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Epigenetics and Metabolomics - 1st Edition - ISBN: 9780323856522

Epigenetics and Metabolomics, Volume 27

1st Edition

Editors: Paban Agrawala Poonam Rana
Series Editor: Trygve Tollefsbol
Paperback ISBN: 9780323856522
Imprint: Academic Press
Published Date: 1st August 2021
Page Count: 360
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Table of Contents

  1. Epigenetics in translational Medicine
    2. Metabolomics techniques: A brief Update
    3. Integration of epigenomics and metabolomics: From biomarkers discovery to personalized medicine
    4. Epigenetic Regulation of Oncogenes
    5. Epigenetics and Metabolism in Neurodegenrative diseases
    6. Genome-wide identification and transcriptional analysis of diphthamide biosynthesis pathway in malaria parasite
    7. Radiation responsive metabolic alterations: An update
    8. Epigenetic and metabolic changes in Blast induced traumatic brain injury
    9. Recent advances of epigenetics in plant sciences
    10. Plant derived HDAC inhibitor chrysin in anticancer therapy
    11. Epigenetic regulation of neuronal development and function

Description

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare.

Key Features

  • Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research
  • Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others
  • Provides guidance in epigenomics and metabolomic research methodology

Readership

Human geneticists; human genomicists; translational researchers in genomic medicine, epigenetics, biochemistry, molecular biology, oncology, neurology, and bioinformatics; life science researchers; developmental biologists. Clinicians and graduate students in the biosciences


Details

No. of pages:
360
Language:
English
Copyright:
© Academic Press 2021
Published:
1st August 2021
Imprint:
Academic Press
Paperback ISBN:
9780323856522

Ratings and Reviews


About the Editors

Paban Agrawala

Dr. Paban K. Agrawala Ph.D is a Scientist in the Radiation Epigenetics Division at the Institute of Nuclear Medicine and Allied Sciences in New Delhi, India, and previously was a Post doctoral Research Associate at Brookhaven National Lab, New York, USA. Dr. Agrawala is a member of the Indian Society for Radiation Biology, as well the Flowcytometry Society of India. He has published widely in such peer reviewed journals as the International Journal of Radiation Biology; Frontiers in Immunology; Current Topics in Medicinal Chemistry; and the Journal of Environmental Pathology, Toxicology, and Oncology. His current research focuses on understanding the epigenetic changes, especially histone acetyltion status, following exposure to ionizing radiation.

Affiliations and Expertise

Radiation Epigenetics Division, Institute of Nuclear Medicine and Allied Sciences, New Delhi, India

Poonam Rana

Dr. Poonam Rana Phd is a Senior Scientist at the Institute of Nuclear Medicine & Allied Sciences, under Ministry of Defence, Delhi, India. She received her PhD at the CCS Haryana Agricultural University in Hisar, India. Her focus of research is applications of metabolomics and imaging in identification of biomarkers for traumatic brain injury and radiation exposure during combat emergencies. She has published widely in such peer reviewed journals as the Scientific Reports, Metabolomics, Journal of Neuroendocrinology, International Journal of Radiation Biology, Journal of Neuroscience Research, and Chemical Biological Interactions.

Affiliations and Expertise

Nuclear Medicine and Allied Sciences, Ministry of Defence, Timarpur, New Delhi, India

About the Series Editor

Trygve Tollefsbol

Trygve Tollefsbol is a Professor of Biology and a Senior Scientist in the Comprehensive Center for Healthy Aging, the Comprehensive Cancer Center, the Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol has doctorate degrees in molecular biology and osteopathic medicine and has edited and co-authored numerous books on the topics of epigenetics, cancer and aging and is Series Editor of Translational Epigenetics. Dr. Tollefsbol is a Professor of Biology and a Senior Scientist in the Center for Aging, Comprehensive Cancer Center, Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999 and a Steering Committee Member of the UAB Center for Aging.

Affiliations and Expertise

Professor of Biology, Senior Scientist, Comprehensive Cancer Center, Comprehensive Center for Healthy Aging, University of Alabama at Birmingham, AL, USA