Eukaryotic Transcription Factors - 5th Edition - ISBN: 9780123739834, 9780080561035

Eukaryotic Transcription Factors

5th Edition

Authors: David Latchman
Hardcover ISBN: 9780123739834
eBook ISBN: 9780080561035
Imprint: Academic Press
Published Date: 12th September 2007
Page Count: 488
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Description

DNA sequences, transcription factors and chromatin structure; Methods for studying transcription factors; RNA polymerases and the basal transcriptional complex; Families of DNA binding transcription factors; Activation of gene expression by transcription factors; Repression of gene expression by transcription factors; Regulation of transcription factor synthesis; Regulation of transcription factor activity; Transcription factors and human disease

Key Features

Brand new coverage in this edition includes:

  • Potential of transcription factors as therapeutic targets in human disease
  • Importance of histone modifications
  • Use of genome-based sequence analysis and high-throughput methods
  • Applications of the chromatin immunoprecipitation (ChIP) assay
  • Transcriptional elongation
  • Regulation by post-translational modifications
  • Regulatory networks and bioinformatics

Readership

This book is a mandatory resource for any researcher or student in the life sciences.

Table of Contents

DNA sequences, transcription factors and chromatin structure; Methods for studying transcription factors; RNA polymerases and the basal transcriptional complex; Families of DNA binding transcription factors; Activation of gene expression by transcription factors; Repression of gene expression by transcription factors; Regulation of transcription factor synthesis; Regulation of transcription factor activity; Transcription factors and human disease

Details

No. of pages:
488
Language:
English
Copyright:
© Academic Press 2007
Published:
Imprint:
Academic Press
eBook ISBN:
9780080561035
Hardcover ISBN:
9780123739834

About the Author

David Latchman

Affiliations and Expertise

Master of Birkbeck, University of London, Professor of Genetics, Birkbeck and University College London, UK