto Cosimo Melcangi and Silvia Giatti

28. Voltage and ligand-gated ion channels appearance and function in neurodevelopment - Sara Mirsadeghi and Sahar Kiani

29. Features of white matter development in very preterm children from infancy to late childhood - Courtney Gilchrist and Deanne Kim Thompson

30. The medial pulvinar: a crucial player in the development of the primate brain - Jihane Homman-Ludiye and James A. Bourne

31. Cortical sulci in the human fetal brain and development - Kiho Im

32. Causes and consequences of structural aberrations in cerebellar development - Jeroen Dudink, Sade J. Faneyte and Freek E. Hoebeek

33. The developmental code of the cerebellothalamocortical tract - Sade J. Faneyte, Jeroen Dudink and Freek E. Hoebeek

34. Prenatal exposure to progestins: impact on neurodevelopment of the child - M.-O. Soyer-Gobillard, Laura Gaspari, Paul Yao and Charles Sultan

Part III: Physiological aspects

35. Brain lesion characteristics in relation to upper limb function in children with unilateral cerebral palsy - Lisa Mailleux, Cristina Simon-Martinez, Katrijn Klingels, Els Ortibus and Hilde Feys

36. Maternal exercise and brain development - Cristiane Matte´, Caroline Peres Klein and Pauline Maciel August

37. Pyramidal neurons: physiology, pathophysiology, and postnatal development - Byron K.Y. Bitanihirwe and Tsung-Ung Wilson Woo

38. Working memory: physiology and neurodevelopment - Carlos M. Go´mez, Francisco J. Rui´z-Marti´nez, Brenda Angulo and Elena I. Rodri´guez-Marti´nez

39. EEG development during resting state - Elena I. Rodri´guez-Marti´nez, Brenda Angulo, Francisco J. Rui´z-Marti´nez and Carlos M. Go´mez

40. Availability and metabolism of thyroid hormones in the developing brain - Soledad Ba´rez-Lo´pez, Daniela Lo´pez-Espi´ndola, Carmen Grijota-Marti´nez, Ana Montero-Pedrazuela, Eva Auso´ and Ana Guadan˜o-Ferraz

Part IV: Behavior and psychopathological aspects

41. Quality of life and psychosocial functioning in childhood stroke - Fiadhnait O’Keeffe and Clodagh Cogley

42. Neuropsychological outcomes following childhood stroke - Fiadhnait O’Keeffe and Ruth Monaghan

43. Youths with autism and working memory - Charline Urbain and Margot J. Taylor

44. Episodic memory development in normal and adverse environments:the importance of critical periods - Antoine Bouyeure and Marion Noulhiane

45. Cognitive aspects of Down syndrome - Claire Enea-Drapeau and Raphaele Tsao

46. Adolescent neurocognitive development and cannabis use - B. Tervo-Clemmens, C.W. Musket, F.J. Calabro and B. Luna

47. The role of social anxiety in autism and the broader autism phenotype: evidence from childhood through adulthood - Cheryl L. Dickter and Joshua A. Burk

48. The impact of touch on bonding and neurodevelopment - Johanna Bendas and Ilona Croy

49. Catch-up growth and neurobehavioral development of small-for-gestational-age infants - Akihito Takeuchi

Part V: Diet and nutrition

50. Caloric restriction and the developing brain - Cristiane Matte

51. The influence of maternal high-fat diet consumption on neurobehavioral development - A.J. Mitchell, Matthew Selby and Elinor L. Sullivan

52. Bone mineral density and nutritional factors in children with cerebral palsy - C. A´lvarez-Zaragoza, A.A. Garci´a-Contreras, A. Rea-Rosas and E.M. Va´squez-Garibay

53. Epigallocatechin-3-gallate: linking the neurogenesis, hippocampus,
and Down syndrome - Fiorenza Stagni, Sandra Guidi and Renata Bartesaghi

54. Folic acid to prevent spina bifida and anencephaly - Vijaya Kancherla

Colin R Martin

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.

Affiliations and expertise

Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

Victor R Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.

Affiliations and expertise

Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK Visiting Professor, University of Hull, UK

Rajkumar Rajendram

Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.

Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.

Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.

Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.

Affiliations and expertise

Consultant in Internal Medicine, King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia