Enzyme Regulation and Mechanism of Action

Enzyme Regulation and Mechanism of Action

Proceedings of the FEBS Special Meeting on Enzymes, Cavtat, Dubrovnik, 1979

1st Edition - January 1, 1980

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  • Editors: P. Mildner, B. Ries
  • eBook ISBN: 9781483189130

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Description

Enzyme Regulation and Mechanism of Action contains the proceedings of the Federation of European Biochemical Societies' Special Meeting on Enzymes held in Dubrovnik, Croatia in 1979. The meeting provided a forum for reviewing advances in understanding the regulation and mechanism of action of enzymes. The discussions are organized around three themes: regulation of enzyme activity; the role of enzymes in the synthesis of nucleic acids and proteins; and proteolytic enzymes. Comprised of 33 chapters, this volume begins with an analysis of partial amino acid sequence of rabbit liver fructose 1,6-bisphophatase and sites of cleavage by proteinases. The reader is then introduced to physiological inactivation of enzymes in yeasts; structure and functions of protein kinases; and control points in the citric acid cycle. Subsequent chapters focus on ligand binding properties and subunit interactions in yeast alcohol dehydrogenase; the role of water in the acceleration of an enzymatic reaction; DNA polymerases of human normal and leukemic cells; and the phylogenetic and developmental aspects of gastric proteinases and their zymogens. This book is intended for enzymologists.

Table of Contents


  • Preface

    List of Contributors

    Regulation of Enzyme Activity

    Partial Amino Acid Sequence of Rabbit Liver Fructose 1,6-Bisphophatase (Fru-P2ase, EC 3.1.3.11) and Sites of Cleavage by Proteinases

    Physiological Inactivation of Enzymes in Yeasts

    Structural Requirements of a Rat Liver Proteinkinase Displaying a Specificity Similar to that of the Mammary Gland Caseinkinase(s)

    Structure and Functions of Protein Kinases

    Structure, Function and Regulation of the Mammalian Pyruvate Dehydrogenases Complex

    Role of Enzyme Catalyzed Covalent Modifications in Regulation of Glutamine Synthetase

    Control Points in the Citric Acid Cycle

    Acid Phosphatase, a Glycoprotein of the Yeast Cell Wall

    Ligand Binding Properties and Subunit Interactions in Yeast Alcohol Dehydrogenase

    Probing of Enzyme Microenvironment of Fluorescein Derivatives

    On the Role of Water in the Acceleration of an Enzymatic Reaction

    Enzymes in Nucleic Acid and Protein Synthesis

    Restriction Nucleases in the Analysis of Bovine 1.706 Satelite DNA

    Enzymatic Synthesis of Site-Specific Mutation in an Essential Gene of Bacteriophage øX174

    DNA Polymerases of Human Normal and Leukemic Cells

    Comparative Studies of Structure and Function of DNA-Dependent RNA Polymerases from Eubacteria and Archabacteria

    In Vitro Transcription of Cloned Eukaryotic tRNA Genes

    Crystallographic Studies of Tyrosol tRNA Synthetase

    Molecular Enzymology of Tryptophanyl-tRNA Synthetase from Beef Pancreas

    Aminoacyl-tRNA Synthetases: Interactions with their Ligands

    Proofreading Process in Protein Biosynthesis on the Mechanism of Aminoacylation of tRNA

    Polynucleotide Phosphorylase as a Probe for the Regulatory Function of the 3'-OH Region of mRNA and Viral RNA in Translation

    Cortisol Mediated Control at the Translation Level in Anabolic Target Liver Cells. Modulation of Translation, and Ribosomal Proteins Phosphorylation

    Coordinacy in the Induction of Acid Glycosidases by Testosterone in Mice

    Proteolytic Enzymes

    Gastric Proteinases and their Zymogens. Phylogenetic and Developmental Aspects

    The Active Site of Acid Proteinases

    Structure and Function of Cathepsin D

    Thiol Proteinases of Human Lysosomes

    Carboxyl and Thiol Intracellular Proteinases

    Intracellular Serine Proteinases of Bacteria - Isolation, Chemistry, Evolutionary Aspects

    Proteinases and Endogenous Proteinase Inhibitors in Yeast

    The Structure-Function Relationships of Collagenolytic Enzymes

    Intracellular Neutral Proteinases and their Inhibitors

    Characteristics of the Uptake and Degradation of Yeast Invertase in Rat Tissues

    Author Index

    Subject Index

Product details

  • No. of pages: 428
  • Language: English
  • Copyright: © Pergamon 1980
  • Published: January 1, 1980
  • Imprint: Pergamon
  • eBook ISBN: 9781483189130

About the Editors

P. Mildner

B. Ries

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