Evolution's Clinical Guidebook - 1st Edition - ISBN: 9780128171264, 9780128171271

Evolution's Clinical Guidebook

1st Edition

Translating Ancient Genes into Precision Medicine

Authors: Jules J. Berman
Paperback ISBN: 9780128171264
eBook ISBN: 9780128171271
Imprint: Academic Press
Published Date: 26th April 2019
Page Count: 357
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Description

Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.

Key Features

  • Offers an innovative approach, focusing on how disease-associated pathways evolved
  • Explains how the fields of phylogeny and embryology have become closely tied to the fields of genetics and bioinformatics
  • Demonstrates how students and biomedical professionals can apply the knowledge obtained in this book to the theory and practice of precision medicine

Readership

Bioinformaticians, graduate students on bioinformatics and genetics, researchers from several biomedical areas

Table of Contents

  1. Evolution, From the Beginning
    2. Shaking Up the Genome
    3. Evolution and Embryonic Development
    4. Speciation
    5. Phylogeny: Eukaryotes to Chordates
    6. Phylogeny: Craniates to Humans
    7. Trapped by Evolution
    8. Animal Models of Human Disease: Opportunities and Limitations
    9. Medical Proof of Evolution

Details

No. of pages:
357
Language:
English
Copyright:
© Academic Press 2019
Published:
26th April 2019
Imprint:
Academic Press
Paperback ISBN:
9780128171264
eBook ISBN:
9780128171271

About the Author

Jules J. Berman

Jules J. Berman received two baccalaureate degrees from MIT; in Mathematics, and in Earth and Planetary Sciences. He holds a PhD from Temple University, and an MD, from the University of Miami. He was a graduate student researcher in the Fels Cancer Research Institute, at Temple University, and at the American Health Foundation in Valhalla, New York. His postdoctoral studies were completed at the US National Institutes of Health, and his residency was completed at the George Washington University Medical Center in Washington, DC. Dr. Berman served as Chief of Anatomic Pathology, Surgical Pathology, and Cytopathology at the Veterans Administration Medical Center in Baltimore, Maryland, where he held joint appointments at the University of Maryland Medical Center and at the Johns Hopkins Medical Institutions. In 1998, he transferred to the US National Institutes of Health, as a Medical Officer, and as the Program Director for Pathology Informatics in the Cancer Diagnosis Program at the National Cancer Institute. Dr. Berman is a past president of the Association for Pathology Informatics, and the 2011 recipient of the Association's Lifetime Achievement Award. He has first-authored more than 100 journal articles and has written 18 science books. His most recent titles, published by Elsevier, include:

-Taxonomic Guide to Infectious Diseases: Understanding the Biologic Classes of Pathogenic Organisms, 1st edition (2012)
-Principles of Big Data: Preparing, Sharing, and Analyzing Complex Information (2013)
-Rare Diseases and Orphan Drugs: Keys to Understanding and Treating the Common Diseases (2014)
-Repurposing Legacy Data: Innovative Case Studies (2015)
-Data Simplification: Taming Information with Open Source Tools (2016)
-Precision Medicine and the Reinvention of Human Disease (2018)
-Principles and Practice of Big Data: Preparing, Sharing, and Analyzing Complex Information, Second Edition (2018)
-Taxonomic Guide to Infectious Diseases: Understanding the Biologic Classes of Pathogenic Organisms, 2nd edition (2019)

Affiliations and Expertise

Author with expertise in informatics, computer programming, and cancer biology

Ratings and Reviews