Epigenetics and Cancer, Part A

Epigenetics and Cancer, Part A

1st Edition - October 14, 2010

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  • Editors: Zdenko Herceg, Toshikazu Ushijima
  • eBook ISBN: 9780123808677

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Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

Key Features

  • Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models
  • Includes methods for testing with ethical, legal, and social implications
  • Critically analyzes future prospects


Geneticists, molecular biologists, neurobiologists

Table of Contents

    1. Introduction, objectives of the book
    2. Zdenko Herceg and Toshikazu Ushijima

      Section I. Basic epigenetic mechanisms in the regulation of critical cellular processes

    3. DNA methylation and cancer
    4. Manel Esteller

    5. Histone modifications and cancer
    6. Zdenko Herceg

    7. Epigenetics and miRNAs in human cancer
    8. George A Calin

    9. Interplay between different epigenetic mechanisms
    10. Rabih Murr


      Section II. Epigenetic events underlying biological phenomena

    11. Genomic imprinting and cancer
    12. Eamonn Maher

    13. Epigenetic code and stem cells
    14. Yasuhiro Yamada

    15. Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility
    16. Megan Hitchins

      Section III. Cancer epigenome

    17. Cancer epigenome
    18. Stephan Beck

    19. Identification of driver methylation by epigenomic analysis
    20. Gerd Pfeifer

    21. Epigenetic driver of genetic alterations
    22. Minoru Toyota

      Section VI. Epigenetic therapy and epigenetic drugs

    23. DNA demethylating agents and epigenetic therapy of cancer
    24. Mani Samson and Zdenko Herceg

    25. Histone modification therapy of cancer

    Severio Minucci

Product details

  • No. of pages: 394
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: October 14, 2010
  • Imprint: Academic Press
  • eBook ISBN: 9780123808677

About the Serial Volume Editors

Zdenko Herceg

Toshikazu Ushijima

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