Epilepsy

Epilepsy

Its Phenomena in Man

1st Edition - January 1, 1973

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  • Editor: Mary A. B. Brazier
  • eBook ISBN: 9781483216607

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Description

Epilepsy: Its Phenomena in Man is a 16-chapter text that covers the wide field of the phenomena of epilepsy in man. This book emerged from the manuscripts presented by the scientific program of an alumni reunion of the Brain Research Institute of the University of California, Los Angeles. The introductory chapters review the role of electricity in the exploration and elucidation of the epileptic seizure, as well as the role of synaptic organization of the cerebral cortex in epilepsy. The succeeding chapters deal with the neuroglial impairment hypothesis, the particular forms of experimental epilepsy in man, and their corresponding surgical treatment. These topics are followed by discussions of the problem of synchronization in the spread of epileptic discharges leading to seizures and the behavioral correlations of generalized spike-wave discharge in the electroencephalogram. Other chapters explore the common anatomy of psychomotor epilepsy and schizophrenia; time of occurrence of seizures; the clinical ictal patterns and electrographic data in partial seizure cases; and the problems of analysis and interpretation of electrocerebral signals in human epilepsy. The concluding chapters consider the developments in direct recordings from epileptogenic regions in the surgical treatment of partial epilepsies. These chapters also examine the golgi survey concerning hippocampal pathology in temporal lobe epilepsy and the structural substrates of seizure foci. This book will prove useful to neuroscientists and the workers in biomedical fields critical for the understanding of epileptogenesis.

Table of Contents


  • Contributors to this Volume

    Preface

    Historical Introduction: The Role of Electricity in the Exploration and Elucidation of the Epileptic Seizure

    Text

    References

    Synaptic Organization of the Cerebral Cortex and its Role in Epilepsy

    Neuronal Circuitry of the Cerebral Cortex

    Role of Disinhibition for Cortical Epileptic Phenomena

    Visually Evoked Potentials in Patients with Epilepsy

    Conclusion

    References

    Focal Epilepsy and the Neuroglial Impairment Hypothesis

    Text

    References

    Contribution of Experimental Epilepsy to Understanding Some Particular Forms in Man

    Clinical Cases

    New Experimental Data from the Photosensitive Papio papio

    Correlations between Clinical Data and Experimental Results Obtained from Papio papio

    References

    Depth Recordings in Man in Temporal Lobe Epilepsy

    General Methodology

    Discussion

    References

    Tactical Considerations Leading to Surgical Treatment of Limbic Epilepsy

    Decisions in Selecting Patients for Surgical Consideration

    The Criteria Adopted for Depth Electrode Implantation

    Decisions Encountered in Connection with Depth Electrode Implantation

    Additional Methods of Localization

    Summary

    References

    The Problem of Synchronization in the Spread of Epileptic Discharges Leading to Seizures in Man

    Definition of the Concept of Synchronization

    Observations on Humans

    Experimental Results on Cortical Synchronization

    Anatomical Findings Supporting Columnar Organization of the Cortex

    Propagation of Seizure Waves in the Cortex: Synchronization

    References

    Electrical Seizure Discharges within the Human Brain: The Problem of Spread

    Method

    Comments

    Summary

    References

    Behavioral Correlates of Generalized Spike-Wave Discharge in the Electroencephalogram

    Spontaneous Behavior

    Experimental Behavior

    Discussion

    Concluding Remarks

    References

    Psychomotor Epilepsy and Schizophrenia: A Common Anatomy?

    Clinical Studies

    Experimental Studies

    Pharmacological Studies

    Anatomical and Histochemical Studies

    Physiological Studies

    Summary

    References

    Circadian Cycles and Seizures

    Time of Occurrence of Seizures

    Interictal Electroencephalographic Abnormality

    Sleep Deprivation

    Photic Stimulation

    Effects of Seizures on Normal Circadian Cycles

    Conclusions

    References

    Clinical Ictal Patterns and Electrographic Data in Cases of Partial Seizures of Frontal-Central-Parietal Origin

    Patient Material, Method, and Generalities

    Results

    Discussion

    Summary

    References

    Problems of Analysis and Interpretation of Electrocerebral Signals in Human Epilepsy: A Neurosurgeon’s View

    Procedure

    Duration of the Stereoelectroencephalographic Recording

    Recording of Ictal Electrical Activity

    Recording of Interictal Abnormalities

    Conclusions

    Summary

    References

    Developments in Direct Recordings from Epileptogenic Regions in the Surgical Treatment of Partial Epilepsies

    Methods

    Results

    Discussion

    Summary

    References

    Hippocampal Pathology in Temporal Lobe Epilepsy. A Golgi Survey

    Introductory Anatomical Comments

    Pathological Changes in the Hippocampus

    Pathology of the Dentate Granules

    Neuroglia

    Conclusions

    References

    Structural Substrates of Seizure Foci in the Human Temporal Lobe

    (A Combined Electrophysiological Optical Microscopic and Ultrastructural Study)

    Materials and Methods

    Clinical Observations

    Ultrastructural Studies

    Discussion

    Summary

    References

    Author Index

    Subject Index

Product details

  • No. of pages: 404
  • Language: English
  • Copyright: © Academic Press 1973
  • Published: January 1, 1973
  • Imprint: Academic Press
  • eBook ISBN: 9781483216607

About the Editor

Mary A. B. Brazier

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