Ether Lipids Chemistry and Biology

Ether Lipids Chemistry and Biology

1st Edition - January 1, 1972

Write a review

  • Editor: Fred Snyder
  • eBook ISBN: 9780323149754

Purchase options

Purchase options
DRM-free (PDF)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Ether Lipids: Chemistry and Biology provides the major research breakthroughs in the chemistry and biology of ether lipids. This book contains 16 chapters and begins with the history of studies of ether lipids. The subsequent chapters deal with the chemical syntheses, analytical procedures, biological effects, and metabolic pathways of these lipids. Considerable chapters are devoted to the biochemical aspects of ether lipids in diverse species, such as mammals, birds, marine organisms, mollusks, protozoal, bacteria, and plants. These chapters also illustrate the suitability and usefulness of the various tissues to elucidate the role of these lipids in living systems. This text will be of value to chemists, biologists, biomedical scientists and researchers, and graduate students.

Table of Contents


  • List of Contributors

    Preface

    Nomenclature

    Chapter I The History of Ether-Linked Lipids through 1960

    I. Plasmalogens

    II. Alkoxylipids

    References

    Appendix—Biomedical Applications

    Chapter II Ether-Linked Lipids: Chemistry and Methods of Measurement

    I. Introduction

    II. Alkyl Glyceryl Ethers (1-Alkylglycerols)

    III. Dialkyl Glyceryl Ethers

    IV. Alk-1-enyl Glyceryl Ethers

    References

    Chapter III The Chemical Syntheses of Alkoxylipids

    I. Introduction

    II. Syntheses of Long-Chain Alkyl Glycerol Ethers

    III. Syntheses of Long-Chain Ether Esters of Glycerol

    IV. Syntheses of Other Neutral Alkoxylipids

    V. Syntheses of Alkoxyphospholipids

    VI. Syntheses of Some Phospholipid Analogs

    References

    Chapter IV The Chemical Synthesis of Glycerolipids Containing S-Alkyl, Hydroxy-O-alkyl, and Methoxy-O-alkyl Groups

    I. Synthesis of Glycerolipids Containing S-Alkyl Groups

    II. Synthesis of Glycerolipids Containing Hydroxy-Substituted O-Alkyl Groups

    III. Synthesis of Glycerolipids Containing Methoxy-Substituted O-Alkyl Groups

    References

    Chapter V The Chemical Syntheses of Plasmalogens

    I. Introduction

    II. Preparation of Alk-1-enyl Ethers of Glycerol

    III. Preparation of Derivatives of Alk-1-enyl Glycerol Ethers Suitable for Phosphorylation

    IV. Synthetic Alk-1-enyl Glycerol Ethers Containing Phosphate Ester Groups

    References

    Chapter VI The Chemical Syntheses of O-Alkyldihydroxyacetone Phosphate and Related Compounds

    I. Introduction

    II. Synthesis of Dihydroxyacetone Phosphate

    III. Synthesis of Acyl Derivatives of Dihydroxyacetone and Dihydroxyacetone Phosphate

    IV. Synthesis of O-Alkyl Derivatives of Dihydroxyacetone and Dihydroxyacetone Phosphate

    References

    Chapter VII The Enzymic Pathways of Ether-Linked Lipids and Their Precursors

    I. Enzymic Synthesis of Alkyl Glycerolipids

    II. Enzymic Synthesis of Plasmalogens

    III. Enzymic Synthesis of Ether Bonds in Miscellaneous Lipids and Other Compounds

    IV. Enzymic Reactions Responsible for the Biosynthesis of Ether-Linked Precursors

    V. Enzymic Degradation of Ether Linkages in Glycerolipids

    VI. Ether-Linked Glycerolipids as Substrates for Lipases, Phospholipases, and Phosphatases

    References

    Chapter VIII Biological Effects and Biomedical Applications of Alkoxylipids

    I. Introduction

    II. Toxicity of Alkoxylipids

    III. Absorption of Alkoxylipids and Use of Alkoxylipids in "Fat" Absorption Studies

    IV. Alkoxylipids as Substrates for Acyl Hydrolases

    V. Applications of Alkoxylipids in Therapy

    VI. Possible Functions of Naturally Occurring Alkoxylipids

    VII. Conclusions

    References

    Chapter IX Content, Composition, and Metabolism of Mammalian and Avian Lipids That Contain Ether Groups

    I. Introduction

    II. Content

    III. Composition

    IV. Metabolism

    V. Summary

    References

    Chapter X Ether-Linked Lipids and Fatty Alcohol Precursors in Neoplasms

    I. Introduction

    II. Nature of the Ether-Linked Aliphatic Moieties in Neoplastic Cells

    III. Ether-Linked Lipid Content in Neoplastic Cells

    IV. Fatty Alcohols in Neoplasms

    V. Metabolism of Ether-Linked Glycerolipids in Neoplasms

    References

    Chapter XI The Ether Bond in Marine Lipids

    I. Introduction

    II. Alkyl Glycerolipids

    III. Alk-1-enyl Glycerolipids

    IV. Ether-Linked Phosphatides and Miscellaneous Structures

    V. Diol Lipids

    References

    Chapter XII Ether-Linked Lipids in Molluscs

    I. Introduction

    II. Distribution

    III. Metabolism

    References

    Chapter XIII Ether-Linked Lipids in Protozoa

    I. Introduction

    II. Distribution

    III. Metabolism

    IV. Biological Function

    V. Conclusions

    References

    Chapter XIV Bacterial Plasmalogens

    I. Distribution of Plasmalogens among Bacteria

    I I . The Aldehyde Chains of Bacterial Plasmalogens

    III. Alkyl Glycerolipids in Bacteria

    IV. Bacterial Plasmalogen Biosynthesis

    V. Summary

    References

    Chapter XV Ether-Linked Lipids in Extremely Halophilic Bacteria

    I. Introduction

    II. The Extremely Halophilic Bacteria

    III. Chemistry of the Ether-Linked Lipids of Extremely Halophilic Bacteria

    IV. Metabolic Studies

    V. Function of Diphytanyl Ether Lipids in Cells of Extremely Halophilic Bacteria

    References

    Chapter XVI The Search for Alkoxylipids in Plants

    I. Introduction

    II. Alkoxylipids in Plant Tissues

    III. Conclusions

    References

    Author Index

    Subject Index


Product details

  • No. of pages: 454
  • Language: English
  • Copyright: © Academic Press 1972
  • Published: January 1, 1972
  • Imprint: Academic Press
  • eBook ISBN: 9780323149754

About the Editor

Fred Snyder

Ratings and Reviews

Write a review

There are currently no reviews for "Ether Lipids Chemistry and Biology"