Epigenetics and Cancer, Part A
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Epigenetics and Cancer, Part A

1st Edition - October 14, 2010

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  • Editors: Zdenko Herceg, Toshikazu Ushijima
  • eBook ISBN: 9780123808677

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Description

Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

Key Features

  • Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models
  • Includes methods for testing with ethical, legal, and social implications
  • Critically analyzes future prospects

Readership

Geneticists, molecular biologists, neurobiologists

Table of Contents

    1. Introduction, objectives of the book

      2. Zdenko Herceg and Toshikazu Ushijima

      Section I. Basic epigenetic mechanisms in the regulation of critical cellular processes

    2. DNA methylation and cancer

      3. Manel Esteller

    3. Histone modifications and cancer

      4. Zdenko Herceg

    4. Epigenetics and miRNAs in human cancer

      5. George A Calin

    5. Interplay between different epigenetic mechanisms

      6. Rabih Murr

       

      Section II. Epigenetic events underlying biological phenomena

    6. Genomic imprinting and cancer

      7. Eamonn Maher

    7. Epigenetic code and stem cells

      8. Yasuhiro Yamada

    8. Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility

      9. Megan Hitchins

      Section III. Cancer epigenome

    9. Cancer epigenome

      10. Stephan Beck

    10. Identification of driver methylation by epigenomic analysis

      11. Gerd Pfeifer

    11. Epigenetic driver of genetic alterations

      12. Minoru Toyota

      Section VI. Epigenetic therapy and epigenetic drugs

    12. DNA demethylating agents and epigenetic therapy of cancer

      13. Mani Samson and Zdenko Herceg

    13. Histone modification therapy of cancer

    Severio Minucci

Product details

  • No. of pages: 394
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: October 14, 2010
  • Imprint: Academic Press
  • eBook ISBN: 9780123808677

About the Serial Volume Editors

Zdenko Herceg

Toshikazu Ushijima

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