Essential Human Virology

Essential Human Virology

2nd Edition - May 28, 2022

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  • Author: Jennifer Louten
  • Paperback ISBN: 9780323905657
  • eBook ISBN: 9780323914925

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Description

Essential Human Virology, Second Edition focuses on the structure and classification of viruses, virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses and emerging and dangerous viruses. Additionally, how viruses cause disease (pathogenesis) is highlighted, along with discussions on immune response to viruses, vaccines, anti-viral drugs, gene therapy, the beneficial uses of viruses, research laboratory assays and viral diagnosis assays. Fully revised and updated with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses, the book provides students with a solid foundation in virology.

Key Features

  • Focuses on human diseases and the cellular pathology that viruses cause
  • Highlights current and cutting-edge technology and associated issues
  • Presents real case studies and current news highlights in each chapter
  • Features dynamic illustrations, chapter assessment questions, key terms, and a summary of concepts, as well as an instructor website with lecture slides, a test bank and recommended activities
  • Updated and revised, with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses

Readership

Advanced undergraduate students studying virology, biology, biotechnology, microbiology, medical technology, or molecular biology. Researchers looking to enter virology as a new field

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Preface
  • What’s New
  • About the Author
  • Instructor Companion Website for the 2nd Edition
  • Chapter 1. The world of viruses
  • 1.1 The importance of studying viruses
  • 1.2 Viruses are not alive
  • 1.3 The origin of viruses
  • 1.4 The discovery of viruses
  • 1.5 How viruses are discovered today
  • Flash Card Vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 2. Virus structure and classification
  • 2.1 Common characteristics of viruses
  • 2.2 Structure of viruses
  • 2.3 Virus classification and taxonomy
  • Flash card vocabulary
  • Chapter Review Questions
  • Further Reading
  • Summary of Key Concepts
  • Chapter 3. Features of host cells: Molecular and cellular biology review
  • 3.1 The basic organization of the cell
  • 3.2 The plasma membrane, exocytosis, and endocytosis
  • 3.3 The cell cycle
  • 3.4 The central dogma of molecular biology: DNA replication
  • 3.5 The central dogma of molecular biology: RNA transcription and processing
  • 3.6 The genetic code
  • 3.7 The central dogma of molecular biology: Protein translation
  • 3.8 Promotion of viral transcription and translation processes
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 4. Virus replication
  • 4.1 Attachment
  • 4.2 Penetration
  • 4.3 Uncoating
  • 4.4 Replication
  • 4.5 Assembly
  • 4.6 Maturation
  • 4.7 Release
  • 4.8 Virus growth curves
  • Flash card vocabulary
  • CHAPTER REVIEW QUESTIONS
  • Further Reading
  • Summary of key concepts
  • Chapter 5. Virus transmission and epidemiology
  • 5.1 Portals of virus entry
  • 5.2 Dissemination within a host
  • 5.3 Portals of virus exit
  • 5.4 Patterns of infection
  • 5.5 Epidemiology
  • 5.6 Epidemiological studies
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 6. The immune response to viruses
  • 6.1 The innate immune system
  • 6.2 The adaptive immune system
  • 6.3 Viral evasion of the immune response
  • Flash card vocabulary
  • Chapter review questions
  • Further reading
  • Summary of key concepts
  • Chapter 7. Virology research and diagnosis of viral infections
  • 7.1 Collection and transport of clinical specimens
  • 7.2 Virus culture and cell/tissue specimens
  • 7.3 Detection of viral antigens or antiviral antibodies
  • 7.4 Detection of viral nucleic acids
  • Flash card vocabulary
  • Chapter review questions
  • Further reading
  • Summary of key concepts
  • Chapter 8. Vaccines, antivirals, and the beneficial uses of viruses
  • 8.1 Vaccine development
  • 8.2 Antivirals
  • 8.3 The Beneficial uses of viruses
