Contents. List of Contributors. Preface (E.E. Bittar). I Principles of Self-Assembly and Formation of Supramolecular Biological Systems. DNA Structure and Polymorphism (D.M.J. Lilley). RNA: Structure, organization, and Dynamics (B. Ehresmann and C. Ehresmann). Proteins: Structure, Organization, and Dynamics (R.B. Honzatko). II The Origins and Cellular Basis of Life. Determination and Freedom in Early Evolution (K. Dose). A Kit to Produce an Artificial Human Chromosome (A. Lima-de-Faria). The Evolution of RNA and Protein as Catalysts (L.A. Fothergill-Gilmore). The Evolution of the Mittochondrial Genome (H. de Vries). The Evolution of Prokaryotic and Eukaryotic Cells (T. Cavalier-Smith). The Autoevolution of the Human Species (A. Lima-de-Faria). Author Index. Subject Index.