Essays in Toxicology

Essays in Toxicology

Volume 6

1st Edition - January 1, 1975

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  • Editor: Wayland J. Hayes
  • eBook ISBN: 9781483216461

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Essays in Toxicology, Volume 6 approaches toxicology by very different routes; two essays with materials (plastics and tobacco alkaloids), one deals with the effects of abnormal pressure, one considers the biochemistry of the lung, and one discusses poison control centers and other mechanisms for limiting the injury done by toxic materials. The book presents essays on the topological problems and untoward effects from plastic devices used in medical applications; the metabolism of tobacco alkaloids; and poisons control center. The text also includes essays on the toxicology of hypobaric and hyperbaric environments; as well as the exploitable biochemical approaches for the evaluation of toxic lung damage. Biochemists, physical chemists, neurophysiologists, epidemiologists, and social scientists will find the book invaluable.

Table of Contents

  • List of Contributors


    Contents of Previous Volumes

    1. Toxicological Problems and Untoward Effects from Plastic Devices Used in Medical Applications

    I. Introduction

    II. Polymers, Plastics, and Elastomers

    III. Short-Term Contact with Tissue

    IV. Long-Term Contact with Tissue—Carcinogenesis t

    V. Effect of the Biological Environment on Polymeric Materials

    VI. Special Problems

    VII. Conclusions


    2. The Metabolism of Tobacco Alkaloids

    I. Introduction

    II. Nicotine Metabolism—The Current Situation

    III. Smoking and Nicotine Metabolism

    IV. Minor Tobacco Alkaloid Metabolism in Man

    V. In Vitro Metabolism of Tobacco Alkaloids

    VI. Concluding Comments


    3. Poisons Control Centers—An Essay on Information and Prevention

    I. Introduction

    II. The Extent of the Problem

    III. Poisons Centers

    IV. Medical Education

    V. Declaration of Composition

    VI. Assessment of Toxicity

    VII. Warning Labeling

    VIII. Liaison with Industry

    IX. International Liaison

    X. The Dialogue

    XI. Siting and Organization of Poisons Centers

    XII. The Future


    4. Toxicology of Hypobaric and Hyperbaric Environments

    I. Introduction

    II. Effects of Altered Hydrostatic Pressure Alone

    III. Biological Effects of Inert Gases

    IV. Superimposition of Altered Pressures and Inert Gases on Exogenous Agents

    V. Pharmacotherapy of Decompression Sickness

    VI. Summary


    5. Exploitable Biochemical Approaches for the Evaluation of Toxic Lung Damage

    I. Introduction

    II. Biochemical Composition of Lung Tissue

    III. In Vivo Biosynthesis of Macromolecules in the Lung

    IV. Work with Lung Slices

    V. Isolation of Defined Populations of Lung Cells

    VI. Subcellular Fractionation of Lung Tissue

    VII. Isolation and Properties of Cell Organelles from Lung

    VIII. Examples of Toxic Lung Damage Evaluated by Biochemical Approaches

    IX. Conclusion


    Subject Index

Product details

  • No. of pages: 208
  • Language: English
  • Copyright: © Academic Press 1975
  • Published: January 1, 1975
  • Imprint: Academic Press
  • eBook ISBN: 9781483216461

About the Editor

Wayland J. Hayes

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