Epigenetics and Cancer, Part A, Volume 70

1. Introduction, objectives of the book

Zdenko Herceg and Toshikazu Ushijima

Section I. Basic epigenetic mechanisms in the regulation of critical cellular processes

2. DNA methylation and cancer

Manel Esteller

3. Histone modifications and cancer

Zdenko Herceg

4. Epigenetics and miRNAs in human cancer

George A Calin

5. Interplay between different epigenetic mechanisms

Rabih Murr

 

Section II. Epigenetic events underlying biological phenomena

6. Genomic imprinting and cancer

Eamonn Maher

7. Epigenetic code and stem cells

Yasuhiro Yamada

8. Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility

Megan Hitchins

Section III. Cancer epigenome

9. Cancer epigenome

Stephan Beck

10. Identification of driver methylation by epigenomic analysis

Gerd Pfeifer

11. Epigenetic driver of genetic alterations

Minoru Toyota

Section VI. Epigenetic therapy and epigenetic drugs

12. DNA demethylating agents and epigenetic therapy of cancer

Mani Samson and Zdenko Herceg

13. Histone modification therapy of cancer

Severio Minucci

Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

• Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models
• Includes methods for testing with ethical, legal, and social implications
• Critically analyzes future prospects

Geneticists, molecular biologists, neurobiologists