Description Table of Contents Details Serial Volume Editors

Description

Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

Key Features

* Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models * Includes methods for testing with ethical, legal, and social implications * Critically analyzes future prospects

Readership

Geneticists, molecular biologists, neurobiologists

Table of Contents

  1. Introduction, objectives of the book

    2. Zdenko Herceg and Toshikazu Ushijima

    Section I. Basic epigenetic mechanisms in the regulation of critical cellular processes

  2. DNA methylation and cancer

    3. Manel Esteller

  3. Histone modifications and cancer

    4. Zdenko Herceg

  4. Epigenetics and miRNAs in human cancer

    5. George A Calin

  5. Interplay between different epigenetic mechanisms

    6. Rabih Murr

     

    Section II. Epigenetic events underlying biological phenomena

  6. Genomic imprinting and cancer

    7. Eamonn Maher

  7. Epigenetic code and stem cells

    8. Yasuhiro Yamada

  8. Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility

    9. Megan Hitchins

    Section III. Cancer epigenome

  9. Cancer epigenome

    10. Stephan Beck

  10. Identification of driver methylation by epigenomic analysis

    11. Gerd Pfeifer

  11. Epigenetic driver of genetic alterations

    12. Minoru Toyota

    Section VI. Epigenetic therapy and epigenetic drugs

  12. DNA demethylating agents and epigenetic therapy of cancer

    13. Mani Samson and Zdenko Herceg

  13. Histone modification therapy of cancer

Severio Minucci

Details

No. of pages:
394
Language:
English
Copyright:
© 2010
Published:
Imprint:
Academic Press
eBook ISBN:
9780123808677
Print ISBN:
9780123808660

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