Epigenetics and Psychiatric Disease

Epigenetics and Psychiatric Disease

1st Edition - June 22, 2018

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  • Editor: Dennis Grayson
  • Hardcover ISBN: 9780128135655
  • eBook ISBN: 9780128135662

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Epigenetics and Psychiatric Disease, Volume 157, the latest volume in the Progress in Molecular Biology and Translational Science series, includes recent developments on a variety of topics, including the Epigenetic landscapes of the adversity-exposed brain, Chromosomal conformations and epigenomic regulation in schizophrenia, Progress in the epigenetics of depression, the epigenetics of circadian rhythms in imprinted neurodevelopmental disorders, DNA methylation mediating substance abuse, mechanisms and therapeutic opportunities, DNA methylation in animals model of psychosis, Epigenetics of early life stress, Epigenetic drugs for mood disorders, and more.

Key Features

  • Accessible to students and researchers alike, with content that appeals to a variety of readers
  • Written by leading authorities in their respective fields of molecular biology


Students, researchers, microbiologists, molecular biologists

Table of Contents

  • 1. Epigenetic Landscapes of the Adversity-exposed Brain
    Tania L. Roth
    2. Chromosomal Conformations and Epigenomic Regulation in Schizophrenia
    Schahram Akbarian
    3. Progress in Epigenetics of Depression
    Eric J. Nestler
    4. Epigenetics of circadian rhythms in imprinted neurodevelopmental disorders
    Janine M. LaSalle
    5. DNA methylation mediating substance abuse; mechanisms and therapeutic opportunities
    Moshe Szyf
    6. DNA Methylation in Animals Model of Psychosis
    Alessandro Guidotti and Dennis R. Grayson
    7. Epigenetics of early life stress
    Chris Murgatroyd
    8. Epigenetic Drugs for Mood Disorders
    Jacob Peedicayil
    9. Behind Epigenetic Alterations in Psychiatric Diseases
    Hamid M. Abdolmaleky
    10. DNA methylation and its possible role in psychiatric disorders
    Chunyu Liu
    11. Neuroepigenetics of suicide brain
    ogesh Dwivedi
    12. Epigenetic Mechanisms of Traumatic Brain Injuries
    Amul Sakharkar
    13. Non-protein-coding RNAs in Fetal Alcohol Spectrum Disorders
    Rajesh C. Miranda
    14. Targeting histone-modifications as a therapeutic approach to treat psychosis
    Andre Fischer
    15. The epigenetics of early life adversity: current limitations and possible solutions
    Gustavo Turecki

Product details

  • No. of pages: 450
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: June 22, 2018
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128135655
  • eBook ISBN: 9780128135662

About the Serial Volume Editor

Dennis Grayson

Dr Dennis R. Grayson received his PhD from the Department of Biochemistry at Wayne State University School of Medicine in 1984. He has been interested in mechanisms associated with gene expression for over 35 years. He joined the laboratory of Dr James E. Darnell at the Rockefeller University as a Post-Doctoral Fellow in 1984 to study cell-type specific transcription factors and their interaction with promoters and enhancers. In 1988, Dr Grayson joined the Fidia-Georgetown Institute for the Neurosciences at Georgetown University to study gene expression programs in neurons and continued this research program at Allegheny Singer Research Institute in Pittsburgh from 1995 to 1998. He continued his interests in psychiatry and joined the Psychiatric Institute at the University of Illinois in 1998. This represented a unique opportunity to pursue the molecular underpinnings of schizophrenia. Dr Grayson has received NRSA post-doctoral support, and R01 and K04 funding from the National Institutes of Health to support his work. He has published over 140 papers in peer-reviewed journals and is regularly invited to speak at numerous national and international meetings. He is currently Director of the Epigenetic Core of the Center for Alcohol Research in Epigenetics.

Affiliations and Expertise

Professor of Molecular Neuroscience, University of Illinois at Chicago, IL, USA

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