  • Flash card vocabulary
  • Chapter review questions
  • Further reading
  • Summary of key concepts
  • Chapter 9. Viruses and cancer
  • 9.1 Properties of cancerous cells
  • 9.2 Control of the cell cycle
  • 9.3 Important genes involved in the development of cancer
  • 9.4 Oncogenic viruses
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 10. Influenza viruses
  • 10.1 Influenza taxonomy and types
  • 10.2 Clinical course of infection
  • 10.3 Molecular virology
  • 10.4 Genetic changes in the influenza genome
  • 10.5 Historic influenza antigenic shifts
  • 10.6 Highly pathogenic avian influenza viruses
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 11. Human Immunodeficiency Virus
  • 11.1 History of HIV infection
  • 11.2 Taxonomy and origins of HIV
  • 11.3 Epidemiology of HIV/AIDS
  • 11.4 Clinical progression of HIV/AIDS
  • 11.5 Molecular virology and replication of HIV-1
  • Flash card vocabulary
  • Chapter review questions
  • Further reading
  • Summary of key concepts
  • Chapter 12. Hepatitis Viruses
  • 12.1 Clinical course of hepatitis virus infections
  • 12.2 Transmission and epidemiology of hepatitis viruses
  • 12.3 Molecular virology of the hepatitis viruses
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of Key Concepts
  • Chapter 13. Herpesviruses
  • 13.1 Herpesvirus classification
  • 13.2 Clinical conditions caused by herpesviruses
  • 13.3 Molecular virology
  • 13.4 Latency
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 14. Coronaviruses
  • 14.1 Coronavirus taxonomy
  • 14.2 Coronavirus outbreaks and their origins
  • 14.3 Epidemiology and the clinical course of coronavirus infections
  • 14.4 Replication cycle of SARS-CoV-2
  • Abbreviations
  • 14.5 Coronavirus vaccine and treatment efforts
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 15. Poliovirus
  • 15.1 The early years of poliovirus
  • 15.2 Clinical course of infection
  • 15.3 Poliovirus replication
  • 15.4 Epidemiology and worldwide eradication efforts
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 16. Poxviruses
  • 16.1 Taxonomy
  • 16.2 Clinical course of variola infection
  • 16.3 Poxvirus replication cycle
  • 16.4 Eradication of smallpox
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Chapter 17. Emerging and Reemerging Viral Diseases
  • 17.1 Factors Involved in the Emergence of Viral Infectious Diseases
  • 17.2 Notable Emerging Viral Diseases
  • Flash Card Vocabulary
  • Chapter Review Questions
  • Further Reading
  • Summary of Key Concepts
  • Chapter 18. Prokaryotic viruses and other nonliving infectious agents
  • 18.1 Prokaryotic viruses
  • 18.2 Life cycles of prokaryotic viruses
  • 18.3 Ecological impacts of viruses
  • Flash card vocabulary
  • Chapter review questions
  • Further Reading
  • Summary of key concepts
  • Appendix 1:. Abbreviations
  • Appendix 2:. Glossary
  • Index

Product details

  • No. of pages: 416
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: May 28, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323905657
  • eBook ISBN: 9780323914925

About the Author

Jennifer Louten

Jennifer Louten is currently a Professor of Biology at Kennesaw State University in Georgia, USA. She has served as a Teaching Fellow and has developed courses in virology, biotechnology, immunology, and cell culture techniques. She is the recipient of an Outstanding Teaching Award, Outstanding Early Career Faculty Award, and the Student Government Association’s Faculty of the Year Award. She received her Ph.D. from Brown University Medical School, where she investigated the cellular targets of infection and the induction of type 1 interferons following infection with lymphocytic choriomeningitis virus. Before joining academia, Dr. Louten performed research in drug discovery at Schering-Plough Biopharma (currently Merck Research Laboratories). She received her Bachelor of Science in biotechnology from the Rochester Institute of Technology.

Affiliations and Expertise

Professor of Biology; Director, Scholars in STEM Program; Director, Advanced Majors Program, Kennesaw State University, Kennesaw, GA, USA

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